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Genomics · Genetic Reports · Precision Wellness

Bone Health Package

Personalized 2-Report Genetic Package
Bone HealthJoint & Tendon Health
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-31B9E0
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-31B9E0
Reports in package
2
Results scored
44
Need attention
12
Report
Full Report

The reports inside this package

This one document contains 2 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Bone Health17 results reported of 17 analytes · 50 recommendations
Joint & Tendon Health27 results reported of 27 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 44 results here, 12 came back worth discussing with a clinician and 7 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (12)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Bone Health report
ABone Cancer
More likely
Higher predisposition than average
PARM1 rs17248137 AA · LRMDA rs17465450 AA · MECOM rs6797464 GG · GPD1L rs4955138 AA · HSPB8 rs12146774 TC · ADAMTS6 rs17206779 TC · DLEU7 rs573666 CC
AHypoparathyroidism
More likely
Higher predisposition than average
ACalcium
Increased need
Higher predisposition than average
CTNNB1 rs389264 CC · RSPO3 rs9482772 CC · AMT rs34240317 IA · CPED1 rs10242100 AA · ARL4C rs12151790 GG · FKBP11 rs3741619 GA · ETS2 rs11088458 AG · HBZ rs10794639 GA
AVitamin K
Increased need
Higher predisposition than average
CDO1 rs6862071 AT · CDO1 rs4122275 GA · SIDT2 rs964184 CC · CTNNA2 rs4852146 TT · CYP4F2 rs2108622 CC · KCNK9 rs4645543 CC
From your Joint & Tendon Health report
AHeel Pain (Plantar Fasciitis)
More likely
Higher predisposition than 99% of people
NQO1 rs62051384 CC
ANeck Arthritis
More likely
Higher predisposition than 98% of people
AShoulder Impingement
More likely
Higher predisposition than 90% of people
RFC3 rs7139664 AG · C5ORF63 rs145648292 GG · S100A12 rs143640806 AA · LONRF1 rs17769850 TT · FRMPD4 rs144371252 A · KBTBD3 rs505416 GG · PLCB1 rs6140637 AA · EGFLAM rs60486174 TT
ADisc Degeneration
More likely
Higher predisposition than 90% of people
ZEB1 rs2484990 CC · ZEB1 rs1250307 AA · ZEB1 rs2484992 CC · EYS rs11754641 CC · DCT rs9301951 TT · LRRN1 rs17034687 CC · CILP rs2073711 AG · PSMB9 rs2187689 TC
ATrigger Finger
More likely
Higher predisposition than 87% of people
TNP1 rs10203066 GG · LTBP3 rs4244811 GA · CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
AJaw Disorders (TMJ)
More likely
Higher predisposition than 81% of people
BAHCC1 rs1531554 CC · RXFP2 rs60249166 TC · ANKK1 rs1800497 GA · HTR2A rs6313 GA · EPHA5 rs201194999 CC · COL11A1 rs2622873 TT · ICA1L rs62182810 AA · SFRP1 rs10092633 GG
ADupuytren’s Contracture
More likely
Higher predisposition than 80% of people
MAFB rs12481661 GG · WNT7B rs117707689 CC · RAB31 rs11665156 CC · DUXA rs11672486 TT · MAFB rs181089987 TT · KDR rs73818546 GG · SULF1 rs2162353 GG · MAFB rs58716951 CC
ASpinal Arthritis
More likely
Higher predisposition than average
SOX5 rs148034983 TT · KCNC2 rs77092580 AA · LRPAP1 rs11735173 CC · DACH1 rs7982150 AA · MUL1 rs72649149 CC · FAM120B rs875421 TT · SUMF1 rs314440 GG · XYLT1 rs59587833 AG
Running above the typical range  (2)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Bone Health report
HGC (Vitamin D)
Higher activity
Above the typical range
GC rs2282679 GT
From your Joint & Tendon Health report
HMMP1 (Collagen)
Higher activity
Above the typical range
MMP1 rs1799750 TT
Running below the typical range  (0)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Nothing in this group.
Working in your favour  (7)Good news. Your genetics look protective or better than average here.
From your Bone Health report
FScoliosis
Less likely
Lower predisposition than 81% of people
DPCD rs11190870 CT · OBSCN rs12029076 GG · CCDC171 rs78223574 AA · FTO rs12149832 GG · TBX1 rs1978060 GG · CREB5 rs160335 GG · ADGRG6 rs9389985 GA · BNC2 rs7028900 CG
FBone Spurs
Less likely
Lower predisposition than 95% of people
CAPRIN2 rs542887566 CC · NPAP1 rs577272962 AA · PIK3R1 rs143106204 CC · PPP1CB rs193167778 CC · PCDH9 rs369611135 TT
From your Joint & Tendon Health report
FTendon Inflammation
Less likely
Lower predisposition than 81% of people
TNP1 rs10203066 GG · LTBP3 rs4244811 GA · CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
FTendon Injury
Less likely
Lower predisposition than 82% of people
POLE2 rs3218791 GT · GJA1 rs11154027 CC · CERS5 rs57224706 AA
FJoint Pain
Less likely
Lower predisposition than 99% of people
SRR rs216175 AA · ERI1 rs330050 GG · LYZ rs317630 TT · DPEP1 rs1126464 GG · FAM53A rs798726 CT · ANAPC4 rs34811474 GA · TGFB2 rs2785988 CA · LTBP1 rs2061027 GA
FEhlers-Danlos Syndrome (Progeroid
Less likely
Lower predisposition than average
FADAMTS5 (Joint Health)
Better genetics
Lower predisposition than average
ADAMTS5 rs2249350 AC · ADAMTS5 rs229052 AG · ADAMTS5 rs162502 TC · ADAMTS5 rs151058 CT · ADAMTS5 rs3171407 CC · ADAMTS5 rs229077 TT · ADAMTS5 rs229071 AA · ADAMTS5 rs162509 CC
In line with most people  (23)Nothing unusual. These were tested and came back typical — worth having on record.
From your Bone Health report
·Bone Infection
Typical likelihood
In line with the general population · 65th percentile
·Spinal Canal Narrowing
Typical likelihood
In line with the general population · 60th percentile
IPP rs2356581 AA · DYNC1I1 rs2051706 GG · TRIM32 rs1040851 CC · PDE3A rs7298820 AT · SMAD3 rs28613758 CT · SLITRK6 rs2183749 AC · ELMOD2 rs184579809 TT · HEY1 rs143958409 CC
·Fractures
Typical likelihood
In line with the general population · 37th percentile
MARCO rs115242848 CC · HLA-DQA1 rs2071805 CC · VARS2 rs9262558 CC · SP7 rs144680237 CC · CPED1 rs3779381 AA · ZBTB40 rs34414754 AA · WLS rs2566755 TT · NTNG1 rs76259395 AA
·Osteoporosis
Typical likelihood
In line with the general population · 33th percentile
MARCO rs115242848 CC · COPB1 rs10741657 GG · CPNE1 rs143383 AA · CPED1 rs3779381 AA · ZBTB40 rs34414754 AA · WLS rs2566755 TT · CPED1 rs10242100 AA · FKBP11 rs3741619 GA
·Hyperparathyroidism
Typical likelihood
In line with the general population
FIBIN rs375264315 CC · MRPS31 rs141641942 CC · LRFN5 rs117828799 AG · MED13L rs139671128 GA · RASSF3 rs190001302 TT · SFTPA1 rs146467844 AA · TEX26 rs73165078 AA · HMX3 rs80212821 CC
·Vitamin D
Typical need
In line with the general population
COPB1 rs12794714 AA · COPB1 rs10832289 TT · GC rs2282679 GT · VDR rs2228570 GA · PDE3B rs571484036 AA · GC rs222026 TT · GC rs4588 TG · VDR rs731236 AG
·Phosphate
Typical levels
In line with the general population
NBPF3 rs1697421 TC · IP6K3 rs9469578 CC · C12ORF4 rs2970818 TT · AHI1 rs947583 TT · CSTA rs17265703 AA
·Magnesium
Typical need
In line with the general population
TRPM6 rs11144134 TT · VIPR1 rs11718502 TC · THBS3 rs4072037 TC · PAPSS2 rs791888 GG · RALGDS rs7032317 CT · CDKL2 rs6838240 CT · ALPK1 rs2074379 AG · C8ORF48 rs10888073 CT
·VDR (Vitamin D)
Typical activity
In line with the general population
VDR rs2228570 GA · VDR rs1544410 CT · VDR rs7975232 AA
·CYP2R1 (Vitamin D)
Typical activity
In line with the general population
COPB1 rs10741657 GG · COPB1 rs10766197 AA
From your Joint & Tendon Health report
·Achilles Tendon Injury
Typical likelihood
In line with the general population · 79th percentile
COL1A1 rs1800012 AC · MMP1 rs591058 CC · VEGFA rs699947 AC · FCN2 rs1134170 TT · COL5A1 rs12722 TC · TMEM158 rs183364169 CC · DPP6 rs4067493 CC · TRIML1 rs60713544 GG
·Hip Pain
Typical likelihood
In line with the general population · 64th percentile
KAZN rs549908604 AA · HIPK1 rs149055514 AA · PBX1 rs506068 CC · PGLYRP3 rs117034852 TT · SEMA4A rs531735825 CC · FNDC7 rs181938434 GG · PGLYRP3 rs118113194 CC · KIAA1614 rs144390511 CC
·Gout
Typical likelihood
In line with the general population · 58th percentile
SLC2A9 rs16890979 CC · SLC2A9 rs6449213 TT · SLC2A9 rs12498742 AA · SPP1 rs2728127 AA · TMEM171 rs520007 CC · TRMT112 rs2078267 TC · GCKR rs1260326 TC · MTX1 rs760077 TA
·Carpal Tunnel Syndrome
Typical likelihood
In line with the general population · 56th percentile
UMPS rs4678145 GG · LNPK rs847139 CC · EFEMP1 rs3791679 AG · ADAMTS14 rs747141 GA · TBX18 rs62422907 AG · TNP1 rs1863190 TA · AEBP1 rs55841377 CG · AOC1 rs6977081 TG
·Rheumatoid Arthritis
Typical likelihood
In line with the general population · 40th percentile
HLA-DQA2 rs6457617 TC · CTLA4 rs3087243 GG · ANKRD55 rs7731626 GG · ETS1 rs73013527 CC · RUNX1 rs8133843 AA · LBH rs7579944 CC · PODXL rs11761231 CC · ARID5B rs71508903 CT
·Joint Stiffness
Typical likelihood
In line with the general population · 39th percentile
·Knee Pain
Typical likelihood
In line with the general population · 36th percentile
COL27A1 rs919642 AA · EPHA5 rs201194999 CC · COL11A1 rs2622873 TT · ICA1L rs62182810 AA · BRINP3 rs72727240 TT · MAB21L3 rs79678808 AA · CDC42BPA rs56339347 AA · CDC42BPA rs573881227 CC
·Tendon Lining Inflammation
Typical likelihood
In line with the general population · 36th percentile
CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
·Lupus
Typical likelihood
In line with the general population · 12th percentile
IRF8 rs11644034 GG · NADSYN1 rs3794060 CC · PRDM1 rs6568431 AA · IKZF1 rs4917014 TT · LYST rs9782955 CC · ZFP36L1 rs4902562 AA · UBE2L3 rs7444 CT · SLU7 rs2431697 TC
·Psoriatic Arthritis
Typical likelihood
In line with the general population
TYK2 rs34536443 GG · MICB rs13191343 TC · IL12B rs4921482 TT · STAT2 rs2020854 TT · IL12B rs62377586 GG · SLC22A5 rs848 CC · NXPE3 rs4683946 GG · CNTN4 rs17194140 TT
·Rheumatic Fever
Typical likelihood
In line with the general population
·Ankylosing Spondylitis
Typical likelihood
In line with the general population
IL23R rs11209026 GG · ERAP2 rs10045403 AA · NKX2-3 rs11190133 CC · ERAP1 rs30187 CT · CARD9 rs1128905 CC · INAVA rs41299637 TG · ETS2 rs2836883 AG · ERAP2 rs2910686 CT
·COL5A1 (Collagen)
Typical activity
In line with the general population
COL5A1 rs12722 TC

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-31B9E0
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-31B9E0 · © 2026 Marrow Health.