Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 5 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Brain Health82 results reported of 91 analytes · 50 recommendations
Cognition28 results reported of 34 analytes · 50 recommendations
Mood & Mental Health62 results reported of 65 analytes · 50 recommendations
Nerve Health30 results reported of 36 analytes · 50 recommendations
Headaches & Migraines5 results reported of 5 analytes · 50 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 121 results here, 25 came back worth discussing with a clinician and 7 came back in your favour. Bring this document to your appointment.
What this package looks at
Brain Health — Some of us get stressed out by every single detail, while others go through life with a smile on their face. Going out for a drink after work, one has a single glass, while another downs an entire bottle. In a college class, one student pours through a text, while another googles up possible places to
Cognition — Cognition, or the mental processes involved in acquiring knowledge and understanding, is a critical aspect of human functioning. From problem-solving and memory to creativity and reasoning, our cognitive abilities shape how we navigate the world.
Mood & Mental Health — Mental health and mood regulation are influenced by a combination of environmental factors and genetics. Recent advances in genetic research have unveiled how specific genes and biomarkers may predispose individuals to various mental health conditions, mood disorders, and
Nerve Health — Nerve health plays a vital role in overall well-being, affecting everything from movement and sensation to cognition and emotional balance. Genetics can significantly influence an individual's susceptibility to various nerve-related conditions, impacting both the peripheral and central
Headaches & Migraines — Headaches and migraines are common issues that can significantly impact daily life, leading to discomfort, pain, and reduced productivity. While environmental factors such as stress, sleep patterns, and diet can trigger headaches, genetics also plays an essential role in determining an
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Sleep for 7+ HoursEnsure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
Relates to: Brain Fog, Short-Term Memory Impairment, Migraines, Cluster Headaches
2
Cognitive-Behavioral Therapy (CBT)Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Relates to: Low Mood, CRHR2 (Stress/HPA Axis), MAOA (Dopamine/Serotonin), Obsessive-Compulsive Tendencies
3
PsychotherapySchedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Relates to: Bipolar Disorder, Low Mood, Obsessive-Compulsive Tendencies, Psychological Trauma
4
Interpersonal Therapy50 minutesEngage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.
Relates to: Low Mood, Eating Disorders
5
Psychodynamic TherapyPsychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
Relates to: Low Mood, Psychological Trauma, Eating Disorders, Anger
6
Avoid Food TriggersTry to limit caffeine to per day to avoid migraines.
Relates to: Migraines
7
Avoid Sensory TriggersPractice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
Relates to: Migraines
8
Sunlight Exposure20 minutesExpose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.
Relates to: Low Mood, Bipolar Disorder, DRD2 (Dopamine), RGS2 (Anxiety)
9
Strength TrainingEngage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
Relates to: Parkinson's Disease, Diabetic Neuropathy
10
Nerve Stimulation30 minutesNerve stimulation can be implemented by daily sessions of 15-30 minutes using a device specifically designed for TA this purpose.
Relates to: Cluster Headaches, Migraines
11
CoffeeDrink 1 to 3 cups of black coffee daily, preferably in the morning to minimize potential sleep disturbances.
Relates to: Brain Fog, Parkinson's Disease, Short-Term Memory Impairment
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
St. John's WortRelates to: Low Mood, DRD2 (Dopamine), Short-Term Memory Impairment, Obsessive-Compulsive Tendencies
2
MagnesiumRelates to: Migraines, Cluster Headaches
3
TryptophanRelates to: Low Mood, MAOB (Dopamine/ Norepinephrine), Bipolar Disorder, Mania
Your headline findings
Of the 121 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
ManiaMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
What this actually is
Risk factors for mania include: Bipolar disorder Family history Stress Drug use Sleep deprivation More likely to genetic Treating mania typically involves a combination of medication, psychotherapy, and lifestyle adjustments.
Mood stabilizers such as lithium, anticonvulsants like valproate or carbamazepine, and atypical antipsychotics are often prescribed to manage manic episodes and prevent their recurrence.
Psychotherapy, particularly cognitive-behavioral therapy (CBT) or psychoeducation, can help individuals recognize triggers, Your risk develop coping strategies, and improve insight into their and condition.
What you can do
- Avoid Cadmium Exposure
Consider increasing your intake of tryptophan-rich foods. - Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Brain Health report & Mood & Mental Health
Eating DisordersMore likely
More likely to have an eating disorder based on 11,026 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Other risk factors include dieting, major stressful events, and other mental health conditions.
If you have symptoms, talk to a healthcare professional.
About 1% of people may develop an eating disorder at some point in their life.
What you can do
- Psychotherapy
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress. - Gentle Yoga 20 minutes
Practice yoga for at least 20 to 30 minutes a day, most days of the week. - Morning Bright Light Therapy 20 minutes
Expose yourself to a light therapy box, which mimics natural sunlight, for about 20-30 minutes each morning TA within the first hour of waking up.
From your Brain Health report & Mood & Mental Health
MigrainesMore likely
More likely to have migraines based on 109,603 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Risk factors include: obesity, depression, stress, being female, blood vessel issues, brain chemical imbalances.
If you have a high genetic risk, take action on modifiable risk factors to help reduce overall risk.
About 16% of Americans regularly have migraines.
What you can do
- Avoid Food Triggers
Try to limit caffeine to per day to avoid migraines. - Avoid Sensory Triggers
Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition. - Sleep for 7+ Hours
Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
From your Headaches & Migraines report
Binge EatingMore likely
More likely to binge eat based on 13,449 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Binge eating can be associated with: Psychological issues: Low self-esteem, body dissatisfaction, and significant stress can trigger binge eating.
Biological factors: Genetic mutations may affect hunger and satiety, through alterations in brain chemistry that can predispose individuals to eating disorders.
Social and cultural factors: Dysfunctional family dynamics, professions and activities that focus on appearance and dieting, and traumatic situations such as bullying or abuse can increase the risk of BED.
What you can do
- Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life. - Psychodynamic Therapy
Psychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
From your Brain Health report & Mood & Mental Health
Facial PainMore likely
Higher predisposition than 98% of people
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Diagnosing facial approach that can otolaryngologists, comprehensively and strategies could blocks, or surgery, For instance, sudden, severe resulting from Psychological also play pivotal the need for a plan.
What you can do
- Avoid Phthalate Exposure
Aim to make these changes consistently in your daily life for long-term health benefits.
From your Nerve Health report
Brain FogMore likely
More likely to have brain fog based on 5,554 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Key Takeaways: Brain fog is a common symptom of chronic fatigue syndrome.
It manifests as memory problems, difficulty focusing, jumbled or hazy thoughts, and confusion.
Risk factors include stress, sleep problems, air pollution, smoking, and your genetics.
What you can do
- Sleep for 7+ Hours
Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night. - Coffee
Drink 1 to 3 cups of black coffee daily, preferably in the morning to minimize potential sleep disturbances. - Cognitive Training 15 minutes
Engage in exercises that challenge your brain for at least 15 minutes per day, five days a week.
From your Brain Health report & Cognition
Droopy EyelidsMore likely
More likely to have droopy eyelids based on 240,468 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Eyelid drooping is excess sagging of the upper eyelid.
The eyelid may be sitting lower than it should (ptosis) or drooping due to loose or excess skin (dermatochalasis).
About 60% of the differences in people’s eyelid drooping may be due to genetics.
From your Nerve Health report
Guilty FeelingsMore likely
More likely to have guilty feelings based on 508,257 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.
What this actually is
Chronic or excessive feelings of guilt can be particularly debilitating, leading to a well-documented decline in psychological well-being.
It can manifest in physical symptoms such as insomnia, loss of appetite, or gastrointestinal distress due to the close connection between mental and physical health.
In some cases, persistent guilt may also contribute to the development of mental health conditions such as depression, anxiety disorders, and compulsive behaviors.
From your Brain Health report & Mood & Mental Health
A further 17 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.
About 60-70% of the differences in people’s cognitive decline may come from genetics.
For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].
From your Brain Health report & Cognition, Nerve Health
Speech DisorderLess likely
Lower predisposition than 86% of people
Your result sits lower than 86% of the population.
What this actually is
Living with aphasia can be challenging, not only for those affected but also for their family and friends.
It often leads to social isolation and frustration due to the barriers it creates in everyday communication.
Therapy for aphasia primarily involves speech and language exercises that aim to improve the individual's ability to Less likely to have communicate.
From your Nerve Health report
DeliriumLess likely
Lower predisposition than average
From your Brain Health report & Mood & Mental Health
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (17)
- Dyslexia — More likely, 96th percentile
- Borderline Personality — More likely, 93th percentile
- Obsessive-Compulsive Tendencies — More likely, 92th percentile
- Psychological Trauma — More likely, 90th percentile
- Anger — More likely, 90th percentile
- Agoraphobia — More likely, 88th percentile
- Low Mood — More likely, 85th percentile
- Tremor — More likely, 82th percentile
- Cluster Headaches — More likely, 82th percentile
- Tobacco Addiction — More likely, 80th percentile
- Bipolar Disorder — More likely, 75th percentile
- Parkinson's Disease — More likely, 70th percentile
- Emotional Blindness — More likely
- Short-Term Memory Impairment — More likely
- GAD1 (Glutamate/GABA) — Worse
- NPAS2 (Mood/ Sleep Schedule) — Worse genetics
- Diabetic Neuropathy — More likely
Running above the typical range (9)
- Irritability — Higher, 95th percentile
- MAOA (Dopamine/Serotonin) — Higher activity
- MAOB (Dopamine/ Norepinephrine) — Higher activity
- DRD3 (Dopamine/Energy) — Higher activity
- HTR1A (Serotonin) — Higher activity
- OXTR (Oxytocin) — Higher activity
- TUSC3 (Cognition) — Higher activity
- KIBRA/WWC1 (Cognition) — Higher activity
- TRPM8 (Pain) — Higher activity
Running below the typical range (11)
- TRPV1 (Pain) — Lower activity, 15th percentile
- GABA-A — Lower activity
- CRHR2 (Stress/HPA Axis) — Lower activity
- DRD2 (Dopamine) — Lower activity
- RGS2 (Anxiety) — Lower activity
- FAAH (Cannabinoids) — Lower activity
- CRHR1 (Stress/HPA Axis) — Lower activity
- FKBP5 (Stress/ HPA Axis) — Lower activity
- SOAT1 (Cholesterol/ Cognition) — Lower activity
- SLC6A4 (Fatigue, Mental Health) — Lower activity
- ENPP6 (Cognition) — Lower activity
Working in your favour (4)
- Anhedonia — Less likely
- Neurodivergence — Less likely
- Caffeine-Related Anxiety — Less likely
- Episodic Memory — Better
In line with most people (69)
- Teeth Grinding — Typical likelihood, 74th percentile
- Hair Pulling — Typical likelihood, 74th percentile
- Stress — Typical likelihood, 74th percentile
- Phobias — Typical likelihood, 74th percentile
- Worrying — Typical likelihood, 70th percentile
- Trigeminal Nerve Pain — Typical likelihood, 68th percentile
- Seasonal Low Mood — Typical likelihood, 65th percentile
- Alzheimer's Disease — Typical likelihood, 65th percentile
- Tension Headaches — Typical likelihood, 64th percentile
- Schizophrenia — Typical likelihood, 63th percentile
- Stroke — Typical likelihood, 63th percentile
- Addiction — Typical likelihood, 62th percentile
- Burning Mouth Syndrome — Typical likelihood, 62th percentile
- Multiple Sclerosis — Typical likelihood, 60th percentile
- Anxiety — Typical likelihood, 57th percentile
- Panic Attacks — Typical likelihood, 57th percentile
- Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
- Headache — Typical likelihood, 51th percentile
- SNAP25 (Mental Health) — Typical activity, 50th percentile
- Dementia — Typical likelihood, 48th percentile
- Alcohol Addiction — Typical likelihood, 48th percentile
- Psychosis — Typical likelihood, 46th percentile
- Aggression — Typical, 46th percentile
- Difficulty Swallowing — Typical likelihood, 43th percentile
- Attention — Typical, 39th percentile
- Social Anxiety — Typical likelihood, 37th percentile
- Tics — Typical likelihood, 33th percentile
- Amnesia — Typical likelihood, 30th percentile
- Paresthesia — Typical likelihood, 23th percentile
- Nerve Compression — Typical likelihood, 22th percentile
- Cannabis Addiction — Typical likelihood, 20th percentile
- Nail Biting — Typical likelihood
- Nervousness — Typical
- Response to Stress (Functional) — Typical response
- Cortisol — Typical levels
- Executive Function — Typical
- Processing Speed — Typical
- Memory Performance — Typical
- Creativity — Typical
- Cognitive Function — Typical
- Reaction Time — Typical
- Verbal Ability — Typical
- Problem Solving — Typical ability
- GSK3B (Serotonin) — Typical activity
- HTR2A (Serotonin) — Typical activity
- TPH2 (Serotonin) — Typical activity
- CNR1 (Cannabinoids) — Typical activity
- GRIA3 (Sleep/Mood) — Typical activity
- ADORA2A (Anxiety) — Typical activity
- COMT — Typical activity
- NFKBIL1 (Cognition) — Typical activity
- TNFSF9 (Cognition) — Typical activity
- TF (Iron & Cognition) — Typical activity
- PARP1 (Longevity, Cognition) — Typical genetics
- CHRNA5 (Smoking, Cognition) — Typical activity
- LMX1A (Cognition) — Typical activity
- SLC6A2 (Mental Health) — Typical activity
- DBH (Mental Health) — Typical activity
- SLC6A3 (Mental Health) — Typical activity
- Brain Cancer — Typical likelihood
- Brain Ischemia — Typical likelihood
- Dystonia — Typical likelihood
- Seizures — Typical likelihood
- Neuropathic Pain — Typical likelihood
- Peripheral Neuropathy — Typical likelihood
- Bell's Palsy — Typical likelihood
- IDO (Kynurenine) — Typical levels
- SCN9A (Pain) — Typical activity
- DAO (Histamine) — Typical activity
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.