Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 3 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Cardiovascular Health82 results reported of 88 analytes · 50 recommendations
Kidney Health22 results reported of 23 analytes · 50 recommendations
Inflammation & Autoimmunity80 results reported of 83 analytes · 50 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 180 results here, 26 came back worth discussing with a clinician and 8 came back in your favour. Bring this document to your appointment.
What this package looks at
Cardiovascular Health — “Oh, my god! That will give you a heart attack!” said every cliche grandmother ever written. There is a notoriously long list for what “that” is, from high cholesterol to stress to weight. Unfortunately, people have a tendency to not worry about a health issue until it becomes a problem. So,
Kidney Health — The kidneys play a vital role in filtering waste and maintaining fluid and electrolyte balance in the body. Genetic factors can influence your susceptibility to various kidney-related conditions, ranging from chronic diseases to acute kidney injuries.
Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Mediterranean DietLimit red meat to a few times a month and include a moderate amount of dairy products.
Relates to: Coronary Artery Disease, Artery Hardening, Peripheral Artery Disease, ApoB
2
Avoid DioxinReduce consumption of animal fats, since dioxins accumulate in fat tissue.
Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
3
Limit Salt IntakeBy limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
4
Choose Healthy FatsAim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.
Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Lipoprotein(a)
5
Reduce Oxalate IntakeAvoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
6
Walking30 minutesIncorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
Relates to: Coronary Artery Disease, Peripheral Artery Disease, Artery Hardening, ApoB
7
Whole-Food Plant-Based Dietfew weeks to avoid digestive discomfort.
Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
8
Limit Protein IntakeLimit your daily protein intake to per kilogram of your body weight.
Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD)
9
Avoid Secondhand SmokeAvoid Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.
Relates to: Coronary Artery Disease, Artery Hardening, ApoB, Homocysteine
10
Sleep for 7+ HoursEnsure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
Relates to: Coronary Artery Disease, Heart Rate Recovery, Artery Hardening, ApoB
11
Limit Saturated FatReduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.
Relates to: Artery Hardening, Peripheral Artery Disease, Coronary Artery Disease, Lipoprotein(a)
12
Stair Climbing10 minutesAim for at least 10 minutes of continuous stair climbing or multiple shorter sessions that add up to 10 minutes per day.
Relates to: Coronary Artery Disease, Artery Hardening
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
MethylfolateRelates to: Homocysteine, Retinal Vein Occlusion, Coronary Artery Disease, Artery Hardening
2
Dietary Omega-3 Fatty AcidsRelates to: Heart Failure, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
Your headline findings
Of the 180 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Varicose VeinsMore likely
More likely to have varicose veins based on 81,137 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Risk factors include: age, being female, overweight, sitting or standing most of the day, pregnancy, and childbirth.
If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.
Normal, healthy veins have many valves that keep the blood flowing in the right direction.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Apples
Incorporate at least one whole apple into your daily diet, either as a snack or part of your meals, ensuring to eat them consistently every day for an ongoing period to derive potential health benefits.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Cardiovascular Health report
Blood SpotsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
From your Cardiovascular Health report
PalpitationsMore likely
More likely to have palpitations based on 1,209,944 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: While no heritability percentage exists yet for this condition, genes involved may influence various heart functions.
Other risk factors include stress, anxiety, pregnancy, age, stimulants, overactive thyroid, and heart problems.
Experiencing palpitations are not uncommon, particularly because they can result from causes unrelated to heart conditions, like anxiety.
From your Cardiovascular Health report
Low Blood PressureMore likely
More likely to have low blood pressure based on 54,555 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: Genetics may play a role by influencing nervous system function, kidney function, and hormone activity.
Other risk factors include certain medications and health conditions.
It is estimated that up to 25% of adults may have low blood pressure.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Hazelnuts
Incorporate a handful of hazelnuts (about or) into your diet daily.
From your Cardiovascular Health report
Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.
Ask your clinician about
- Maintain Optimal Vitamin D Levels
- Zinc
Named only. Marrow gives no dose and does not recommend these.
From your Inflammation & Autoimmunity report
Kidney StonesMore likely
More likey to have kidney stones based on 816,639 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Key Takeaways: About 50% of differences in people's chances of developing kidney stones may be due to genetics.
Risk factors include dehydration, excess animal protein, salt, or sugar, obesity, IBD, UTIs, medications, excess vitamin C.
About 11% of American men and 7% of women have kidney stones.
What you can do
- Avoid Dioxin
Reduce consumption of animal fats, since dioxins accumulate in fat tissue. - Limit Salt Intake
By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling. - Reduce Oxalate Intake
Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Renal ColicMore likely
More likely to have a renal colic based on 437,591 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Renal colic can be who have a history stones, such as underlying their formation. nonsteroidal necessary.
Hydration is cases, medical stone removal may large to pass or complications.
What you can do
- Avoid Dioxin
Reduce consumption of animal fats, since dioxins accumulate in fat tissue. - Limit Salt Intake
By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling. - Reduce Oxalate Intake
Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.
What this actually is
The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.
Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.
Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.
What you can do
- Autoimmune Protocol (AIP) Diet
Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.
Ask your clinician about
- Maintain Optimal Vitamin D Levels
Named only. Marrow gives no dose and does not recommend these.
From your Inflammation & Autoimmunity report
A further 18 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.
A history of diabetes in one's family.
A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.
From your Cardiovascular Health report
Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Risk factors include being under age 30, European ancestry, and smoking.
IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.
IBD only affects about 3 in 1000 people worldwide.
From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Other risk factors include being young and male.
is not rare, happening to about 7-8% of people in their lifetime.
If your genetic risk is high, know the symptoms and seek medical attention if you have them.
From your Inflammation & Autoimmunity report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (18)
- Artery Hardening — More likely, 95th percentile
- Pancreas Inflammation — More likely, 95th percentile
- Acute Kidney Injury — More likely, 93th percentile
- Retinal Vein Occlusion — More likely, 90th percentile
- Urethra Inflammation — More likely, 88th percentile
- Eye Inflammation — More likely, 84th percentile
- Coronary Artery Disease — More likely, 67th percentile
- Crohn’s Disease — More likely, 66th percentile
- Psoriasis — More likely, 65th percentile
- Heart Failure — More likely
- Myocarditis — More likely
- Subarachnoid Hemorrhage — More likely
- Brain Hemorrhage — More likely
- Peripheral Artery Disease — More likely
- Polycystic Kidney Disease — More likely
- Kidney Failure (ESRD) — More likely
- Nephritis — More likely
- Diabetic Nephropathy — More likely
Running above the typical range (23)
- ApoB — Higher levels, 99th percentile
- ADRB1 (Cardiovascular) — Higher activity, 92th percentile
- IRS1 (Metabolic Health) — Higher activity, 85th percentile
- Lipoprotein(a) — Higher levels, 81th percentile
- HLA (Inflammation) — Higher activity, 80th percentile
- Heart Rate Variability — Higher
- PCSK9 (Cholesterol) — Higher activity
- CELSR2-PSRC1-SORT1 (Cardiovascular) — Higher activity
- AGT (Cardiovascular & Fitness) — Higher activity
- GCH1 (Cardiovascular) — Higher activity
- LIPC (Cardiovascular) — Higher activity
- TMAO — Higher levels
- Homocysteine — Higher levels
- Platelet Aggregation — Higher
- Albumin — Higher levels
- GRHPR (Oxalate & Kidneys) — Higher activity
- Basophils — Higher levels
- HLA-DOB (Inflammation) — Higher activity
- NF-kB (Inflammation) — Higher activity
- NLRP3 (Gut Inflammation) — Higher activity
- ANKRD55 (Autoimmune) — Higher activity
- ABCB1 (Chronic Lyme) — Higher activity
- HNMT (Histamine) — Higher activity
Running below the typical range (15)
- Heart Rate Recovery — Slower
- CPS1 (Cardiovascular, Kidney Health) — Lower activity
- DOCK7 (Blood Lipids) — Lower activity
- FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
- CETP (Cholesterol/ Longevity) — Lower activity
- ACE (Fitness/ Cardiovascular) — Lower activity
- MLXIPL (Triglycerides, Cardiovascular) — Lower activity
- SOAT1 (Cholesterol/ Cognition) — Lower activity
- SH2B3 (Autoimmunity) — Lower activity
- HNF4A (Gut Inflammation) — Lower activity
- CTLA4 (Autoimmunity) — Lower activity
- IL1B (Inflammation/ Fatigue) — Lower activity
- JAK2 (Gut Inflammation) — Lower activity
- IL8 (Inflammation) — Lower activity
- IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour (5)
- Optic Nerve Inflammation — Less likely, 19th percentile
- Mitral Valve Prolapse — Less likely
- Diverticular Disease — Less likely
- Sjogren's Syndrome — Less likely
- IL6R (Weight) — Better genetics
In line with most people (108)
- Peripheral Vascular Disease — Typical likelihood, 98th percentile
- Chronic Venous Insufficiency — Typical likelihood, 85th percentile
- Heart Arrhythmia — Typical likelihood, 67th percentile
- POTS — Typical likelihood, 65th percentile
- VLDL Cholesterol — Typical levels, 65th percentile
- Stroke — Typical likelihood, 63th percentile
- Ulcerative Colitis — Typical likelihood, 63th percentile
- Venous Thromboembolism — Typical likelihood, 61th percentile
- Total Cholesterol — Typical levels, 61th percentile
- Cardiovascular Disease — Typical likelihood, 60th percentile
- Multiple Sclerosis — Typical likelihood, 60th percentile
- Chest Pain (Angina) — Typical likelihood, 52th percentile
- Blood Clotting — Typical likelihood, 52th percentile
- High Blood Pressure — Typical likelihood, 51th percentile
- LDL Particle Number (LDL-P) — Typical, 47th percentile
- High Cholesterol — Typical likelihood, 46th percentile
- LDL Cholesterol — Typical levels, 44th percentile
- Kidney Problems — Typical likelihood, 44th percentile
- Stomach Inflammation — Typical likelihood, 42th percentile
- Celiac Disease — Typical likelihood, 42th percentile
- Rheumatoid Arthritis — Typical likelihood, 40th percentile
- Atrial Fibrillation — Typical likelihood, 39th percentile
- HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
- Inflammation (CRP) — Typical levels, 36th percentile
- Cold Hands and Feet (Raynaud's) — Typical likelihood, 31th percentile
- Eczema — Typical likelihood, 29th percentile
- IL-6 — Typical levels, 20th percentile
- Uric Acid — Typical levels, 16th percentile
- Type 1 Diabetes — Typical likelihood, 15th percentile
- Lupus — Typical likelihood, 12th percentile
- Heart Attack — Typical likelihood
- Rheumatic Heart Disease — Typical likelihood
- Aortic Stenosis — Typical likelihood
- Dilated Cardiomyopathy — Typical likelihood
- Hypertrophic Cardiomyopathy — Typical likelihood
- Aortic Valve Calcification — Typical likelihood
- Aortic Aneurysm — Typical likelihood
- Brain Aneurysm — Typical likelihood
- Cerebral Small Vessel Disease — Typical likelihood
- Brain Ischemia — Typical likelihood
- Vasculitis — Typical likelihood
- Deep Vein Thrombosis — Typical likelihood
- Heart Rate — Typical
- Tachycardia — Typical likelihood
- Bradycardia — Typical likelihood
- Salt Sensitivity — Typical
- Pulmonary Hypertension — Typical likelihood
- APOC3 (Blood Lipids/ Longevity) — Typical activity
- NOS3 (Cardiovascular) — Typical activity
- HMGCR (Cholesterol) — Typical activity
- APOA2 (Weight, Blood Lipids) — Typical activity
- APOB Gene (Cardiovascular) — Typical activity
- ABCA1 (Cholesterol) — Typical genetics
- LPA (Blood Lipids & Heart Health) — Typical activity
- LDLR (Cholesterol, Cardiovascular) — Typical activity
- LDL Particle Size — Typical
- Lp-PLA2 — Typical levels
- Platelets — Typical levels
- Response to Ezetimibe — Typical
- Response to Statins (Functional) — Typical response
- IgA Nephropathy — Typical likelihood
- Contrast-Induced Nephropathy — Typical likelihood
- eGFR — Typical levels
- Creatinine — Typical levels
- Blood Urea Nitrogen (BUN) — Typical levels
- Sodium — Typical levels
- Total Protein — Typical levels
- Cystatin C — Typical levels
- Potassium — Typical need
- Chloride — Typical levels
- Chronic Lyme — Typical likelihood
- Sepsis — Typical likelihood
- Pulmonary Fibrosis — Typical likelihood
- Actinic Keratosis — Typical likelihood
- Meningitis — Typical likelihood
- Sarcoidosis — Typical likelihood
- Rheumatic Fever — Typical likelihood
- Psoriatic Arthritis — Typical likelihood
- Ankylosing Spondylitis — Typical likelihood
- Vitiligo — Typical likelihood
- Alopecia Areata — Typical likelihood
- Systemic Sclerosis — Typical likelihood
- Pemphigus Vulgaris — Typical likelihood
- Behcet’s Disease — Typical likelihood
- TNF — Typical levels
- White Blood Cells — Typical levels
- Eosinophils — Typical levels
- Monocytes — Typical levels
- Neutrophils — Typical levels
- Erythrocyte Sedimentation Rate — Typical levels
- IgE — Typical levels
- IL-10 — Typical levels
- IL-17 (Th17) — Typical levels
- HLA-B (Autoimmune) — Typical
- HLA-DQ (Inflammation) — Typical activity
- HLA-DRB1 (Autoimmunity) — Typical
- HLA-DQA2 (Inflammation) — Typical
- TLR4 (Inflammation) — Typical activity
- PTPN22 (Autoimmunity) — Typical
- DAO (Histamine) — Typical activity
- STAT3 (Th1/Th17) — Typical activity
- TNF Gene (Inflammation) — Typical activity
- IL13 (Allergies, Lung Function) — Typical activity
- IL4 (Allergies, Autoimmunity) — Typical activity
- CRP Gene — Typical activity
- PADI4 (Autoimmune) — Typical activity
- IL10 Gene (Autoimmunity) — Typical activity
- SLC22A4 (Gut Inflammation) — Typical genetics
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.