Marrow
Genomics · Genetic Reports · Precision Wellness

Fertility & Reproductive Package

Personalized 4-Report Genetic Package
Fertility & Reproductive HealthFertilityHormone HealthSex Hormones
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-18B423
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-18B423
Reports in package
4
Results scored
74 of 105
Need attention
6
Report
Summary Report

The reports inside this package

This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Fertility & Reproductive Health30 results reported of 33 analytes · 49 recommendations
Fertility14 results reported of 14 analytes · 50 recommendations
Hormone Health46 results reported of 46 analytes · 50 recommendations
Sex Hormones12 results reported of 12 analytes · 47 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 74 results here, 6 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Fertility & Reproductive Health — Female reproductive health is influenced by a complex interaction of genetics, hormones, and environmental factors. Genetics plays a significant role in determining a woman's predisposition to fertility issues, menstrual cycle irregularities, and reproductive hormone imbalances.

Fertility — Male reproductive health is influenced by a combination of genetic, hormonal, and environmental factors. Genetics plays a significant role in determining fertility and the balance of reproductive hormones, both of which are crucial for reproductive function.

Hormone Health — Your hormonal (endocrine) system regulates body processes, such as appetite, sex drive, tissue repair, metabolism, and more. Hormones affect more or less everything in your body!

Sex Hormones — Sex hormones and reproductive hormones play vital roles in regulating physical development, reproductive function, and overall health. These hormones influence everything from muscle mass and bone density to fertility, libido, and mood. Genetic predispositions can affect how these

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Pesticide Exposure

Limit the use of non-organic lawn and garden chemicals.

Relates to: Male Infertility
relevance
2
Avoid Organic Solvents

Refrain from using products containing organic solvents such as paints, varnishes, paint strippers, cleaning supplies, glues, and adhesives.

Relates to: Male Infertility
relevance
3
Avoid PAHs Exposure

Use exhaust fans in kitchens and ensure proper ventilation when cooking at high temperatures to reduce indoor levels of PAHs.

Relates to: Male Infertility
relevance
4
Sleep for 7+ Hours

Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.

Relates to: Male Infertility
relevance
5
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Male Infertility
relevance
6
Tomato

Aim for at least one serving (approximately 1 medium-sized tomato or 1/2 cup of chopped or cooked tomatoes) per day.

Relates to: Male Infertility
relevance
7
Avoid Formaldehyde Exposure

Aim to reduce use of pressed wood products and seek out alternatives when possible.

Relates to: Miscarriage, Female Infertility, Male Infertility
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
DHEA (Dehydroepiandrosterone)
Relates to: DHEAS
relevance
2
Zinc
Relates to: Male Infertility
relevance
3
Zinc and Folate
Relates to: Male Infertility
relevance
4
Resistant Starch
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
5
Berberine
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
6
Inositol
Relates to: Male Infertility
relevance
7
Whey Protein
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance

Your headline findings

Of the 74 results in this package, these 6 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

MiscarriageMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The causes of is chromosomal pregnancy Hormonal to sustain the Immune system because the unwanted Uterine problems with from developing Infections: miscarriage.

Lifestyle and extreme to the risk.

Underlying diabetes, increase the Diagnosing a ultrasound, and levels.

What you can do

  • Avoid Formaldehyde Exposure
    Aim to reduce use of pressed wood products and seek out alternatives when possible.
  • Avoid Phthalate Exposure
    Avoid Phthalate To avoid phthalate exposure, check product labels and choose phthalate-free options for personal care items, plastics (look for recycling codes 3 and 7 or the letters 'V' or 'PVC'), and household products.
  • Avoid Mycotoxin
    Avoid Noise Pollution Minimize exposure to loud environments by using noise-cancelling headphones or earplugs, especially in areas known for high noise levels such as construction sites, concerts, and busy urban streets.
From your Fertility & Reproductive Health report
Abnormal Vaginal BleedingMore likely
More likely to have abnormal vaginal bleeding based on 66,937 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

The assessment of abnormal vaginal bleeding typically involves a detailed personal medical history and a physical examination, including pelvic examination.

Further diagnostic procedures might include ultrasounds, blood tests to check hormone levels, and sometimes a biopsy to rule out endometrial pathology.

Treatment options vary based on the cause and may include hormonal therapies, such as birth control pills or intrauterine devices (IUDs), medications to control bleeding, or surgical treatments.

What you can do

  • Avoid Douching
    Avoid Exposure To Organic Solvents Ensure to work in well-ventilated areas and wear protective gear when handling products like paints, varnishes, and adhesives.

Ask your clinician about

  • Black Cohosh

Named only. Marrow gives no dose and does not recommend these.

From your Fertility & Reproductive Health report
Male InfertilityMore likely
More likely to have male infertility based on 14,927 genetic variants we looked at
Your risk is greater than 86% of the population and lower than 14% of the population.

What this actually is

Key Takeaways: Genes affecting male fertility may be involved with sperm production and protecting DNA from damage.

Risk factors include: certain health or anatomical issues, stress, medical treatments, chemical/heat exposure, drug and alcohol use, smoking, obesity.

If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.

What you can do

  • Avoid Pesticide Exposure
    Limit the use of non-organic lawn and garden chemicals.
  • Avoid Organic Solvents
    Refrain from using products containing organic solvents such as paints, varnishes, paint strippers, cleaning supplies, glues, and adhesives.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Fertility report
Female InfertilityMore likely
More likely to have fertility problems based on 569 genetic variants we looked at
Your risk is greater than 85% of the population and lower than 15% of the population.

What this actually is

Key Takeaways: Genes affecting fertility may impact puberty and menopause.

Even without heritability numbers, managing risk factors like diet and not smoking, can help mitigate your overall risk.

Risk factors include age, smoking, over/underweight, past sexually transmitted infections, alcohol use, and PCOS.

What you can do

  • Avoid Formaldehyde Exposure
    Aim to reduce use of pressed wood products and seek out alternatives when possible.
  • Avoid Phthalate Exposure
    Avoid Phthalate To avoid phthalate exposure, check product labels and choose phthalate-free options for personal care items, plastics (look for recycling codes 3 and 7 or the letters 'V' or 'PVC'), and household products.

Ask your clinician about

  • Black Cohosh

Named only. Marrow gives no dose and does not recommend these.

From your Fertility & Reproductive Health report
Uterine FibroidsMore likely
More likely to have uterine fibroids based on 49 genetic variants we looked at
Your risk is greater than 82% of the population and lower than 18% of the population.

What this actually is

Uterine fibroids are benign growths that develop in the walls of the uterus.

They can vary in size – some are so small that they can’t be seen by the human eye, while others are so large that they can alter the shape of the uterus [R, R].

In the US, 70-80% of women may be diagnosed with uterine fibroids before they turn 50 [R, R, R].

What you can do

  • Avoid Rapid Weight Changes
    Maintain a consistent, healthy weight by avoiding extreme dieting or sudden increases in food intake.
From your Fertility & Reproductive Health report
TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average

What this actually is

The two main TCF7L2 variants are rs7903146 and rs12255372.

They are almost always inherited together, which means they act as a single genetic factor.

Their "T" alleles have one of the strongest known links with type 2 diabetes.

Ask your clinician about

  • Resistant Starch
  • Berberine
  • Whey Protein

Named only. Marrow gives no dose and does not recommend these.

From your Hormone Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Ovarian CystsLess likely
Less likely to have ovarian cysts based on 1,670 genetic variants we looked at
Your risk is greater than 3% of the population and lower than 97% of the population.

What this actually is

Factors that might increase the risk of developing ovarian cysts include: Hormonal imbalances, like those caused by polycystic ovary syndrome (PCOS).

Early menstruation onset, typically before age 11.

Pelvic infections that spread to the ovaries.

From your Fertility & Reproductive Health report
Preterm LaborLess likely
Less likely to give birth to a preterm baby based on 1,017,185 genetic variants we looked at
Your risk is greater than 14% of the population and lower than 86% of the population.

What this actually is

The exact causes of preterm labor can be difficult to pinpoint, but several factors are known to increase the risk: Multiple pregnancies: Twins, triplets, or higher-order multiples are more likely to be born prematurely.

Previous preterm birth Maternal health issues such as diabetes, high blood pressure, infections, and chronic conditions like heart and kidney disease Pregnancy complications: like preeclampsia, placental problems (e.g., placenta previa), or intrauterine growth restriction Smoking, alcohol use, and illicit drug use during pregnancy.

From your Fertility & Reproductive Health report
Heavy PeriodsLess likely
Less likely to have heavy periods based on 20,302 genetic variants we looked at
Your risk is greater than 17% of the population and lower than 83% of the population.

What this actually is

Other risk factors include certain medications and health conditions, use of intrauterine devices (IUD), and stress.

Up to 55% of people who menstruate may have heavy periods.

If you have high genetic risk or experience symptoms, talk to your healthcare professional about the best actions to take.

From your Fertility & Reproductive Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (11)
  • Testosterone (F) — Higher levels
  • FSH — Higher levels
  • Estradiol — Higher levels
  • SHBG — Higher levels
  • Estradiol (M) — Higher levels
  • Testosterone — Higher levels
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • DIO1 (Thyroid) — Higher activity
  • DIO2 (Thyroid) — Higher activity
  • GHR — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
Running below the typical range  (8)
  • Luteinizing Hormone (LH) — Lower levels
  • Prolactin — Lower levels
  • DHEAS — Lower levels
  • Pregnenolone — Lower levels
  • GLP-1 — Lower levels
  • CRHR2 (Stress/HPA Axis) — Lower activity
  • CRHR1 (Stress/HPA Axis) — Lower activity
  • FKBP5 (Stress/ HPA Axis) — Lower activity
Working in your favour  (3)
  • Preeclampsia — Less likely
  • Gestational Diabetes — Less likely
  • Testicular Cancer — Less likely
In line with most people  (43)
  • Stillbirth — Typical likelihood, 74th percentile
  • Pelvic Inflammatory Disease — Typical likelihood, 66th percentile
  • Ectopic Pregnancy — Typical likelihood, 59th percentile
  • PCOS — Typical likelihood, 47th percentile
  • Hashimoto's Disease — Typical likelihood, 47th percentile
  • Endometriosis — Typical likelihood, 46th percentile
  • Overactive Thyroid — Typical likelihood, 46th percentile
  • Low Sperm Count — Typical likelihood, 38th percentile
  • Irregular Periods — Typical likelihood, 36th percentile
  • Underactive Thyroid — Typical likelihood, 34th percentile
  • Pelvic Organ Prolapse — Typical likelihood
  • Ovarian Cancer — Typical likelihood
  • Endometrial Cancer — Typical likelihood
  • Cervical Cancer — Typical likelihood
  • Hyperemesis Gravidarum — Typical likelihood
  • Postpartum Depression — Typical likelihood
  • Bioavailable Testosterone (F) — Typical levels
  • Progesterone — Typical levels
  • ESR1 (Estrogen) — Typical activity
  • Sperm Motility — Typical
  • Bioavailable Testosterone — Typical levels
  • DHT — Typical levels
  • Free T4 — Typical levels
  • T3 (Triiodothyronine) — Typical levels
  • T4 (Thyroxine) — Typical levels
  • TSH — Typical levels
  • Graves' Disease — Typical likelihood
  • Reverse T3 (rT3) — Typical levels
  • Free T3 (fT3) — Typical levels
  • Insulin — Typical levels
  • Ghrelin — Typical levels
  • IGF-1 — Typical levels
  • Leptin — Typical levels
  • Adiponectin — Typical levels
  • Growth Hormone — Typical levels
  • Cortisol — Typical levels
  • Cushing’s Syndrome — Typical likelihood
  • Addison’s Disease — Typical likelihood
  • HPA Axis — Typical likelihood
  • TPO (Thyroid) — Typical
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • GIPR (Blood Sugar) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-18B423
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-18B423 · © 2026 Marrow Health.