Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 5 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Gut Health62 results reported of 65 analytes · 50 recommendations
Liver & Gallbladder Health25 results reported of 25 analytes · 50 recommendations
Food Sensitivities23 results reported of 23 analytes · 49 recommendations
Histamine12 results reported of 12 analytes · 16 recommendations
Gluten Sensitivity4 results reported of 4 analytes · 15 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 108 results here, 21 came back worth discussing with a clinician and 9 came back in your favour. Bring this document to your appointment.
What this package looks at
Gut Health — Your gut is an amazingly complex system of organs, finely tuned to take in and process nutrients and then get rid of the waste. Besides supplying you with the energy you need, it is also a central hub for overall health, comprising about 70% of your immune system and having a direct
Liver & Gallbladder Health — The liver is a vital organ that plays a central role in metabolism, detoxification, and overall bodily health. Genetic factors can significantly influence the liver's function and an individual's susceptibility to various liver conditions.
Histamine — Histamine is a crucial molecule that plays multiple roles in your body, from immune responses to neurotransmitter function and digestion. This analysis explores genetic variations that influence every aspect of histamine metabolism -from production and storage to breakdown and
Gluten Sensitivity — Why do some people react strongly to gluten while others can eat it without issue? The answer often lies in our genes, particularly in the HLA gene family. This report examines genetic factors that influence both celiac disease and non-celiac gluten sensitivity, mapping out how different
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Elimination DietBegin by removing foods you suspect might be causing adverse reactions for 2-3 weeks.
Relates to: Food Sensitivities, Food Allergies, Egg Allergy
2
Avoid Food TriggersIdentify foods that trigger negative reactions in your body, such as digestive issues, allergies, or headaches, and eliminate them from your diet entirely.
Relates to: Food Allergies, SH2B3 (Autoimmunity)
3
Gluten-Free DietCheck labels for gluten-free certification, and aim to maintain this diet consistently, as even small amounts of gluten can cause symptoms to recur in sensitive individuals.
Relates to: Gluten Sensitivity (Non-Celiac), SH2B3 (Autoimmunity)
4
Eat Fiber-Rich Foodsgrams per day, spread out over all meals.
Relates to: Colorectal Cancer, Hemorrhoids, Irritable Bowel (IBS), Crohn’s Disease
5
Dietary SphingolipidsAim to include foods like eggs, dairy products (such as cheese, yogurt, and milk), and soy-based foods in your meals regularly.
Relates to: Food Sensitivities, Food Allergies
6
Whole-Food Plant-Based Dietfew weeks to avoid digestive discomfort.
Relates to: Colorectal Cancer, Pancreas Inflammation, Acid Reflux, Gut Microbiome Diversity
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
ProbioticsRelates to: Diarrhea, Acid Reflux, C. difficile Infection, Flatulence (Gas)
2
ButyrateRelates to: Food Sensitivities, Food Allergies
3
Niacin SupplementsRelates to: Food Sensitivities, Food Allergies
4
Dietary Omega-3 Fatty AcidsRelates to: Food Sensitivities, Food Allergies, Excessive Mast Cells
5
Resistant StarchRelates to: Food Sensitivities, Food Allergies
6
TryptophanRelates to: Food Sensitivities, Food Allergies
7
Saccharomyces BoulardiiRelates to: Diarrhea, Bloating, Flatulence (Gas), Gut Microbiome Diversity
8
Vitamin CRelates to: Food Sensitivities, Food Allergies, Excessive Mast Cells
Your headline findings
Of the 108 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Peptic UlcersMore likely
More likely to have peptic ulcers based on 113,543 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: Up to 30% of differences in people's chances of developing peptic ulcers may be attributed to genetics.
Risk factors include: stress, mental health issues, smoking, alcohol use, excessive NSAID use, H.
If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.
What you can do
- Coffee
I M PAC T EVIDENCE Peptic Ulcers Experts suggest that many peptic ulcers are primarily caused by an infection with the bacterium Helicobacter pylori (H. pylori), rather than by consuming spicy foods or living a stressful lifestyle. - Avoid Carbonated Beverages
Stop consuming drinks like soda, sparkling water, and other carbonated beverages.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Gut Health report
Acid RefluxMore likely
More likely to have GERD based on 222,102 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: About 40% of differences in people's chances of developing GERD may be attributed to genetics.
It affects about 1 in 5 people in the U.S.
GERD affects about 1 in 5 people in the U.S.
What you can do
- Avoid Large Meals
Divide your daily food intake into smaller portions spread out over five to six times a day instead of having three large meals. - Whole-Food Plant-Based Diet
few weeks to avoid digestive discomfort.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Gut Health report
Gastrointestinal InfectionMore likely
More likely to get a GI infection based on 49,910 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Gastrointestinal (GI) infections are diseases of the digestive system.
They are caused by the invasion of microbes that do not usually live there.
The main sources of infection include: Person-to-person contact Consumption of contaminated food (e.g., undercooked or poorly stored meat, raw milk) Consumption of contaminated water (e.g., river or swimming pool water) Contact with contaminated objects (e.g., soil, work tools) Contact with animals or their feces (e.g., contact with farm animals and pets, visiting petting zoos) Risk factors for GI infections include [R, R, R, R, R, R].
Ask your clinician about
- Probiotics
- Zinc
- Lactobacillus Rhamnosus GG
Named only. Marrow gives no dose and does not recommend these.
From your Gut Health report
BloatingMore likely
More likely to bloat based on 1,662 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Factors that might increase the risk or cause bloating include: Consuming high-fat foods, which can delay stomach emptying.
Swallowing air while eating or drinking.
Gastrointestinal infections or imbalances in gut bacteria.
Ask your clinician about
- Saccharomyces Boulardii
- Lactobacillus Plantarum
- Lactobacillus Rhamnosus
Named only. Marrow gives no dose and does not recommend these.
From your Gut Health report
Rectal ProlapseMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.
What this actually is
Symptoms of rectal prolapse include a sensation of a bulging from the anus, discharge of mucus or blood, anal pain, fecal incontinence, or an obstructed bowel movement.
The causes are diverse, ranging from chronic constipation, straining during bowel movements, weakened pelvic floor muscles due to age, previous surgeries, or childbearing.
More likely to have Treatment hinges on the severity and can vary from self-care 10,706 genetic techniques and exercises to strengthen the pelvic floor, to surgical interventions aimed at repairing and securing the rectum in its proper place.
What you can do
- Eat Fiber-Rich Foods
grams per day, spread out over all meals.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Gut Health report
Non-Viral HepatitisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.
What you can do
- Coffee
I M PAC T EVIDENCE Peptic Ulcers Experts suggest that many peptic ulcers are primarily caused by an infection with the bacterium Helicobacter pylori (H. pylori), rather than by consuming spicy foods or living a stressful lifestyle.
Ask your clinician about
- Taurine
- Milk Thistle (Silymarin)
Named only. Marrow gives no dose and does not recommend these.
From your Liver & Gallbladder Health report
Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.
These mutations are usually acquired during a person's life rather than being inherited.
Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.
Ask your clinician about
- Quercetin
- Dietary Omega-3 Fatty Acids
- Vitamin C
Named only. Marrow gives no dose and does not recommend these.
From your Histamine report
Intestinal ObstructionMore likely
More likely to have an intestinal obstruction based ications may be given to reduce pain and on 854,609 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.
What this actually is
Intestinal Treatment for cause and the liquid diet and clear on its own.
However, more where intravenous dehydration, and vomiting.
What you can do
- Avoid Large Meals
Divide your daily food intake into smaller portions spread out over five to six times a day instead of having three large meals. - Avoid Carbonated Beverages
Stop consuming drinks like soda, sparkling water, and other carbonated beverages.
From your Gut Health report
A further 13 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Risk factors include being under age 30, European ancestry, and smoking.
IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.
IBD only affects about 3 in 1000 people worldwide.
From your Gut Health report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Other risk factors include being young and male.
is not rare, happening to about 7-8% of people in their lifetime.
If your genetic risk is high, know the symptoms and seek medical attention if you have them.
From your Gut Health report
Alcoholic LiverLess likely
Less likely to have alcoholic liver disease based on 1,664 genetic variants we looked at
Your risk is greater than 13% of the population and lower than 87% of the population.
What this actually is
As ALD advances, the liver's ability to function properly diminishes, leading to serious health issues including jaundice, coagulopathy, and the buildup of toxins in the bloodstream that can affect brain function—a condition known as hepatic encephalopathy.
In late stages, patients may develop life-threatening complications such as ascites, which is the accumulation of fluid in the abdomen, and variceal bleeding due to increased pressure in the portal vein.
Abstinence from alcohol is the most critical factor in treatment and prevention of disease progression, accompanied by dietary changes and, in severe cases, the consideration for liver transplantation.
From your Liver & Gallbladder Health report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (13)
- Pancreas Inflammation — More likely, 95th percentile
- Food Allergies — More likely, 95th percentile
- Irritable Bowel (IBS) — More likely, 94th percentile
- Peanut Allergy — More likely, 93th percentile
- Hemorrhoids — More likely, 90th percentile
- C. difficile Infection — More likely, 87th percentile
- Flatulence (Gas) — More likely, 84th percentile
- Shigella Infection — More likely, 84th percentile
- Diarrhea — More likely, 80th percentile
- Egg Allergy — More likely, 80th percentile
- Colorectal Cancer — More likely, 73th percentile
- Crohn’s Disease — More likely, 66th percentile
- Food Sensitivities — More likely
Running above the typical range (11)
- ALT — Higher levels, 88th percentile
- Gluten Sensitivity (Non-Celiac) — Higher
- Alcohol Sensitivity — Higher
- NLRP3 (Gut Inflammation) — Higher activity
- Albumin — Higher levels
- Dairy Sensitivity (Casein) — Higher
- HNMT (Histamine) — Higher activity
- Oxalate Sensitivity — Higher
- CYP1A2 (Detox) — Higher activity
- MAOB (Dopamine/ Norepinephrine) — Higher activity
- MAOA (Dopamine/Serotonin) — Higher activity
Running below the typical range (9)
- IBD5 (Gut Inflammation) — Lower activity, 19th percentile
- Caffeine Sensitivity — Lower
- Gut Microbiome Diversity — Lower
- HNF4A (Gut Inflammation) — Lower activity
- JAK2 (Gut Inflammation) — Lower activity
- Bilirubin — Lower levels
- ALDH2 (Alcohol Sensitivity) — Lower activity
- HRH1 (Allergies) — Lower activity
- SH2B3 (Autoimmunity) — Lower activity
Working in your favour (6)
- Malabsorption — Less likely, 14th percentile
- Diverticular Disease — Less likely
- HRH2 (Gut Health) — Better genetics
- KIAA1109 (Gut Inflammation) — Better genetics
- Liver Cirrhosis — Less likely
- Liver Failure — Less likely
In line with most people (58)
- Anal Fissure — Typical likelihood, 78th percentile
- Shrimp Allergy — Typical likelihood, 74th percentile
- H. pylori — Typical likelihood, 67th percentile
- Bowel Incontinence — Typical likelihood, 66th percentile
- Esophageal Varices — Typical likelihood, 66th percentile
- Gallstones — Typical likelihood, 66th percentile
- Ulcerative Colitis — Typical likelihood, 63th percentile
- Hiatus Hernia — Typical likelihood, 50th percentile
- Fatty Liver — Typical likelihood, 49th percentile
- EBV Infection — Typical likelihood, 48th percentile
- Colorectal Polyps — Typical likelihood, 44th percentile
- Stomach Inflammation — Typical likelihood, 42th percentile
- Celiac Disease — Typical likelihood, 42th percentile
- Bile Duct Inflammation — Typical likelihood, 39th percentile
- HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
- AST — Typical levels, 38th percentile
- Nausea — Typical likelihood, 36th percentile
- Milk Allergy — Typical likelihood, 36th percentile
- Reduced Bile Flow — Typical likelihood, 30th percentile
- Vomiting — Typical likelihood, 27th percentile
- Stomach Pain — Typical likelihood, 27th percentile
- Stomach Bug — Typical likelihood, 27th percentile
- Indigestion — Typical likelihood, 20th percentile
- Gallbladder Inflammation — Typical likelihood, 20th percentile
- Constipation — Typical likelihood, 16th percentile
- Stool Frequency — Typical
- Leaky Gut — Typical
- Esophageal Cancer — Typical likelihood
- Stomach Cancer — Typical likelihood
- Barrett's Esophagus — Typical likelihood
- Low Stomach Acid — Typical likelihood
- Salt Sensitivity — Typical
- Histamine Intolerance — Typical likelihood
- Lactose Intolerance — Likely tolerant
- Bifidobacterium — Typical levels
- Bifidobacterium Longum — Typical levels
- Bifidobacterium Breve — Typical levels
- Bifidobacterium Bifidum — Typical levels
- SLC22A4 (Gut Inflammation) — Typical genetics
- Liver Cancer — Typical likelihood
- Hepatitis B — Typical likelihood
- Hepatitis C — Typical likelihood
- Gallbladder Cancer — Typical likelihood
- Bile Duct Cancer — Typical likelihood
- Biliary Cirrhosis — Typical likelihood
- GGT — Typical levels
- Alkaline Phosphatase — Typical levels
- Choline — Typical need
- PEMT (Choline) — Typical activity
- CHDH (Choline) — Typical genetics
- ABCG8 (Cholesterol & Gallstones) — Typical activity
- HLA-DQ (Gluten) — Typical genetics
- DAO (Histamine) — Typical activity
- Chili Pepper Sensitivity — Typical
- SLC4A5 (Salt & Blood Pressure) — Typical genetics
- Salicylate Sensitivity — Typical
- IgE — Typical levels
- NAT2 (Detox) — Intermediate
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.