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Genomics · Genetic Reports · Precision Wellness

Hormone Health Package

Personalized 5-Report Genetic Package
Hormone HealthSex HormonesThyroid HealthPerimenopauseFertility & Reproductive Health
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-3D292E
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-3D292E
Reports in package
5
Results scored
94 of 133
Need attention
10
Report
Summary Report

The reports inside this package

This one document contains 5 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Hormone Health46 results reported of 46 analytes · 50 recommendations
Sex Hormones12 results reported of 12 analytes · 47 recommendations
Thyroid Health15 results reported of 15 analytes · 41 recommendations
Perimenopause27 results reported of 27 analytes · 50 recommendations
Fertility & Reproductive Health30 results reported of 33 analytes · 49 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 94 results here, 10 came back worth discussing with a clinician and 8 came back in your favour. Bring this document to your appointment.

What this package looks at

Hormone Health — Your hormonal (endocrine) system regulates body processes, such as appetite, sex drive, tissue repair, metabolism, and more. Hormones affect more or less everything in your body!

Sex Hormones — Sex hormones and reproductive hormones play vital roles in regulating physical development, reproductive function, and overall health. These hormones influence everything from muscle mass and bone density to fertility, libido, and mood. Genetic predispositions can affect how these

Thyroid Health — The thyroid gland plays a vital role in regulating metabolism, energy levels, and overall hormonal balance. Thyroid health can significantly impact various bodily functions, from weight management and energy production to mood and cardiovascular health.

Perimenopause — Genetic factors significantly influence how women experience the menopausal transition, affecting both symptom severity and health risks. This comprehensive report examines genetic variants associated with common perimenopausal symptoms, increased health risks during this

Fertility & Reproductive Health — Female reproductive health is influenced by a complex interaction of genetics, hormones, and environmental factors. Genetics plays a significant role in determining a woman's predisposition to fertility issues, menstrual cycle irregularities, and reproductive hormone imbalances.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Interpersonal Therapy50 minutes

Engage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.

Relates to: Low Mood
relevance
2
Psychodynamic Therapy

Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.

Relates to: Low Mood
relevance
3
Sunlight Exposure20 minutes

Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.

Relates to: Low Mood
relevance
4
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Low Mood, Menopause Symptoms
relevance
5
Probiotics
Relates to: Low Mood
relevance
6
Cherries

Incorporate a serving of cherries, which is about 1 cup or 21 cherries, into your daily diet.

Relates to: Low Mood, Irritability
relevance
7
Morning Bright Light Therapy20 minutes

Expose yourself to a light therapy box, which mimics natural sunlight, for about 20-30 minutes each morning TA within the first hour of waking up.

Relates to: Low Mood
relevance
8
Progressive Muscle Relaxation10 minutes

TA the muscles in your feet for 5 seconds, then relax for 30 seconds, and progressively work your way up through the major muscle groups of your body, tensing then relaxing each for 5 and 30 seconds respectively.

Relates to: Low Mood, Menopause Symptoms
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
DHEA (Dehydroepiandrosterone)
Relates to: DHEAS
relevance
2
St. John's Wort
Relates to: Low Mood, Menopause Symptoms
relevance
3
Tryptophan
Relates to: Low Mood, Menopause Symptoms
relevance
4
Resistant Starch
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1, Low Mood
relevance
5
Berberine
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
6
Maintain Optimal Vitamin D Levels
Relates to: Thyroid Inflammation
relevance

Your headline findings

Of the 94 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Menopause SymptomsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.

What this actually is

Genetics plays a role in the age at which menopause starts and the severity of symptoms.

For example, genetic variations that influence the metabolism of sex hormones are associated with the frequency and severity of hot flashes.

Women often follow a similar pattern as their mothers or sisters.

What you can do

  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Ask your clinician about

  • St. John's Wort
  • Black Cohosh

Named only. Marrow gives no dose and does not recommend these.

From your Perimenopause report
MiscarriageMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The causes of is chromosomal pregnancy Hormonal to sustain the Immune system because the unwanted Uterine problems with from developing Infections: miscarriage.

Lifestyle and extreme to the risk.

Underlying diabetes, increase the Diagnosing a ultrasound, and levels.

What you can do

  • Avoid Formaldehyde Exposure
    Aim to reduce use of pressed wood products and seek out alternatives when possible.
  • Avoid Phthalate Exposure
    Avoid Phthalate To avoid phthalate exposure, check product labels and choose phthalate-free options for personal care items, plastics (look for recycling codes 3 and 7 or the letters 'V' or 'PVC'), and household products.
  • Avoid Mycotoxin
    Avoid Noise Pollution Minimize exposure to loud environments by using noise-cancelling headphones or earplugs, especially in areas known for high noise levels such as construction sites, concerts, and busy urban streets.
From your Fertility & Reproductive Health report
Abnormal Vaginal BleedingMore likely
More likely to have abnormal vaginal bleeding based on 66,937 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

The assessment of abnormal vaginal bleeding typically involves a detailed personal medical history and a physical examination, including pelvic examination.

Further diagnostic procedures might include ultrasounds, blood tests to check hormone levels, and sometimes a biopsy to rule out endometrial pathology.

Treatment options vary based on the cause and may include hormonal therapies, such as birth control pills or intrauterine devices (IUDs), medications to control bleeding, or surgical treatments.

What you can do

  • Avoid Douching
    Avoid Exposure To Organic Solvents Ensure to work in well-ventilated areas and wear protective gear when handling products like paints, varnishes, and adhesives.

Ask your clinician about

  • Black Cohosh

Named only. Marrow gives no dose and does not recommend these.

From your Fertility & Reproductive Health report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Limit Soy Intake Reduce your consumption of soy and soy-based products to no more than 1-2 servings per week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Selenium Supplements

Named only. Marrow gives no dose and does not recommend these.

From your Thyroid Health report
Heavy SweatingMore likely
More likely to have hyperhidrosis based on 104 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.

What this actually is

Key Takeaways: Genes that affect excessive sweating may influence nerve function and chemical messengers.

Excessive sweating can impact quality of life and cause undue stress and anxiety.

If you have symptoms, you may want to consult your doctor to rule out other conditions.

What you can do

  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.
  • Limit Manganese Exposure
    Avoid consuming water with high levels of manganese by using filters certified to remove it, especially if your water comes from a well.
  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.
From your Perimenopause report
Sexual DysfunctionMore likely
More likely to have sexual dysfunction based on 1,671 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

Key Takeaways: About 40% of differences in people's chances of developing sexual dysfunction may be due to genetics.

Risk factors include getting older, hormone changes, stress, and certain health conditions.

If you are experiencing symptoms, check with your doctor for possible solutions.

What you can do

  • Sleep for 7+ Hours
    Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.

Ask your clinician about

  • Methylfolate
  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Perimenopause report
Low MoodMore likely
More likely to have chronically low mood based on 84,205 genetic variants we looked at
Your risk is greater than 85% of the population and lower than 15% of the population.

What this actually is

Key Takeaways: About 40% of differences in people's odds of developing depression may be due to genetics.

It is more likely for young adults and the elderly but can affect people of all ages.

Other risk factors include traumatic and stressful events, serious medical conditions, and substance use problems.

What you can do

  • Interpersonal Therapy 50 minutes
    Engage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.
  • Psychodynamic Therapy
    Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
  • Sunlight Exposure 20 minutes
    Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.
From your Perimenopause report
Female InfertilityMore likely
More likely to have fertility problems based on 569 genetic variants we looked at
Your risk is greater than 85% of the population and lower than 15% of the population.

What this actually is

Key Takeaways: Genes affecting fertility may impact puberty and menopause.

Even without heritability numbers, managing risk factors like diet and not smoking, can help mitigate your overall risk.

Risk factors include age, smoking, over/underweight, past sexually transmitted infections, alcohol use, and PCOS.

What you can do

  • Avoid PAHs Exposure
    Use exhaust fans in kitchens and ensure proper ventilation when cooking at high temperatures to reduce indoor levels of PAHs.
  • Avoid Formaldehyde Exposure
    Aim to reduce use of pressed wood products and seek out alternatives when possible.

Ask your clinician about

  • Black Cohosh

Named only. Marrow gives no dose and does not recommend these.

From your Fertility & Reproductive Health report
A further 2 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.

About 60-70% of the differences in people’s cognitive decline may come from genetics.

For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].

From your Perimenopause report
OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.

Weight gain affects conditions like high blood sugar and heart disease.

However, it is highly modifiable by diet and exercise.

From your Perimenopause report
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Perimenopause report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (2)
  • Uterine Fibroids — More likely, 82th percentile
  • TCF7L2 (Blood Sugar/Diet) — Worse genetics
Running above the typical range  (12)
  • Irritability — Higher, 95th percentile
  • FSH — Higher levels
  • SHBG — Higher levels
  • Estradiol (M) — Higher levels
  • Testosterone — Higher levels
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • DIO1 (Thyroid) — Higher activity
  • DIO2 (Thyroid) — Higher activity
  • GHR — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
  • Testosterone (F) — Higher levels
  • Estradiol — Higher levels
Running below the typical range  (8)
  • DHEAS — Lower levels
  • Luteinizing Hormone (LH) — Lower levels
  • Pregnenolone — Lower levels
  • Prolactin — Lower levels
  • GLP-1 — Lower levels
  • CRHR2 (Stress/HPA Axis) — Lower activity
  • CRHR1 (Stress/HPA Axis) — Lower activity
  • FKBP5 (Stress/ HPA Axis) — Lower activity
Working in your favour  (5)
  • Heavy Periods — Less likely, 17th percentile
  • Preterm Labor — Less likely, 14th percentile
  • Ovarian Cysts — Less likely, 3th percentile
  • Preeclampsia — Less likely
  • Gestational Diabetes — Less likely
In line with most people  (56)
  • Stillbirth — Typical likelihood, 74th percentile
  • Vaginal Atrophy — Typical likelihood, 67th percentile
  • Pelvic Inflammatory Disease — Typical likelihood, 66th percentile
  • Total Cholesterol — Typical levels, 61th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Ectopic Pregnancy — Typical likelihood, 59th percentile
  • Anxiety — Typical likelihood, 57th percentile
  • Type 2 Diabetes — Typical likelihood, 49th percentile
  • Hashimoto's Disease — Typical likelihood, 47th percentile
  • PCOS — Typical likelihood, 47th percentile
  • Overactive Thyroid — Typical likelihood, 46th percentile
  • Endometriosis — Typical likelihood, 46th percentile
  • LDL Cholesterol — Typical levels, 44th percentile
  • Irregular Periods — Typical likelihood, 36th percentile
  • Underactive Thyroid — Typical likelihood, 34th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Triglycerides — Typical levels, 16th percentile
  • Free T4 — Typical levels
  • T3 (Triiodothyronine) — Typical levels
  • T4 (Thyroxine) — Typical levels
  • TSH — Typical levels
  • Graves' Disease — Typical likelihood
  • Reverse T3 (rT3) — Typical levels
  • Free T3 (fT3) — Typical levels
  • Bioavailable Testosterone — Typical levels
  • DHT — Typical levels
  • Progesterone — Typical levels
  • Insulin — Typical levels
  • Ghrelin — Typical levels
  • IGF-1 — Typical levels
  • Leptin — Typical levels
  • Adiponectin — Typical levels
  • Growth Hormone — Typical levels
  • Cortisol — Typical levels
  • Cushing’s Syndrome — Typical likelihood
  • Addison’s Disease — Typical likelihood
  • HPA Axis — Typical likelihood
  • TPO (Thyroid) — Typical
  • ESR1 (Estrogen) — Typical activity
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • GIPR (Blood Sugar) — Typical activity
  • Thyroid Cancer — Typical likelihood
  • Sleep Quality — Typical
  • Vitamin D — Typical need
  • HDL Cholesterol — Typical levels
  • Fasting Glucose — Typical levels
  • Red Blood Cells — Typical levels
  • Iron — Typical need
  • Pelvic Organ Prolapse — Typical likelihood
  • Ovarian Cancer — Typical likelihood
  • Endometrial Cancer — Typical likelihood
  • Cervical Cancer — Typical likelihood
  • Hyperemesis Gravidarum — Typical likelihood
  • Postpartum Depression — Typical likelihood
  • Bioavailable Testosterone (F) — Typical levels

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-3D292E
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-3D292E · © 2026 Marrow Health.