Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Inflammation & Autoimmunity80 results reported of 83 analytes · 50 recommendations
Immunity & Infections77 results reported of 77 analytes · 50 recommendations
HLA DNA Autoimmunity7 results reported of 7 analytes · 12 recommendations
Histamine12 results reported of 12 analytes · 16 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 151 results here, 23 came back worth discussing with a clinician and 12 came back in your favour. Bring this document to your appointment.
What this package looks at
Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.
Immunity & Infections — The immune system is the body’s primary defense against infections, working tirelessly to ward off harmful viruses, bacteria, and other pathogens. However, genetic factors can influence how effectively your immune system responds to various infections and how prone you may be
HLA DNA Autoimmunity — Your immune system's ability to distinguish between "self" and "non-self" is largely influenced by your HLA (Human Leukocyte Antigen) genes. These genes act like your body's security system, playing a crucial role in how your immune system recognizes and responds to various threats.
Histamine — Histamine is a crucial molecule that plays multiple roles in your body, from immune responses to neurotransmitter function and digestion. This analysis explores genetic variations that influence every aspect of histamine metabolism -from production and storage to breakdown and
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Safer Sex PracticesReduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners.
Relates to: Genital Herpes, Flu
2
ProbioticsRelates to: C. difficile Infection, Gastrointestinal Infection, Yeast Infection, Flu
3
Regular Hand WashingDo this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
Relates to: Flu, C. difficile Infection, Gastrointestinal Infection, Eye Stye
4
Whole-Food Plant-Based Dietfew weeks to avoid digestive discomfort.
Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
5
Drink at Least 8 Glasses of Water a DayConsume a total of at least (or approximately 1.9 liters) of water over the course of the day.
Relates to: C. difficile Infection, Gastrointestinal Infection, Urinary Tract Infections, Acute Bronchitis
6
Good Hygiene PracticesWash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home.
Relates to: Flu, C. difficile Infection
7
Airway Muscle Training30 minutesPerform airway muscle training exercises daily for at least 30 minutes.
Relates to: Long COVID
8
Exercise TherapyBegin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.
Relates to: Long COVID
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
ZincRelates to: Gastrointestinal Infection, C. difficile Infection, Flu, Shigella Infection
2
Good Oral HygieneRelates to: Yeast Infection, Flu, Gastrointestinal Infection, Pneumococcal Disease
3
PrebioticsRelates to: Gut Microbiome Diversity, C. difficile Infection
4
Maintain Optimal Vitamin D LevelsRelates to: Crohn’s Disease, Thyroid Inflammation, Urinary Tract Infections, HLA-DOB (Inflammation)
5
Omega-3 (Fish Oil)Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
6
Dietary Omega-3 Fatty AcidsRelates to: Crohn’s Disease, Myocarditis, Nephritis, Pancreas Inflammation
Your headline findings
Of the 151 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.
Ask your clinician about
- Maintain Optimal Vitamin D Levels
- Zinc
- Good Oral Hygiene
Named only. Marrow gives no dose and does not recommend these.
From your Inflammation & Autoimmunity report & Immunity & Infections
FluMore likely
More likely to get the flu based on 8,860 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Flu (influenza) is a respiratory infection of the nose, throat and lungs, transferred via droplets that are either inhaled or picked up from surfaces.
Studies show that genetic factors can play a significant role in the risk of developing severe flu symptoms.
What you can do
- Regular Hand Washing
Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage. - Good Hygiene Practices
Wash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home. - Probiotics
From your Immunity & Infections report
Yeast InfectionMore likely
More likely to have yeast infections based on 104,352 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Candida albicans is a fungus that normally lives in and on the body.
If its environment changes and promotes its growth, Candida can multiply and lead to an infection.
This is called a yeast infection or candidiasis.
What you can do
- Probiotics
- Topical Aloe Vera
Avoid using scented products like douches, sprays, or powders in the genital area.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Immunity & Infections report
Gastrointestinal InfectionMore likely
More likely to get a GI infection based on 49,910 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Gastrointestinal (GI) infections are diseases of the digestive system.
They are caused by the invasion of microbes that do not usually live there.
The main sources of infection include: Person-to-person contact Consumption of contaminated food (e.g., undercooked or poorly stored meat, raw milk) Consumption of contaminated water (e.g., river or swimming pool water) Contact with contaminated objects (e.g., soil, work tools) Contact with animals or their feces (e.g., contact with farm animals and pets, visiting petting zoos) Risk factors for GI infections include [R, R, R, R, R, R].
What you can do
- Probiotics
- Regular Hand Washing
Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Immunity & Infections report
Eye StyeMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population ng treatments can help alleviate symptoms and lower than 1% of the population.
What this actually is
Styes can develop eyelashes become factors include: Poor hygiene: transfer Makeup use: remove makeup blockages.
Eye irritation: hygiene or Chronic are more prone Most styes heal on However, the and speed up Warm affected eyelid help the stye Massage: Gently may help applying warm Keep it clean: keeping it Avoid makeup makeup or further relievers can Preventive measures removing makeup the eyes with significantly eye infections.
What you can do
- Regular Hand Washing
Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
From your Immunity & Infections report
Genital HerpesMore likely
More likely to get genital herpes based on 284,981 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Genital herpes is a common sexually transmitted infection (STI), usually caused by the herpes simplex virus type 2 (HSV-2).
Genetics may also affect susceptibility to genital herpes.
Involved genes may play a role in the immune response, cell life cycle, and more.
What you can do
- Safer Sex Practices
Reduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners. - Topical Aloe Vera
Avoid using scented products like douches, sprays, or powders in the genital area.
From your Immunity & Infections report
Low NeutrophilsMore likely
More likely to have neutropenia based on 1,674 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Neutropenia is typically diagnosed through a complete blood count test, which evaluates the levels of various types of cells in the blood.
If neutropenia is detected, further tests may be required to determine its cause: Bone marrow biopsy: To examine the health and status of the bone marrow.
Blood tests: To check for infections, vitamin deficiencies (such as B12 and folate), and autoimmune disorders.
What you can do
- Avoid Crowds
Minimize your time in crowded places by scheduling your errands during off-peak hours, avoiding public events known to draw large crowds, and choosing less crowded routes or modes of transportation.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Immunity & Infections report
Urinary Tract InfectionsMore likely
More likely to have UTIs based on 37,658 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Key Takeaways: About 150 million people get at least one UTI per year.
They're much more common in women.
Women at a high genetic risk may want to take precautions, such as staying hydrated and maintaining personal hygiene.
What you can do
- Drink at Least 8 Glasses of Water a Day
Consume a total of at least (or approximately 1.9 liters) of water over the course of the day. - Probiotics
Ask your clinician about
- Maintain Optimal Vitamin D Levels
Named only. Marrow gives no dose and does not recommend these.
From your Immunity & Infections report
A further 15 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Athlete’s FootLess likely
Lower predisposition than 98% of people
Your result sits lower than 98% of the population.
What this actually is
Symptoms of athlete's foot include itching, stinging, and burning sensations between the toes or on soles of the feet.
The skin may also flake, peel, and crack, sometimes leading to pain, swelling, and blisters.
A distinctive sign is a scaly, red rash that itches intensely, often accompanied by a foul odor.
From your Immunity & Infections report
Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Risk factors include being under age 30, European ancestry, and smoking.
IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.
IBD only affects about 3 in 1000 people worldwide.
From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Other risk factors include being young and male.
is not rare, happening to about 7-8% of people in their lifetime.
If your genetic risk is high, know the symptoms and seek medical attention if you have them.
From your Inflammation & Autoimmunity report & Immunity & Infections
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (15)
- Excessive Mast Cells — More likely, 97th percentile
- Thyroid Inflammation — More likely, 96th percentile
- Pancreas Inflammation — More likely, 95th percentile
- Swollen Lymph Nodes — More likely, 94th percentile
- Acute Bronchitis — More likely, 90th percentile
- Urethra Inflammation — More likely, 88th percentile
- C. difficile Infection — More likely, 87th percentile
- Eye Inflammation — More likely, 84th percentile
- Shigella Infection — More likely, 84th percentile
- Crohn’s Disease — More likely, 66th percentile
- Psoriasis — More likely, 65th percentile
- Myocarditis — More likely
- Nephritis — More likely
- Long COVID — More likely
- Pneumococcal Disease — More likely
Running above the typical range (13)
- HLA (Inflammation) — Higher activity, 80th percentile
- Basophils — Higher levels
- HLA-DOB (Inflammation) — Higher activity
- NF-kB (Inflammation) — Higher activity
- NLRP3 (Gut Inflammation) — Higher activity
- ANKRD55 (Autoimmune) — Higher activity
- ABCB1 (Chronic Lyme) — Higher activity
- HNMT (Histamine) — Higher activity
- IgA — Higher levels
- IL-23R (Th17) — Higher levels
- GPX1 (Glutathione/Detox) — Higher activity
- MAOB (Dopamine/ Norepinephrine) — Higher activity
- MAOA (Dopamine/Serotonin) — Higher activity
Running below the typical range (13)
- SH2B3 (Autoimmunity) — Lower activity
- HNF4A (Gut Inflammation) — Lower activity
- CTLA4 (Autoimmunity) — Lower activity
- IL1B (Inflammation/ Fatigue) — Lower activity
- JAK2 (Gut Inflammation) — Lower activity
- IL8 (Inflammation) — Lower activity
- IL21 (Autoimmunity & Allergies) — Lower activity
- Gut Microbiome Diversity — Lower
- UGT2A1 (Cognition) — Lower activity
- GCLC (Glutathione & Detox) — Lower activity
- GSTA1 (Detox/ Glutathione) — Lower activity
- HRH1 (Allergies) — Lower activity
- ALDH2 (Alcohol Sensitivity) — Lower activity
Working in your favour (9)
- Optic Nerve Inflammation — Less likely, 19th percentile
- Ear Infection — Less likely, 19th percentile
- Common Cold — Less likely, 9th percentile
- Parasites — Less likely, 9th percentile
- Staph Infection — Less likely, 8th percentile
- Diverticular Disease — Less likely
- Sjogren's Syndrome — Less likely
- IL6R (Weight) — Better genetics
- HRH2 (Gut Health) — Better genetics
In line with most people (90)
- Respiratory Infections — Typical likelihood, 78th percentile
- Sore Throat — Typical likelihood, 77th percentile
- Mumps — Typical likelihood, 74th percentile
- Inner Ear Infection — Typical likelihood, 72th percentile
- Spleen Problems — Typical likelihood, 68th percentile
- H. pylori — Typical likelihood, 67th percentile
- Shingles — Typical likelihood, 65th percentile
- Bone Infection — Typical likelihood, 65th percentile
- Low White Blood Cells — Typical likelihood, 65th percentile
- Ulcerative Colitis — Typical likelihood, 63th percentile
- Chlamydia — Typical likelihood, 62th percentile
- Multiple Sclerosis — Typical likelihood, 60th percentile
- EBV Infection — Typical likelihood, 48th percentile
- Pneumonia — Typical likelihood, 46th percentile
- Warts — Typical likelihood, 46th percentile
- HPV Infection — Typical likelihood, 46th percentile
- Stomach Inflammation — Typical likelihood, 42th percentile
- Celiac Disease — Typical likelihood, 42th percentile
- Rheumatoid Arthritis — Typical likelihood, 40th percentile
- HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
- Inflammation (CRP) — Typical levels, 36th percentile
- Pink Eye — Typical likelihood, 33th percentile
- Ringworm — Typical likelihood, 32th percentile
- Impetigo (School Sores) — Typical likelihood, 30th percentile
- Eczema — Typical likelihood, 29th percentile
- Stomach Bug — Typical likelihood, 27th percentile
- Leg Cellulitis — Typical likelihood, 23th percentile
- IL-6 — Typical levels, 20th percentile
- Strep Infection — Typical likelihood, 20th percentile
- Type 1 Diabetes — Typical likelihood, 15th percentile
- Lupus — Typical likelihood, 12th percentile
- Chronic Lyme — Typical likelihood
- Sepsis — Typical likelihood
- Pulmonary Fibrosis — Typical likelihood
- Actinic Keratosis — Typical likelihood
- Meningitis — Typical likelihood
- Sarcoidosis — Typical likelihood
- Rheumatic Fever — Typical likelihood
- Psoriatic Arthritis — Typical likelihood
- Ankylosing Spondylitis — Typical likelihood
- Vitiligo — Typical likelihood
- Alopecia Areata — Typical likelihood
- Systemic Sclerosis — Typical likelihood
- Pemphigus Vulgaris — Typical likelihood
- Behcet’s Disease — Typical likelihood
- IgA Nephropathy — Typical likelihood
- TNF — Typical levels
- White Blood Cells — Typical levels
- Eosinophils — Typical levels
- Monocytes — Typical levels
- Neutrophils — Typical levels
- Erythrocyte Sedimentation Rate — Typical levels
- IgE — Typical levels
- IL-10 — Typical levels
- IL-17 (Th17) — Typical levels
- HLA-B (Autoimmune) — Typical
- HLA-DQ (Inflammation) — Typical activity
- HLA-DRB1 (Autoimmunity) — Typical
- HLA-DQA2 (Inflammation) — Typical
- TLR4 (Inflammation) — Typical activity
- PTPN22 (Autoimmunity) — Typical
- DAO (Histamine) — Typical activity
- STAT3 (Th1/Th17) — Typical activity
- TNF Gene (Inflammation) — Typical activity
- IL13 (Allergies, Lung Function) — Typical activity
- IL4 (Allergies, Autoimmunity) — Typical activity
- CRP Gene — Typical activity
- PADI4 (Autoimmune) — Typical activity
- IL10 Gene (Autoimmunity) — Typical activity
- SLC22A4 (Gut Inflammation) — Typical genetics
- Tuberculosis — Typical likelihood
- Whooping Cough (Pertussis) — Typical likelihood
- HIV/AIDS — Typical likelihood
- Malaria — Typical likelihood
- Scarlet Fever — Typical likelihood
- Gangrene — Typical likelihood
- Symptomatic HTLV-1 Infection — Typical likelihood
- Bifidobacterium — Typical levels
- Bifidobacterium Longum — Typical levels
- Bifidobacterium Breve — Typical levels
- Bifidobacterium Bifidum — Typical levels
- Glutathione — Typical function
- VDR (Vitamin D) — Typical activity
- IL6 Gene (Inflammation) — Typical activity
- MUC1 (Immunity, Gut, Minerals) — Typical genetics
- GPX4 (Selenium & Glutathione) — Typical activity
- GATA3 (Allergies) — Typical activity
- HLA-DQ (Gluten) — Typical genetics
- Histamine Intolerance — Typical likelihood
- NAT2 (Detox) — Intermediate
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.