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Genomics · Genetic Reports · Precision Wellness

Joint & Tendon Health Package

Personalized 4-Report Genetic Package
Joint & Tendon HealthBone HealthInjuriesPain
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-9E9326
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-9E9326
Reports in package
4
Results scored
89 of 98
Need attention
33
Report
Summary Report

The reports inside this package

This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Joint & Tendon Health27 results reported of 27 analytes · 50 recommendations
Bone Health17 results reported of 17 analytes · 50 recommendations
Injuries21 results reported of 21 analytes · 50 recommendations
Pain33 results reported of 33 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 89 results here, 33 came back worth discussing with a clinician and 8 came back in your favour. Bring this document to your appointment.

What this package looks at

Joint & Tendon Health — Joint and tendon health is essential for maintaining mobility, flexibility, and overall physical function. Genetic factors play a significant role in determining your susceptibility to various conditions that affect the joints and tendons, such as joint pain, arthritis, and tendon problems. While

Bone Health — Bone health is crucial for maintaining a strong skeletal system, mobility, and overall physical well-being. While lifestyle factors such as diet and exercise play important roles in bone health, genetics also significantly influences how strong and resilient your bones are.

Injuries — Injuries can significantly affect mobility, daily function, and quality of life. While accidents and physical activities are common causes of injury, genetics also plays a critical role in determining an individual’s susceptibility to certain types of injuries. Whether it's joint and tendon

Pain — We all experience pain from time to time, from stubbing a toe to hurting our knee or having a migraine attack. What makes us all different is the amount of pain we experience and how we handle it. There are lots of reasons for that, one of which is your DNA!

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Manual Therapy

Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), ACL Injury, Ankle Injury
relevance
2
Avoid Food Triggers

Try to limit caffeine to per day to avoid migraines.

Relates to: Migraines
relevance
3
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), ACL Injury, Ankle Injury
relevance
4
Shock Wave Therapy

Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.

Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement, Trigger Finger
relevance
5
Cognitive-Behavioral Therapy (CBT)

Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Relates to: Migraines, Chronic Pain, Fibromyalgia, Shoulder & Neck Pain
relevance
6
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, Long COVID, Jaw Disorders (TMJ), ACL Injury
relevance
7
Biofeedback

Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.

Relates to: Diabetic Neuropathy, Chronic Pain, Migraines, Shoulder & Neck Pain
relevance
8
Reduce Jaw Strain

Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.

Relates to: Jaw Disorders (TMJ)
relevance
9
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Chronic Pain, Migraines, Long COVID, Shoulder & Neck Pain
relevance
10
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Chronic Pain, Shoulder & Neck Pain
relevance
11
Core-Strengthening Exercises20 minutes

Aim to do TA these exercises for 20-30 minutes, 3 times a week.

Relates to: Low Back Injury, ACL Injury, Fibromyalgia, Abdominal Hernia
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Calcium, Hypoparathyroidism, Chronic Pain, Fibromyalgia
relevance
2
Magnesium
Relates to: Migraines, Chronic Pain, Cluster Headaches, Fibromyalgia
relevance
3
Dietary Calcium
Relates to: Hypoparathyroidism
relevance

Your headline findings

Of the 89 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Heel Pain (Plantar Fasciitis)More likely
More likely to have plantar fasciitis based on 28,598 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Factors that might increase the risk of developing plantar fasciitis include: Age, with it being most common between the ages of 40 and 60 Certain types of exercise, such as long-distance running or ballet dancing Foot mechanics, including having a high arch, flat feet, or an abnormal walking pattern Obesity, which places extra stress on the plantar fascia Occupations that require long periods of standing or walking on hard surfaces Wearing shoes with inadequate support Genetics While plantar fasciitis is primarily associated with environmental factors and physical stress on the foot, there is some evidence to suggest that genetic factors might play a role in predisposing certain individuals to the condition.

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
From your Joint & Tendon Health report
Groin HerniaMore likely
More likely to get a groin hernia based on 857,808 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

A hernia occurs when tissue from one body cavity bulges through an opening in your muscle wall into another.

Groin (inguinal) hernia is the most common type of hernia.

Others might occur as a result of: Increased pressure within the abdomen A preexisting weak spot in the abdominal wall Straining during bowel movements or urination Strenuous activity Pregnancy Chronic coughing or sneezing Genetics can have an impact on your susceptibility to a groin hernia.

From your Injuries report
Abdominal HerniaMore likely
More likely to have an abdominal hernia based on 11,533 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The following factors increase the risk of an abdominal hernia: Increased pressure in the abdomen: This can be due to heavy lifting, diarrhea, constipation, or persistent coughing or sneezing.

Weakness in the abdominal wall: This may be present at birth or develop later in life, often exacerbated by factors like age, chronic strain, or surgical incisions.

Pregnancy: It can put extra pressure on the abdomen.

What you can do

  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
From your Injuries report
MigrainesMore likely
More likely to have migraines based on 109,603 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: obesity, depression, stress, being female, blood vessel issues, brain chemical imbalances.

If you have a high genetic risk, take action on modifiable risk factors to help reduce overall risk.

About 16% of Americans regularly have migraines.

What you can do

  • Avoid Food Triggers
    Try to limit caffeine to per day to avoid migraines.
  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Neck ArthritisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.

What this actually is

As the disks in the cervical spine dehydrate and shrink, signs of osteoarthritis develop, including the formation of bony projections along the edges of bones (bone spurs).

Cervical spondylosis can sometimes lead to a narrowing of the space needed by the spinal cord and the nerve roots that pass through the spine to the rest of the body.

More likely to have When these nerve pathways are affected, individuals might 481,932 genetic experience neurological symptoms such as numbness, weakness, or tingling in the arms, hands, legs, or feet.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Femoral HerniaMore likely
More likely to have a femoral hernia based on 14,508 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

The symptoms of a femoral hernia can vary depending on its size and whether it becomes strangulated or not.

Patients may notice a small lump in the groin or upper thigh area that could be accompanied by discomfort or sharp pain, especially when straining or lifting heavy objects.

Strangulation, where the blood supply to the herniated tissue gets cut off, is a serious complication and can lead to nausea, vomiting, and severe pain and requires immediate medical attention to prevent further health risks.

From your Injuries report
Facial PainMore likely
Higher predisposition than 98% of people
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Diagnosing facial approach that can otolaryngologists, comprehensively and strategies could blocks, or surgery, For instance, sudden, severe resulting from Psychological also play pivotal the need for a plan.

What you can do

  • Biofeedback
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Low Back InjuryMore likely
More likely to have a low back injury based on 171,685 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Other risk factors include occupations involving repetitive motions or heavy lifting, prolonged sitting/standing, over 40, obesity, smoking, lack of physical activity, previous injury, and certain health conditions.

Lower back injuries are common among athletes, and account for 20% of workplace injuries.

If your genetic risk is high, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
  • Kinesio Taping
    Apply kinesio tape directly to the skin over the affected muscle or joint area.
From your Injuries report
A further 25 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Joint & Tendon Health report & Pain
Bone SpursLess likely
Less likely to have bone spurs based on 1,676 genetic variants we looked at
Your risk is greater than 5% of the population and lower than 95% of the population.

What this actually is

Bone spurs develop as a result of bone and joint degeneration and are primarily associated with the aging process.

However, they can also arise from underlying diseases and conditions that affect bone and joint health: Osteoarthritis: The most common cause of bone spurs, osteoarthritis involves the breakdown of cartilage, leading to joint damage and increased bone friction.

Spinal degeneration: Bone spurs commonly occur in the spine as a result of the degeneration of discs and joints, often due to aging.

From your Bone Health report
Tennis ElbowLess likely
Lower predisposition than 92% of people
Your risk is greater than 8% of the population s, and sometimes even surgery for severe and lower than 92% of the population.

What this actually is

Several factors elbow: Age: It's most Occupation: and arm, such this condition.

Certain sports: risk of tennis technique.

Genetics: Some that makes repetitive Managing tennis relieving cases.

From your Injuries report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (25)
  • Concussion — More likely, 96th percentile
  • Ear Pain — More likely, 94th percentile
  • ACL Injury — More likely, 92th percentile
  • Ankle Injury — More likely, 91th percentile
  • Shoulder Impingement — More likely, 90th percentile
  • Disc Degeneration — More likely, 90th percentile
  • Statin-Induced Muscle Pain — More likely, 90th percentile
  • Painful Urination — More likely, 88th percentile
  • Trigger Finger — More likely, 87th percentile
  • Herniated Disk — More likely, 87th percentile
  • Shoulder & Neck Pain — More likely, 84th percentile
  • Cluster Headaches — More likely, 82th percentile
  • Jaw Disorders (TMJ) — More likely, 81th percentile
  • Dupuytren’s Contracture — More likely, 80th percentile
  • Pressure Ulcers — More likely, 80th percentile
  • Chronic Pain — More likely, 80th percentile
  • Spinal Arthritis — More likely
  • Bone Cancer — More likely
  • Hypoparathyroidism — More likely
  • Calcium — Increased need
  • Vitamin K — Increased need
  • Painful Bladder Syndrome — More likely
  • Fibromyalgia — More likely
  • Diabetic Neuropathy — More likely
  • Long COVID — More likely
Running above the typical range  (3)
  • MMP1 (Collagen) — Higher activity
  • GC (Vitamin D) — Higher activity
  • TRPM8 (Pain) — Higher activity
Running below the typical range  (2)
  • TRPV1 (Pain) — Lower activity, 15th percentile
  • OPRM1 (Endorphins) — Lower activity
Working in your favour  (5)
  • Tendon Inflammation — Less likely, 19th percentile
  • Scoliosis — Less likely, 19th percentile
  • Tendon Injury — Less likely, 18th percentile
  • Ehlers-Danlos Syndrome (Progeroid — Less likely
  • ADAMTS5 (Joint Health) — Better genetics
In line with most people  (43)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Falls — Typical likelihood, 76th percentile
  • Back Pain — Typical likelihood, 76th percentile
  • Painful Intercourse — Typical likelihood, 74th percentile
  • Trigeminal Nerve Pain — Typical likelihood, 68th percentile
  • Muscle Pain — Typical likelihood, 68th percentile
  • Hip Fractures — Typical likelihood, 66th percentile
  • Bone Infection — Typical likelihood, 65th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Tension Headaches — Typical likelihood, 64th percentile
  • Spinal Canal Narrowing — Typical likelihood, 60th percentile
  • Gout — Typical likelihood, 58th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Headache — Typical likelihood, 51th percentile
  • Spinal Cord Injury — Typical likelihood, 46th percentile
  • Knee Injury — Typical likelihood, 45th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Joint Stiffness — Typical likelihood, 39th percentile
  • Rotator Cuff Injury — Typical likelihood, 38th percentile
  • Fractures — Typical likelihood, 37th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tendon Lining Inflammation — Typical likelihood, 36th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Toothache — Typical likelihood, 33th percentile
  • Stomach Pain — Typical likelihood, 27th percentile
  • Nerve Compression — Typical likelihood, 22th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Psoriatic Arthritis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • COL5A1 (Collagen) — Typical activity
  • Hyperparathyroidism — Typical likelihood
  • Vitamin D — Typical need
  • Phosphate — Typical levels
  • Magnesium — Typical need
  • VDR (Vitamin D) — Typical activity
  • CYP2R1 (Vitamin D) — Typical activity
  • Mononeuropathy — Typical likelihood
  • Peripheral Neuropathy — Typical likelihood
  • Neuropathic Pain — Typical likelihood
  • CNR1 (Cannabinoids) — Typical activity
  • SCN9A (Pain) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-9E9326
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-9E9326 · © 2026 Marrow Health.