Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 6 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Metabolic Health58 results reported of 61 analytes · 50 recommendations
Blood Sugar Control35 results reported of 38 analytes · 50 recommendations
Weight & Body Fat33 results reported of 33 analytes · 50 recommendations
Diet & Nutrition53 results reported of 118 analytes
Liver & Gallbladder Health25 results reported of 25 analytes · 50 recommendations
Cardiovascular Health82 results reported of 88 analytes · 50 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 228 results here, 27 came back worth discussing with a clinician and 15 came back in your favour. Bring this document to your appointment.
What this package looks at
Metabolic Health — Is your metabolism optimal? Maybe, but probably not. A recent study indicated that only about 1 in 8 people in the U.S. have optimal metabolic health [R].
Blood Sugar Control — Blood sugar control is essential for maintaining energy levels, supporting metabolic health, and preventing long-term complications. Genetic predispositions can significantly influence how well your body regulates blood sugar. These genetic factors may affect insulin sensitivity, glucose
Weight & Body Fat — Weight management and body fat distribution are influenced by a combination of environmental factors, lifestyle choices, and genetics. Genetic predispositions can significantly affect your tendency to gain or lose weight, how your body stores fat, and how efficiently your
Liver & Gallbladder Health — The liver is a vital organ that plays a central role in metabolism, detoxification, and overall bodily health. Genetic factors can significantly influence the liver's function and an individual's susceptibility to various liver conditions.
Cardiovascular Health — “Oh, my god! That will give you a heart attack!” said every cliche grandmother ever written. There is a notoriously long list for what “that” is, from high cholesterol to stress to weight. Unfortunately, people have a tendency to not worry about a health issue until it becomes a problem. So,
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Strength TrainingEngage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
Relates to: ADRB2 (Weight), Visceral Fat, Diabetic Neuropathy
2
Mediterranean DietLimit red meat to a few times a month and include a moderate amount of dairy products.
Relates to: Coronary Artery Disease, Artery Hardening, Peripheral Artery Disease, ApoB
3
Limit Calorie IntakeConsume fewer calories than your body needs for maintenance.
Relates to: UCP1 (Weight), Visceral Fat
4
Avoid Sugary Foods & DrinksAim to do this daily for ongoing health benefits.
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
5
Choose Healthy FatsAim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.
Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Lipoprotein(a)
6
Walking30 minutesIncorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
Relates to: Coronary Artery Disease, Peripheral Artery Disease, Artery Hardening, ApoB
7
Intermittent FastingLimit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.
Relates to: ADRB2 (Weight), Visceral Fat
8
Avoid Secondhand SmokeAvoid Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.
Relates to: Coronary Artery Disease, Artery Hardening, ApoB, Homocysteine
9
Sleep for 7+ HoursEnsure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
Relates to: Coronary Artery Disease, Heart Rate Recovery, Artery Hardening, ApoB
10
Limit Saturated FatReduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.
Relates to: Artery Hardening, Peripheral Artery Disease, Coronary Artery Disease, Lipoprotein(a)
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
MethylfolateRelates to: Homocysteine, Retinal Vein Occlusion, Coronary Artery Disease, Artery Hardening
2
BerberineRelates to: FOXO1 (Blood Sugar), TCF7L2 (Blood Sugar/Diet), GLP-1
3
ZincRelates to: SLC30A8 (Blood Sugar), Diabetic Foot Ulcers
4
Dietary Omega-3 Fatty AcidsRelates to: Heart Failure, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
Your headline findings
Of the 228 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Low Blood SugarMore likely
More likely to have low blood sugar based on 126,569 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Other non-diabetic risk factors include age, drinking alcohol, certain medications, severe infections, problems with your adrenal or pituitary gland, liver, kidney, or pancreas.
Other diabetic risk factors include taking too much diabetes medication, not eating enough or skipping meals, increasing physical activity without adjusting diet or medications, and drinking alcohol.
If you have high genetic risk, you may lower overall risk by taking action on those factors that you can change.
What you can do
- Regular Sleep Schedule
Aim for 7-9 hours of sleep per night. - Honey
Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.
From your Metabolic Health report & Blood Sugar Control
Varicose VeinsMore likely
More likely to have varicose veins based on 81,137 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Risk factors include: age, being female, overweight, sitting or standing most of the day, pregnancy, and childbirth.
If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.
Normal, healthy veins have many valves that keep the blood flowing in the right direction.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Apples
Incorporate at least one whole apple into your daily diet, either as a snack or part of your meals, ensuring to eat them consistently every day for an ongoing period to derive potential health benefits.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Cardiovascular Health report
Blood SpotsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
From your Cardiovascular Health report
PalpitationsMore likely
More likely to have palpitations based on 1,209,944 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: While no heritability percentage exists yet for this condition, genes involved may influence various heart functions.
Other risk factors include stress, anxiety, pregnancy, age, stimulants, overactive thyroid, and heart problems.
Experiencing palpitations are not uncommon, particularly because they can result from causes unrelated to heart conditions, like anxiety.
From your Cardiovascular Health report
Low Blood PressureMore likely
More likely to have low blood pressure based on 54,555 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: Genetics may play a role by influencing nervous system function, kidney function, and hormone activity.
Other risk factors include certain medications and health conditions.
It is estimated that up to 25% of adults may have low blood pressure.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Hazelnuts
Incorporate a handful of hazelnuts (about or) into your diet daily.
From your Cardiovascular Health report
Non-Viral HepatitisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.
What you can do
- Coffee
Drink 1 to 3 cups of black coffee daily, preferably in the morning to minimize potential sleep disturbances.
Ask your clinician about
- Taurine
- Milk Thistle (Silymarin)
Named only. Marrow gives no dose and does not recommend these.
From your Liver & Gallbladder Health report
Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.
What this actually is
Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.
Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.
The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.
What you can do
- Mediterranean Diet
Limit red meat to a few times a month and include a moderate amount of dairy products. - Choose Healthy Fats
Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings. - Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
From your Cardiovascular Health report
Heavy SweatingMore likely
More likely to have hyperhidrosis based on 104 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.
What this actually is
Key Takeaways: Genes that affect excessive sweating may influence nerve function and chemical messengers.
Excessive sweating can impact quality of life and cause undue stress and anxiety.
If you have symptoms, you may want to consult your doctor to rule out other conditions.
From your Metabolic Health report
A further 19 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.
Weight gain affects conditions like high blood sugar and heart disease.
However, it is highly modifiable by diet and exercise.
From your Metabolic Health report & Weight & Body Fat
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.
A history of diabetes in one's family.
A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.
From your Metabolic Health report & Blood Sugar Control, Weight & Body Fat, Cardiovascular Health
Alcoholic LiverLess likely
Less likely to have alcoholic liver disease based on 1,664 genetic variants we looked at
Your risk is greater than 13% of the population and lower than 87% of the population.
What this actually is
As ALD advances, the liver's ability to function properly diminishes, leading to serious health issues including jaundice, coagulopathy, and the buildup of toxins in the bloodstream that can affect brain function—a condition known as hepatic encephalopathy.
In late stages, patients may develop life-threatening complications such as ascites, which is the accumulation of fluid in the abdomen, and variceal bleeding due to increased pressure in the portal vein.
Abstinence from alcohol is the most critical factor in treatment and prevention of disease progression, accompanied by dietary changes and, in severe cases, the consideration for liver transplantation.
From your Liver & Gallbladder Health report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (19)
- Retinal Vein Occlusion — More likely, 90th percentile
- Coronary Artery Disease — More likely, 67th percentile
- ADRB2 (Weight) — Worse genetics
- TCF7L2 (Blood Sugar/Diet) — Worse genetics
- Diabetic Neuropathy — More likely
- Diabetic Foot Ulcers — More likely
- Diabetic Nephropathy — More likely
- Essential Amino Acids — Increased need
- Eating Habits — Increased need
- PNPLA3 (Lipids/ Liver Health) — Worse genetics
- Omega-6:Omega-3 Ratio — Increased need
- Sodium — Increased need
- Copper — Increased need
- FABP2 (Blood Sugar/ — Worse genetics
- Heart Failure — More likely
- Myocarditis — More likely
- Subarachnoid Hemorrhage — More likely
- Brain Hemorrhage — More likely
- Peripheral Artery Disease — More likely
Running above the typical range (25)
- ApoB — Higher levels, 99th percentile
- ADRB1 (Cardiovascular) — Higher activity, 92th percentile
- ALT — Higher levels, 88th percentile
- IRS1 (Metabolic Health) — Higher activity, 85th percentile
- Visceral Fat — Higher levels, 82th percentile
- Lipoprotein(a) — Higher levels, 81th percentile
- FOXO1 (Blood Sugar) — Higher activity
- MTNR1B (Diet & Blood Sugar) — Higher activity
- MC4R (Weight/ Blood Sugar) — Higher activity
- DIO1 (Thyroid) — Higher activity
- DIO2 (Thyroid) — Higher activity
- SUOX (PCOS/ Blood Sugar) — Higher activity
- LPL (Weight) — Higher activity
- AMY1A (Starch Digestion) — Higher activity
- Lycopene — Increased function
- Albumin — Higher levels
- Heart Rate Variability — Higher
- PCSK9 (Cholesterol) — Higher activity
- CELSR2-PSRC1-SORT1 (Cardiovascular) — Higher activity
- AGT (Cardiovascular & Fitness) — Higher activity
- GCH1 (Cardiovascular) — Higher activity
- LIPC (Cardiovascular) — Higher activity
- TMAO — Higher levels
- Homocysteine — Higher levels
- Platelet Aggregation — Higher
Running below the typical range (33)
- Belly Fat — Lower levels, 16th percentile
- Weight Loss from Calorie Restriction — Lower
- Metabolic Rate — Lower
- GLP-1 — Lower levels
- Postprandial Glucose — Lower levels
- SLC30A8 (Blood Sugar) — Lower activity
- UCP1 (Weight) — Lower activity
- CDKN2B (Blood Sugar) — Lower activity
- PPM1K (Blood Sugar/Diet) — Lower activity
- MADD (Blood Sugar & Insulin) — Lower activity
- ADCY5 (Blood Sugar) — Lower activity
- FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
- PLIN (Weight, Blood Sugar) — Lower activity
- Egg Allergy — Lower
- Shrimp Allergy — Lower
- Peanut Allergy — Lower
- Vitamin B12 — Lower levels
- Molybdenum — Lower levels
- Methionine — Lower levels
- Phenylalanine — Lower levels
- Lutein — Lower levels
- PDXK (Vitamin B6) — Lower activity
- GC (Vitamin D) — Lower activity
- TAS2R16 (Bitter Taste/ Longevity) — Lower activity
- FOLH1 (Folate/ Methylation) — Lower activity
- Bilirubin — Lower levels
- Heart Rate Recovery — Slower
- CPS1 (Cardiovascular, Kidney Health) — Lower activity
- DOCK7 (Blood Lipids) — Lower activity
- CETP (Cholesterol/ Longevity) — Lower activity
- ACE (Fitness/ Cardiovascular) — Lower activity
- MLXIPL (Triglycerides, Cardiovascular) — Lower activity
- SOAT1 (Cholesterol/ Cognition) — Lower activity
Working in your favour (12)
- Sugar Cravings — Less likely, 20th percentile
- FTO (Weight) — Better
- FTO (Overeating) — Better
- TMEM18 (Weight) — Better genetics
- IL6R (Weight) — Better genetics
- Fats Breakdown — Better
- Salicylate Sensitivity — Less likely
- Eating Disorders — Less likely
- Nutrition Genes — Less likely
- Liver Cirrhosis — Less likely
- Liver Failure — Less likely
- Mitral Valve Prolapse — Less likely
In line with most people (128)
- Peripheral Vascular Disease — Typical likelihood, 98th percentile
- Chronic Venous Insufficiency — Typical likelihood, 85th percentile
- Underweight — Typical likelihood, 79th percentile
- Weight Regain — Typical likelihood, 72th percentile
- Heart Arrhythmia — Typical likelihood, 67th percentile
- Gallstones — Typical likelihood, 66th percentile
- POTS — Typical likelihood, 65th percentile
- VLDL Cholesterol — Typical levels, 65th percentile
- Stroke — Typical likelihood, 63th percentile
- Venous Thromboembolism — Typical likelihood, 61th percentile
- Total Cholesterol — Typical levels, 61th percentile
- Cardiovascular Disease — Typical likelihood, 60th percentile
- Gout — Typical likelihood, 58th percentile
- Chest Pain (Angina) — Typical likelihood, 52th percentile
- Blood Clotting — Typical likelihood, 52th percentile
- High Blood Pressure — Typical likelihood, 51th percentile
- Type 2 Diabetes — Typical likelihood, 49th percentile
- Fatty Liver — Typical likelihood, 49th percentile
- Hashimoto's Disease — Typical likelihood, 47th percentile
- LDL Particle Number (LDL-P) — Typical, 47th percentile
- Overactive Thyroid — Typical likelihood, 46th percentile
- High Cholesterol — Typical likelihood, 46th percentile
- LDL Cholesterol — Typical levels, 44th percentile
- Insulin Resistance — Typical, 43th percentile
- ADRA2A (Blood Sugar) — Typical activity, 42th percentile
- Bile Duct Inflammation — Typical likelihood, 39th percentile
- Atrial Fibrillation — Typical likelihood, 39th percentile
- AST — Typical levels, 38th percentile
- Underactive Thyroid — Typical likelihood, 34th percentile
- Cold Hands and Feet (Raynaud's) — Typical likelihood, 31th percentile
- Reduced Bile Flow — Typical likelihood, 30th percentile
- Gallbladder Inflammation — Typical likelihood, 20th percentile
- Uric Acid — Typical levels, 16th percentile
- Type 1 Diabetes — Typical likelihood, 15th percentile
- Fasting Glucose — Typical levels
- HbA1c — Typical levels
- Insulin — Typical levels
- Graves' Disease — Typical likelihood
- TSH — Typical levels
- T3 (Triiodothyronine) — Typical levels
- T4 (Thyroxine) — Typical levels
- Free T4 — Typical levels
- Reverse T3 (rT3) — Typical levels
- Free T3 (fT3) — Typical levels
- Ketone Bodies — Typical levels
- Lactate — Typical levels
- Creatine — Typical levels
- LEPR (Weight/Leptin Resistance) — Typical activity
- ADIPOQ (Weight/ Blood Sugar) — Typical genetics
- UCP2 (Weight) — Typical activity
- UCP3 (Weight) — Typical activity
- ADRB3 (Weight) — Typical activity
- CD36 (Fat Preference/Weight) — Typical activity
- TFAP2B (Weight/Diet) — Typical activity
- PPARG (Metabolism) — Typical activity
- APOA2 (Weight, Blood Lipids) — Typical activity
- MC3R (Weight) — Typical activity
- TPO (Thyroid) — Typical
- PPARGC1A (Fitness/Blood Sugar) — Typical activity
- GCKR (Blood Sugar) — Typical activity
- GIPR (Blood Sugar) — Typical activity
- PPARA (Keto Diet) — Typical activity
- Diabetic Retinopathy — Typical likelihood
- CRY2 (Blood Sugar) — Typical genetics
- Adiponectin — Typical levels
- Ghrelin — Typical levels
- Leptin — Typical levels
- CLOCK (Sleep & Weight) — Typical activity
- PER2 (Dieting) — Typical genetics
- EPA (Omega-3) — Typical response
- DHA (Omega-3) — Typical response
- TA B L E O F C O N T E N T S — Typical levels
- Celiac Disease — Typical likelihood
- Dairy Sensitivity (Casein) — Typical likelihood
- PA G E 1 2 / 2 5 4 — Typical likelihood
- Minerals — Typical need
- FUT2 (Gut/ Vitamin B12) — Typical genetics
- PA G E 1 8 / 2 5 4 — Typical
- PUFA Response — Typical levels
- PA G E 4 7 / 2 5 4 — Typical likelihood
- Vitamin E — Typical need
- Thiamine (Vitamin B1) — Typical need
- Magnesium — Typical need
- Chromium — Typical levels
- PA G E 1 1 8 / 2 5 4 — Typical levels
- PA G E 1 2 9 / 2 5 4 — Typical likelihood
- PA G E 1 3 8 / 2 5 4 — Intermediate activity
- Liver Cancer — Typical likelihood
- Hepatitis B — Typical likelihood
- Hepatitis C — Typical likelihood
- Gallbladder Cancer — Typical likelihood
- Bile Duct Cancer — Typical likelihood
- Biliary Cirrhosis — Typical likelihood
- GGT — Typical levels
- Alkaline Phosphatase — Typical levels
- Choline — Typical need
- PEMT (Choline) — Typical activity
- CHDH (Choline) — Typical genetics
- ABCG8 (Cholesterol & Gallstones) — Typical activity
- Heart Attack — Typical likelihood
- Rheumatic Heart Disease — Typical likelihood
- Aortic Stenosis — Typical likelihood
- Dilated Cardiomyopathy — Typical likelihood
- Hypertrophic Cardiomyopathy — Typical likelihood
- Aortic Valve Calcification — Typical likelihood
- Aortic Aneurysm — Typical likelihood
- Brain Aneurysm — Typical likelihood
- Cerebral Small Vessel Disease — Typical likelihood
- Brain Ischemia — Typical likelihood
- Vasculitis — Typical likelihood
- Deep Vein Thrombosis — Typical likelihood
- Heart Rate — Typical
- Tachycardia — Typical likelihood
- Bradycardia — Typical likelihood
- Salt Sensitivity — Typical
- Pulmonary Hypertension — Typical likelihood
- APOC3 (Blood Lipids/ Longevity) — Typical activity
- NOS3 (Cardiovascular) — Typical activity
- HMGCR (Cholesterol) — Typical activity
- APOB Gene (Cardiovascular) — Typical activity
- ABCA1 (Cholesterol) — Typical genetics
- LPA (Blood Lipids & Heart Health) — Typical activity
- LDLR (Cholesterol, Cardiovascular) — Typical activity
- LDL Particle Size — Typical
- Lp-PLA2 — Typical levels
- Platelets — Typical levels
- Response to Ezetimibe — Typical
- Response to Statins (Functional) — Typical response
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.