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Genomics · Genetic Reports · Precision Wellness

Nerve Health Package

Personalized 3-Report Genetic Package
Nerve HealthPainHeadaches & Migraines
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-5F89C9
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-5F89C9
Reports in package
3
Results scored
55 of 74
Need attention
15
Report
Summary Report

The reports inside this package

This one document contains 3 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Nerve Health30 results reported of 36 analytes · 50 recommendations
Pain33 results reported of 33 analytes · 50 recommendations
Headaches & Migraines5 results reported of 5 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 55 results here, 15 came back worth discussing with a clinician and 3 came back in your favour. Bring this document to your appointment.

What this package looks at

Nerve Health — Nerve health plays a vital role in overall well-being, affecting everything from movement and sensation to cognition and emotional balance. Genetics can significantly influence an individual's susceptibility to various nerve-related conditions, impacting both the peripheral and central

Pain — We all experience pain from time to time, from stubbing a toe to hurting our knee or having a migraine attack. What makes us all different is the amount of pain we experience and how we handle it. There are lots of reasons for that, one of which is your DNA!

Headaches & Migraines — Headaches and migraines are common issues that can significantly impact daily life, leading to discomfort, pain, and reduced productivity. While environmental factors such as stress, sleep patterns, and diet can trigger headaches, genetics also plays an essential role in determining an

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Food Triggers

Try to limit caffeine to per day to avoid migraines.

Relates to: Migraines
relevance
2
Avoid Sensory Triggers

Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.

Relates to: Migraines
relevance
3
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Parkinson's Disease, Shoulder & Neck Pain, Diabetic Neuropathy
relevance
4
Nerve Stimulation30 minutes

Nerve stimulation can be implemented by daily sessions of 15-30 minutes using a device specifically designed for TA this purpose.

Relates to: Cluster Headaches, Migraines
relevance
5
Sleep for 7+ Hours

Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.

Relates to: Migraines, Cluster Headaches
relevance
6
Cognitive-Behavioral Therapy (CBT)

Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Relates to: Migraines, Chronic Pain, Fibromyalgia, Shoulder & Neck Pain
relevance
7
Biofeedback

Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.

Relates to: Diabetic Neuropathy, Chronic Pain, Migraines, Shoulder & Neck Pain
relevance
8
Yoga30 minutes

Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Relates to: Parkinson's Disease, Shoulder & Neck Pain, Chronic Pain, Fibromyalgia
relevance
9
Dance30 minutes

Engage in dance activities for at least 30 minutes, three times per week.

Relates to: Parkinson's Disease
relevance
10
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Long COVID
relevance
11
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Chronic Pain, Migraines, Long COVID, Shoulder & Neck Pain
relevance
12
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Chronic Pain, Shoulder & Neck Pain, Diabetic Neuropathy, Fibromyalgia
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Magnesium
Relates to: Migraines, Cluster Headaches
relevance
2
Methylfolate
Relates to: Parkinson's Disease
relevance

Your headline findings

Of the 55 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

MigrainesMore likely
More likely to have migraines based on 109,603 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: obesity, depression, stress, being female, blood vessel issues, brain chemical imbalances.

If you have a high genetic risk, take action on modifiable risk factors to help reduce overall risk.

About 16% of Americans regularly have migraines.

What you can do

  • Avoid Food Triggers
    Try to limit caffeine to per day to avoid migraines.
  • Avoid Sensory Triggers
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Sleep for 7+ Hours
    Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
From your Pain report & Headaches & Migraines
Facial PainMore likely
Higher predisposition than 98% of people
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Diagnosing facial approach that can otolaryngologists, comprehensively and strategies could blocks, or surgery, For instance, sudden, severe resulting from Psychological also play pivotal the need for a plan.

What you can do

  • Biofeedback
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
  • Massage 30 minutes
    Choose a type of TA massage that suits your specific needs, such as Swedish for relaxation or deep tissue for muscle tension.
From your Nerve Health report & Pain
Droopy EyelidsMore likely
More likely to have droopy eyelids based on 240,468 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Eyelid drooping is excess sagging of the upper eyelid.

The eyelid may be sitting lower than it should (ptosis) or drooping due to loose or excess skin (dermatochalasis).

About 60% of the differences in people’s eyelid drooping may be due to genetics.

From your Nerve Health report
Ear PainMore likely
Higher predisposition than 94% of people
Your risk is greater than 94% of the population and lower than 6% of the population.

What this actually is

Ear pain may not itself; it can conditions that otalgia.

Sinus dental issues, and to the ear.

Diagnosis of the comprehensive exam, audiometric studies.

What you can do

  • Apply Heat 15 minutes
    Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.
  • Topical Peppermint Oil
    Do this no more than 2-3 times daily.
From your Pain report
Statin-Induced Muscle PainMore likely
More likely to have statin-induced muscle pain based on 38 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

The exact mechanism by which statins cause muscle injury is not completely understood, but it is believed to be related to the depletion of coenzyme Q10, a key component in muscle energy production, or effects on muscle cell membranes and protein synthesis.

Risk factors for developing statin-induced myopathy include higher statin dosages, advanced age, female sex, smaller body frame, concurrent use of certain medications, and pre-existing conditions such as kidney disease.

Most patients see improvement in symptoms after discontinuation of the statin, but the condition necessitates careful balancing of the benefits of cholesterol lowering against the discomfort and potential harm of muscle symptoms.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Coenzyme Q10 (CoQ10)

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Painful UrinationMore likely
More likely to have painful urination based on 786,605 genetic variants we looked at
Your risk is greater than 88% of the population and lower than 12% of the population.

What this actually is

Apart from other conditions or obstruct the flow prostate issues hyperplasia (BPH) infections or contribute to Other contributors certain harsh soaps or crucial when depends on cause.

What you can do

  • Drink at Least 8 Glasses of Water a Day
    Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.
  • Apply Heat 15 minutes
    Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.
From your Pain report
Shoulder & Neck PainMore likely
More likely to have shoulder and neck pain based on 924,669 genetic variants we looked at
Your risk is greater than 84% of the population and lower than 16% of the population.

What this actually is

Key Takeaways: About 1 in 5 adults have neck or shoulder pain.

Other risk factors include: poor posture, prolonged sitting, poor sleep position, injury and overuse, stress, and older age.

If you have high genetic risk or are experiencing symptoms, take action on modifiable factors like posture and sleep position.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
From your Pain report
TremorMore likely
More likely to have tremors based on 26,737 genetic variants we looked at
Your risk is greater than 82% of the population and lower than 18% of the population.

What this actually is

The severity of a tremor can vary, from a slight quiver that is essentially a cosmetic concern to a more severe disruption that can impair one's ability to perform daily tasks.

can be classified by its appearance and cause or its origin.

There are several forms of tremor, including essential tremor, parkinsonian tremor, and dystonic tremor, each with distinctive features and patterns.

What you can do

  • Tai Chi
    Practice Tai Chi for 30 to 60 minutes at least twice a week.

Ask your clinician about

  • Ginkgo

Named only. Marrow gives no dose and does not recommend these.

From your Nerve Health report
A further 7 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.

About 60-70% of the differences in people’s cognitive decline may come from genetics.

For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].

From your Nerve Health report
Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Pain report
Speech DisorderLess likely
Lower predisposition than 86% of people
Your result sits lower than 86% of the population.

What this actually is

Living with aphasia can be challenging, not only for those affected but also for their family and friends.

It often leads to social isolation and frustration due to the barriers it creates in everyday communication.

Therapy for aphasia primarily involves speech and language exercises that aim to improve the individual's ability to Less likely to have communicate.

From your Nerve Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (7)
  • Cluster Headaches — More likely, 82th percentile
  • Chronic Pain — More likely, 80th percentile
  • Parkinson's Disease — More likely, 70th percentile
  • Diabetic Neuropathy — More likely
  • Painful Bladder Syndrome — More likely
  • Fibromyalgia — More likely
  • Long COVID — More likely
Running above the typical range  (2)
  • TRPM8 (Pain) — Higher activity
  • KIBRA/WWC1 (Cognition) — Higher activity
Running below the typical range  (3)
  • TRPV1 (Pain) — Lower activity, 15th percentile
  • ENPP6 (Cognition) — Lower activity
  • OPRM1 (Endorphins) — Lower activity
In line with most people  (32)
  • Back Pain — Typical likelihood, 76th percentile
  • Painful Intercourse — Typical likelihood, 74th percentile
  • Trigeminal Nerve Pain — Typical likelihood, 68th percentile
  • Muscle Pain — Typical likelihood, 68th percentile
  • Alzheimer's Disease — Typical likelihood, 65th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Tension Headaches — Typical likelihood, 64th percentile
  • Stroke — Typical likelihood, 63th percentile
  • Burning Mouth Syndrome — Typical likelihood, 62th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Headache — Typical likelihood, 51th percentile
  • Difficulty Swallowing — Typical likelihood, 43th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tics — Typical likelihood, 33th percentile
  • Toothache — Typical likelihood, 33th percentile
  • Stomach Pain — Typical likelihood, 27th percentile
  • Paresthesia — Typical likelihood, 23th percentile
  • Nerve Compression — Typical likelihood, 22th percentile
  • Brain Cancer — Typical likelihood
  • Brain Ischemia — Typical likelihood
  • Dystonia — Typical likelihood
  • Seizures — Typical likelihood
  • Neuropathic Pain — Typical likelihood
  • Peripheral Neuropathy — Typical likelihood
  • Bell's Palsy — Typical likelihood
  • IDO (Kynurenine) — Typical levels
  • SCN9A (Pain) — Typical activity
  • Mononeuropathy — Typical likelihood
  • CNR1 (Cannabinoids) — Typical activity
  • DAO (Histamine) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-5F89C9
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-5F89C9 · © 2026 Marrow Health.