Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 3 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Sleep15 results reported of 22 analytes · 50 recommendations
Fatigue43 results reported of 43 analytes · 50 recommendations
Mood & Mental Health62 results reported of 65 analytes · 50 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 102 results here, 20 came back worth discussing with a clinician and 7 came back in your favour. Bring this document to your appointment.
What this package looks at
Sleep — At one point or another, we’ve all tossed and turned in bed, desperately trying to get some much needed rest. Trouble sleeping can lead to chronic tiredness, irritability, difficulty concentrating, and a general lack of energy [R].
Fatigue — Sluggish, can’t think straight, and tired most of the day? Or is it just at certain times? Fatigue is a normal part of life, but it can also be a serious health issue. Chronic fatigue is one of those things that is easy to brush off, because, “Hey! Everyone gets tired.” However, chronic fatigue is a
Mood & Mental Health — Mental health and mood regulation are influenced by a combination of environmental factors and genetics. Recent advances in genetic research have unveiled how specific genes and biomarkers may predispose individuals to various mental health conditions, mood disorders, and
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Airflow DevicesUse an airflow device, such as a continuous positive airway pressure (CPAP) machine, every night during sleep.
Relates to: Sleep Apnea, Snoring
2
PsychotherapySchedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Relates to: Low Mood, Bipolar Disorder, Obsessive-Compulsive Tendencies, Psychological Trauma
3
Cognitive-Behavioral Therapy (CBT)Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Relates to: Low Mood, CRHR2 (Stress/HPA Axis), Obsessive-Compulsive Tendencies, Bipolar Disorder
4
Sleep for 7+ HoursEnsure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
Relates to: Brain Fog, Low Mood, Heart Rate Recovery
5
Interpersonal Therapy50 minutesEngage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.
Relates to: Low Mood, Eating Disorders
6
Psychodynamic TherapyPsychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
Relates to: Low Mood, Psychological Trauma, Eating Disorders, Anger
7
Sunlight Exposure20 minutesExpose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.
Relates to: Low Mood, Bipolar Disorder, DRD2 (Dopamine), RGS2 (Anxiety)
8
Hyperbaric Oxygen Therapy90 minutesSchedule and attend sessions in a hyperbaric oxygen therapy chamber as your doctor prescribes, typically for TA about 60 to 90 minutes per session.
Relates to: Sleep Apnea
9
Strength TrainingEngage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
Relates to: Low Mood, Heart Rate Recovery, Frailty
10
Meditation30 minutesSet aside 10-20 minutes each day in a quiet space without distractions to practice meditation.
Relates to: RGS2 (Anxiety), Low Mood, Psychological Trauma, DRD2 (Dopamine)
11
Mindfulness Meditation30 minutesTA focus on your breath, observing thoughts and sensations without judgment.
Relates to: RGS2 (Anxiety), Low Mood, Obsessive-Compulsive Tendencies, Agoraphobia
12
Airway Muscle Training30 minutesPerform airway muscle training exercises daily for at least 30 minutes.
Relates to: Sleep Apnea, Snoring
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
TryptophanRelates to: Low Mood, MAOB (Dopamine/ Norepinephrine), Bipolar Disorder, Mania
2
Acetyl-L-CarnitineRelates to: Low Mood, Fibromyalgia, Brain Fog
Your headline findings
Of the 102 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
ManiaMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
What this actually is
Risk factors for mania include: Bipolar disorder Family history Stress Drug use Sleep deprivation More likely to genetic Treating mania typically involves a combination of medication, psychotherapy, and lifestyle adjustments.
Mood stabilizers such as lithium, anticonvulsants like valproate or carbamazepine, and atypical antipsychotics are often prescribed to manage manic episodes and prevent their recurrence.
Psychotherapy, particularly cognitive-behavioral therapy (CBT) or psychoeducation, can help individuals recognize triggers, Your risk develop coping strategies, and improve insight into their and condition.
What you can do
- Yoga 30 minutes
Practice yoga for at least 20 to 30 minutes a day, most days of the week. - Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Mood & Mental Health report
Eating DisordersMore likely
More likely to have an eating disorder based on 11,026 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Other risk factors include dieting, major stressful events, and other mental health conditions.
If you have symptoms, talk to a healthcare professional.
About 1% of people may develop an eating disorder at some point in their life.
What you can do
- Psychotherapy
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress. - Yoga 30 minutes
Practice yoga for at least 20 to 30 minutes a day, most days of the week. - Neurofeedback
Attend neurofeedback sessions with a trained therapist, usually once or twice a week, for a minimum of 20 TA sessions.
From your Mood & Mental Health report
Binge EatingMore likely
More likely to binge eat based on 13,449 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.
What this actually is
Binge eating can be associated with: Psychological issues: Low self-esteem, body dissatisfaction, and significant stress can trigger binge eating.
Biological factors: Genetic mutations may affect hunger and satiety, through alterations in brain chemistry that can predispose individuals to eating disorders.
Social and cultural factors: Dysfunctional family dynamics, professions and activities that focus on appearance and dieting, and traumatic situations such as bullying or abuse can increase the risk of BED.
What you can do
- Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life. - Psychodynamic Therapy
Psychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
From your Mood & Mental Health report
Brain FogMore likely
More likely to have brain fog based on 5,554 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.
What this actually is
Key Takeaways: Brain fog is a common symptom of chronic fatigue syndrome.
It manifests as memory problems, difficulty focusing, jumbled or hazy thoughts, and confusion.
Risk factors include stress, sleep problems, air pollution, smoking, and your genetics.
What you can do
- Sleep for 7+ Hours
Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night. - Yoga 30 minutes
Practice yoga for at least 20 to 30 minutes a day, most days of the week. - Dark Chocolate
Eat dark chocolate with a cocoa content of at least 70-85%, limiting intake to about a day to gain cardiovascular and mood-related benefits without excessive calorie intake.
From your Fatigue report
Guilty FeelingsMore likely
More likely to have guilty feelings based on 508,257 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.
What this actually is
Chronic or excessive feelings of guilt can be particularly debilitating, leading to a well-documented decline in psychological well-being.
It can manifest in physical symptoms such as insomnia, loss of appetite, or gastrointestinal distress due to the close connection between mental and physical health.
In some cases, persistent guilt may also contribute to the development of mental health conditions such as depression, anxiety disorders, and compulsive behaviors.
From your Mood & Mental Health report
Borderline PersonalityMore likely
More likely to have BPD based on 17,840 genetic variants we looked at
Your risk is greater than 93% of the population and lower than 7% of the population.
What this actually is
Factors that might increase the risk of developing BPD include: Childhood abandonment, neglect, or abuse A family history of BPD or other mental health disorders Brain abnormalities, particularly in regions related to emotion regulation, impulsivity, and aggression Neurochemical imbalances in the brain Genetics There is evidence suggesting that genetics plays a role in BPD development.
Having a close family member, such as a parent or sibling, with the disorder can increase the risk of developing BPD.
Research has indicated that certain genetic variants might be linked to BPD, affecting how the brain regulates emotions and impulsivity.
What you can do
- Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life. - Psychodynamic Therapy
Psychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Mood & Mental Health report
Sleep ApneaMore likely
More likely to have sleep apnea based on 1,227,186 genetic variants we looked at
Your risk is greater than 92% of the population and lower than 8% of the population.
What this actually is
Key Takeaways: About 10-40% of differences in people's chances of developing sleep apnea may be due to genetics.
Other important risk factors include being male, older, overweight, nasal congestion issues, a smoker, and drinking alcohol.
Sleep apnea is a disorder that interrupts your breathing while you sleep.
What you can do
- Airflow Devices
Use an airflow device, such as a continuous positive airway pressure (CPAP) machine, every night during sleep. - Hyperbaric Oxygen Therapy 90 minutes
Schedule and attend sessions in a hyperbaric oxygen therapy chamber as your doctor prescribes, typically for TA about 60 to 90 minutes per session. - Airway Muscle Training 30 minutes
Perform airway muscle training exercises daily for at least 30 minutes.
From your Sleep report & Fatigue
Obsessive-Compulsive TendenciesMore likely
Higher predisposition than 92% of people
Your result sits higher than 92% of the population.
What you can do
- Psychotherapy
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress. - Cognitive-Behavioral Therapy (CBT)
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life. - Mindfulness Meditation 30 minutes
TA focus on your breath, observing thoughts and sensations without judgment.
From your Mood & Mental Health report
A further 12 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Muscle SorenessLess likely
Less likely to experience muscle soreness based on 6 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.
What this actually is
Management of muscle soreness includes: Rest: Allowing muscles time to recover is crucial; gentle stretching can also help.
Proper nutrition and hydration: Eating a balanced diet rich in antioxidants and staying hydrated can support muscle recovery.
Ice Packs: Applying ice packs in the first 24-72 hours can help reduce inflammation.
From your Fatigue report
Daytime SleepinessLess likely
Less likely to experience daytime sleepiness based on 999,088 genetic variants we looked at
What this actually is
Daytime sleepiness is the feeling of excessive sleepiness during the day.
People with excessive daytime sleepiness often complain of not feeling well-rested, having difficulty waking up, or accidentally falling asleep during the day, among others [R, R, R].
Daytime sleepiness is usually a consequence of poor sleep duration or quality.
From your Sleep report & Fatigue
Pernicious AnemiaLess likely
Lower predisposition than average
What this actually is
Pernicious anemia variety of symptoms These include: Fatigue and Pale or Heart Shortness of Nerve problems weakness, and Mental problems behavioral Glossitis and Left untreated, it The primary administration of frequently (often stabilize.
For administration may intake is not reduced dietary Regular monitoring vitamin B12 levels help prevent adjustments to foods or alone cannot lacking.
From your Fatigue report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (12)
- Anger — More likely, 90th percentile
- Psychological Trauma — More likely, 90th percentile
- Frailty — More likely, 89th percentile
- Agoraphobia — More likely, 88th percentile
- Low Mood — More likely, 85th percentile
- Snoring — More likely, 84th percentile
- Bipolar Disorder — More likely, 75th percentile
- NPAS2 (Mood/ Sleep Schedule) — Worse genetics
- Fibromyalgia — More likely
- Long COVID — More likely
- Emotional Blindness — More likely
- GAD1 (Glutamate/GABA) — Worse
Running above the typical range (11)
- Irritability — Higher, 95th percentile
- MCHC — Higher levels, 90th percentile
- Hematocrit — Higher levels
- Hemoglobin — Higher levels
- Ferritin — Higher levels
- Endurance — Higher
- DRD3 (Dopamine/Energy) — Higher activity
- MAOB (Dopamine/ Norepinephrine) — Higher activity
- HTR1A (Serotonin) — Higher activity
- OXTR (Oxytocin) — Higher activity
- KIBRA/WWC1 (Cognition) — Higher activity
Running below the typical range (11)
- Heart Rate Recovery — Slower
- Tolerance to Exercise Intensity — Lower
- SLC6A4 (Fatigue, Mental Health) — Lower activity
- IL1B (Inflammation/ Fatigue) — Lower activity
- CRHR2 (Stress/HPA Axis) — Lower activity
- RGS2 (Anxiety) — Lower activity
- CRHR1 (Stress/HPA Axis) — Lower activity
- FKBP5 (Stress/ HPA Axis) — Lower activity
- GABA-A — Lower activity
- DRD2 (Dopamine) — Lower activity
- FAAH (Cannabinoids) — Lower activity
Working in your favour (4)
- Anhedonia — Less likely
- Caffeine-Related Anxiety — Less likely
- Neurodivergence — Less likely
- Delirium — Less likely
In line with most people (53)
- Stress — Typical likelihood, 74th percentile
- Phobias — Typical likelihood, 74th percentile
- Hair Pulling — Typical likelihood, 74th percentile
- Anemia — Typical likelihood, 70th percentile
- Worrying — Typical likelihood, 70th percentile
- Seasonal Low Mood — Typical likelihood, 65th percentile
- Schizophrenia — Typical likelihood, 63th percentile
- MCH — Typical levels, 60th percentile
- Muscle Cramps — Typical likelihood, 59th percentile
- Low Energy (Chronic Fatigue) — Typical likelihood, 58th percentile
- Night Peeing — Typical likelihood, 57th percentile
- Anxiety — Typical likelihood, 57th percentile
- Panic Attacks — Typical likelihood, 57th percentile
- SNAP25 (Mental Health) — Typical activity, 50th percentile
- Insomnia — Typical likelihood, 47th percentile
- Aggression — Typical, 46th percentile
- Psychosis — Typical likelihood, 46th percentile
- Social Anxiety — Typical likelihood, 37th percentile
- Tics — Typical likelihood, 33th percentile
- Restless Legs — Typical likelihood, 27th percentile
- Sleep Duration — Typical
- Sleep Quality — Typical
- Sleep Latency — Typical
- Sleep Movement — Typical likelihood
- Caffeine-Related Sleep Problems — Typical likelihood
- Narcolepsy — Typical likelihood
- CLOCK (Sleep & Weight) — Typical activity
- GRIA3 (Sleep/Mood) — Typical activity
- Iron — Typical need
- Red Blood Cells — Typical levels
- Aplastic Anemia — Typical likelihood
- TIBC — Typical levels
- MPV — Typical levels
- RDW — Typical levels
- MCV — Typical levels
- Exercise Recovery — Typical
- Aerobic Capacity (VO2 Max) — Typical
- Muscle Recovery — Typical
- TMPRSS6 (Iron) — Typical activity
- NR3C1 (Fatigue) — Intermediate activity
- TF (Iron & Cognition) — Typical activity
- Nervousness — Typical
- Cortisol — Typical levels
- Response to Stress (Functional) — Typical response
- ADORA2A (Anxiety) — Typical activity
- Nail Biting — Typical likelihood
- GSK3B (Serotonin) — Typical activity
- HTR2A (Serotonin) — Typical activity
- TPH2 (Serotonin) — Typical activity
- CNR1 (Cannabinoids) — Typical activity
- SLC6A2 (Mental Health) — Typical activity
- DBH (Mental Health) — Typical activity
- SLC6A3 (Mental Health) — Typical activity
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.