Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
The reports inside this package
This one document contains 5 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
Weight & Body Fat33 results reported of 33 analytes · 50 recommendations
Metabolic Health58 results reported of 61 analytes · 50 recommendations
Blood Sugar Control35 results reported of 38 analytes · 50 recommendations
Diet & Nutrition53 results reported of 118 analytes
Amino Acids28 results reported of 28 analytes · 50 recommendations
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 150 results here, 14 came back worth discussing with a clinician and 11 came back in your favour. Bring this document to your appointment.
What this package looks at
Weight & Body Fat — Weight management and body fat distribution are influenced by a combination of environmental factors, lifestyle choices, and genetics. Genetic predispositions can significantly affect your tendency to gain or lose weight, how your body stores fat, and how efficiently your
Metabolic Health — Is your metabolism optimal? Maybe, but probably not. A recent study indicated that only about 1 in 8 people in the U.S. have optimal metabolic health [R].
Blood Sugar Control — Blood sugar control is essential for maintaining energy levels, supporting metabolic health, and preventing long-term complications. Genetic predispositions can significantly influence how well your body regulates blood sugar. These genetic factors may affect insulin sensitivity, glucose
Amino Acids — Understanding the genetic predisposition for amino acid levels and needs is crucial for tailoring individual health and nutritional plans. This report delves into how genetic variations can influence the body's ability to absorb, produce, and use amino acids, potentially impacting overall
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Strength TrainingEngage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
Relates to: ADRB2 (Weight), Homocysteine, Visceral Fat, Diabetic Neuropathy
2
Dietary B VitaminsRelates to: Homocysteine
3
Limit Calorie IntakeConsume fewer calories than your body needs for maintenance.
Relates to: UCP1 (Weight), FOXO1 (Blood Sugar), Visceral Fat
4
Avoid Sugary Foods & DrinksAim to do this daily for ongoing health benefits.
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
5
Intermittent FastingLimit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.
Relates to: ADRB2 (Weight), GLP-1, Visceral Fat, FOXO1 (Blood Sugar)
6
Mediterranean DietLimit red meat to a few times a month and include a moderate amount of dairy products.
Relates to: TCF7L2 (Blood Sugar/Diet), Visceral Fat
7
High-Intensity Interval Training (HIIT)30 minutesEngage in HIIT workouts for at least 30 minutes per session, 3 times a week.
Relates to: Visceral Fat
8
Keto DietAdopt a diet that consists of about 70-80% fat, 10-20% protein, and 5-10% carbohydrates.
Relates to: Visceral Fat
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
MethylfolateRelates to: Homocysteine
2
Vitamin B12Relates to: Homocysteine
3
BerberineRelates to: FOXO1 (Blood Sugar), TCF7L2 (Blood Sugar/Diet), GLP-1
4
ZincRelates to: SLC30A8 (Blood Sugar), Homocysteine, Diabetic Foot Ulcers
5
Omega-3 (Fish Oil)Relates to: Homocysteine
6
Betaine (TMG)Relates to: Homocysteine
Your headline findings
Of the 150 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Low Blood SugarMore likely
More likely to have low blood sugar based on 126,569 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Other non-diabetic risk factors include age, drinking alcohol, certain medications, severe infections, problems with your adrenal or pituitary gland, liver, kidney, or pancreas.
Other diabetic risk factors include taking too much diabetes medication, not eating enough or skipping meals, increasing physical activity without adjusting diet or medications, and drinking alcohol.
If you have high genetic risk, you may lower overall risk by taking action on those factors that you can change.
What you can do
- Regular Sleep Schedule
Aim for 7-9 hours of sleep per night. - Honey
Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.
From your Metabolic Health report & Blood Sugar Control
Heavy SweatingMore likely
More likely to have hyperhidrosis based on 104 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.
What this actually is
Key Takeaways: Genes that affect excessive sweating may influence nerve function and chemical messengers.
Excessive sweating can impact quality of life and cause undue stress and anxiety.
If you have symptoms, you may want to consult your doctor to rule out other conditions.
From your Metabolic Health report
ADRB2 (Weight)Worse genetics
Higher predisposition than average
What this actually is
The rs1042714 variant (also known as Q27E or Gln27Glu) has been most widely researched when it comes to weight.
Its minor ‘G’ allele (Glu, E) was associated with approximately 20% higher odds of obesity in a meta-analysis of 18 studies.
An older meta-analysis came to a similar conclusion.
What you can do
- Strength Training
Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week. - Intermittent Fasting
Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Weight & Body Fat report & Metabolic Health
TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average
What this actually is
The two main TCF7L2 variants are rs7903146 and rs12255372.
They are almost always inherited together, which means they act as a single genetic factor.
Their "T" alleles have one of the strongest known links with type 2 diabetes.
What you can do
- Avoid Sugary Foods & Drinks
Aim to do this daily for ongoing health benefits. - Avoid Sugary Foods & Drinks
Aim to do this daily for ongoing health benefits. - Mediterranean Diet
Limit red meat to a few times a month and include a moderate amount of dairy products.
From your Metabolic Health report & Blood Sugar Control
Diabetic NeuropathyMore likely
More likely to have diabetic neuropathy based on 1,658 genetic variants we looked at
What this actually is
Prolonged exposure to high blood sugar levels is the primary cause of diabetic neuropathy.
However, other factors that might increase the risk or severity of diabetic neuropathy include: Smoking Alcohol abuse Obesity High blood pressure Kidney disease Genetics Specific genetic variations might render some individuals more vulnerable to the neurotoxic effects of high blood sugar.
Hence, while some people with diabetes may never develop neuropathy, others might face complications even with good glucose control.
Ask your clinician about
- Alpha-Lipoic Acid
- Tocotrienols
- Coenzyme Q10 (CoQ10)
Named only. Marrow gives no dose and does not recommend these.
From your Blood Sugar Control report
Diabetic Foot UlcersMore likely
Higher predisposition than average
What this actually is
The following factors may increase the risk of diabetic foot ulcers: Peripheral neuropathy, which reduces the ability to feel pain and detect injuries.
Poor blood circulation, which compromises skin health and healing ability.
Foot deformities, which increase the risk of pressure sores.
What you can do
- Infrared Light Therapy
After one month, the patients’ ulcers shrank in size and had fewer secretions. - Honey
Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Blood Sugar Control report
Diabetic NephropathyMore likely
More likely to have diabetic nephropathy based on 28,985 genetic variants we looked at
What this actually is
Factors linked to an increased risk of diabetic nephropathy include: Poorly controlled blood sugar levels High blood pressure Long duration of diabetes Smoking Obesity Family history of kidney disease High cholesterol levels Managing diabetic nephropathy involves controlling blood sugar and blood pressure, alongside lifestyle changes.
Common treatments include: Medications: ACE inhibitors or ARBs to control blood pressure, blood sugar-lowering drugs, and statins for cholesterol management.
Dietary changes: Low-protein and low-sodium diets to reduce kidney strain.
What you can do
- Okra
- Avoid Organochlorine Pesticide Exposure
Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Blood Sugar Control report
Essential Amino AcidsIncreased need
Higher predisposition than average
From your Diet & Nutrition report
A further 6 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.
Weight gain affects conditions like high blood sugar and heart disease.
However, it is highly modifiable by diet and exercise.
From your Weight & Body Fat report & Metabolic Health
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.
A history of diabetes in one's family.
A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.
From your Weight & Body Fat report & Metabolic Health, Blood Sugar Control
Sugar CravingsLess likely
Less likely to crave sugar based on 673,476 genetic variants we looked at
Your risk is greater than 20% of the population and lower than 80% of the population.
What this actually is
People who have less sensitive sweet receptors may have a “sweet tooth.” They may prefer sweet foods and eat more of them [R, R, R].
From your Blood Sugar Control report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (6)
- Eating Habits — Increased need
- PNPLA3 (Lipids/ Liver Health) — Worse genetics
- Omega-6:Omega-3 Ratio — Increased need
- Sodium — Increased need
- Copper — Increased need
- FABP2 (Blood Sugar/ — Worse genetics
Running above the typical range (15)
- IRS1 (Metabolic Health) — Higher activity, 85th percentile
- Visceral Fat — Higher levels, 82th percentile
- LPL (Weight) — Higher activity
- MC4R (Weight/ Blood Sugar) — Higher activity
- AMY1A (Starch Digestion) — Higher activity
- FOXO1 (Blood Sugar) — Higher activity
- MTNR1B (Diet & Blood Sugar) — Higher activity
- DIO1 (Thyroid) — Higher activity
- DIO2 (Thyroid) — Higher activity
- SUOX (PCOS/ Blood Sugar) — Higher activity
- Lycopene — Increased function
- Leucine — Higher levels
- Valine — Higher levels
- Alanine — Higher levels
- Homocysteine — Higher levels
Running below the typical range (24)
- Belly Fat — Lower levels, 16th percentile
- Weight Loss from Calorie Restriction — Lower
- Metabolic Rate — Lower
- UCP1 (Weight) — Lower activity
- PLIN (Weight, Blood Sugar) — Lower activity
- GLP-1 — Lower levels
- Postprandial Glucose — Lower levels
- SLC30A8 (Blood Sugar) — Lower activity
- CDKN2B (Blood Sugar) — Lower activity
- PPM1K (Blood Sugar/Diet) — Lower activity
- MADD (Blood Sugar & Insulin) — Lower activity
- ADCY5 (Blood Sugar) — Lower activity
- FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
- Egg Allergy — Lower
- Shrimp Allergy — Lower
- Peanut Allergy — Lower
- Vitamin B12 — Lower levels
- Molybdenum — Lower levels
- Methionine — Lower levels
- Lutein — Lower levels
- PDXK (Vitamin B6) — Lower activity
- GC (Vitamin D) — Lower activity
- TAS2R16 (Bitter Taste/ Longevity) — Lower activity
- FOLH1 (Folate/ Methylation) — Lower activity
Working in your favour (8)
- FTO (Overeating) — Better
- FTO (Weight) — Better
- TMEM18 (Weight) — Better genetics
- IL6R (Weight) — Better genetics
- Fats Breakdown — Better
- Salicylate Sensitivity — Less likely
- Eating Disorders — Less likely
- Nutrition Genes — Less likely
In line with most people (86)
- Underweight — Typical likelihood, 79th percentile
- Weight Regain — Typical likelihood, 72th percentile
- Gout — Typical likelihood, 58th percentile
- Isoleucine — Typical levels, 56th percentile
- Type 2 Diabetes — Typical likelihood, 49th percentile
- Hashimoto's Disease — Typical likelihood, 47th percentile
- Overactive Thyroid — Typical likelihood, 46th percentile
- Insulin Resistance — Typical, 43th percentile
- ADRA2A (Blood Sugar) — Typical activity, 42th percentile
- Underactive Thyroid — Typical likelihood, 34th percentile
- Uric Acid — Typical levels, 16th percentile
- Type 1 Diabetes — Typical likelihood, 15th percentile
- Adiponectin — Typical levels
- Ghrelin — Typical levels
- Leptin — Typical levels
- LEPR (Weight/Leptin Resistance) — Typical activity
- UCP2 (Weight) — Typical activity
- UCP3 (Weight) — Typical activity
- ADRB3 (Weight) — Typical activity
- CD36 (Fat Preference/Weight) — Typical activity
- CLOCK (Sleep & Weight) — Typical activity
- TFAP2B (Weight/Diet) — Typical activity
- PPARG (Metabolism) — Typical activity
- APOA2 (Weight, Blood Lipids) — Typical activity
- ADIPOQ (Weight/ Blood Sugar) — Typical genetics
- MC3R (Weight) — Typical activity
- PER2 (Dieting) — Typical genetics
- Fasting Glucose — Typical levels
- HbA1c — Typical levels
- Insulin — Typical levels
- Graves' Disease — Typical likelihood
- TSH — Typical levels
- T3 (Triiodothyronine) — Typical levels
- T4 (Thyroxine) — Typical levels
- Free T4 — Typical levels
- Reverse T3 (rT3) — Typical levels
- Free T3 (fT3) — Typical levels
- Ketone Bodies — Typical levels
- Lactate — Typical levels
- Creatine — Typical levels
- TPO (Thyroid) — Typical
- PPARGC1A (Fitness/Blood Sugar) — Typical activity
- GCKR (Blood Sugar) — Typical activity
- GIPR (Blood Sugar) — Typical activity
- PPARA (Keto Diet) — Typical activity
- Diabetic Retinopathy — Typical likelihood
- CRY2 (Blood Sugar) — Typical genetics
- EPA (Omega-3) — Typical response
- DHA (Omega-3) — Typical response
- TA B L E O F C O N T E N T S — Typical levels
- Celiac Disease — Typical likelihood
- Dairy Sensitivity (Casein) — Typical likelihood
- PA G E 1 2 / 2 5 4 — Typical likelihood
- Minerals — Typical need
- Phenylalanine — Typical need
- FUT2 (Gut/ Vitamin B12) — Typical genetics
- PA G E 1 8 / 2 5 4 — Typical
- PUFA Response — Typical levels
- PA G E 4 7 / 2 5 4 — Typical likelihood
- Vitamin E — Typical need
- Thiamine (Vitamin B1) — Typical need
- Magnesium — Typical need
- Chromium — Typical levels
- PA G E 1 1 8 / 2 5 4 — Typical levels
- PA G E 1 2 9 / 2 5 4 — Typical likelihood
- PA G E 1 3 8 / 2 5 4 — Intermediate activity
- Threonine — Typical need
- Histidine — Typical need
- Lysine — Typical need
- Tryptophan — Typical need
- Aspartic Acid — Typical levels
- Asparagine — Typical levels
- Arginine — Typical need
- Glutamine — Typical levels
- Glycine — Typical need
- Proline — Typical need
- Tyrosine — Typical need
- Glutamate — Typical levels
- Ornithine — Typical need
- Citrulline — Typical levels
- Cysteine — Typical levels
- Sarcosine — Typical levels
- Taurine — Typical need
- Carnitine — Typical need
- Beta-Alanine — Typical need
- Glutathione — Typical function
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.