This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Addictions — Addictions are complex conditions that involve a compulsive need to engage in certain behaviors or consume substances, despite negative consequences. While environmental factors, stress, and life experiences contribute to the development of addictions, genetics also plays a
Personality — We tend to put labels on our personalities and categorize ourselves in a variety of ways. As useful as it might be for some situations, everyone’s personality is unique: a complex combination of genetics, life experiences, and environment.
Mood & Mental Health — Mental health and mood regulation are influenced by a combination of environmental factors and genetics. Recent advances in genetic research have unveiled how specific genes and biomarkers may predispose individuals to various mental health conditions, mood disorders, and
Cannabinoids — How your body interacts with cannabinoids depends significantly on your unique genetic profile. This analysis explores three key areas that influence individual responses: metabolic processing, neurological effects, and impact on appetite regulation.
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Engage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.
Psychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.
Attend a support group meeting related to your condition at least once a week.
Set aside 10-20 minutes each day in a quiet space without distractions to practice meditation.
TA focus on your breath, observing thoughts and sensations without judgment.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
Of the 75 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Risk factors for mania include: Bipolar disorder Family history Stress Drug use Sleep deprivation More likely to genetic Treating mania typically involves a combination of medication, psychotherapy, and lifestyle adjustments.
Mood stabilizers such as lithium, anticonvulsants like valproate or carbamazepine, and atypical antipsychotics are often prescribed to manage manic episodes and prevent their recurrence.
Psychotherapy, particularly cognitive-behavioral therapy (CBT) or psychoeducation, can help individuals recognize triggers, Your risk develop coping strategies, and improve insight into their and condition.
Named only. Marrow gives no dose and does not recommend these.
Other risk factors include dieting, major stressful events, and other mental health conditions.
If you have symptoms, talk to a healthcare professional.
About 1% of people may develop an eating disorder at some point in their life.
Binge eating can be associated with: Psychological issues: Low self-esteem, body dissatisfaction, and significant stress can trigger binge eating.
Biological factors: Genetic mutations may affect hunger and satiety, through alterations in brain chemistry that can predispose individuals to eating disorders.
Social and cultural factors: Dysfunctional family dynamics, professions and activities that focus on appearance and dieting, and traumatic situations such as bullying or abuse can increase the risk of BED.
Chronic or excessive feelings of guilt can be particularly debilitating, leading to a well-documented decline in psychological well-being.
It can manifest in physical symptoms such as insomnia, loss of appetite, or gastrointestinal distress due to the close connection between mental and physical health.
In some cases, persistent guilt may also contribute to the development of mental health conditions such as depression, anxiety disorders, and compulsive behaviors.
Factors that might increase the risk of developing BPD include: Childhood abandonment, neglect, or abuse A family history of BPD or other mental health disorders Brain abnormalities, particularly in regions related to emotion regulation, impulsivity, and aggression Neurochemical imbalances in the brain Genetics There is evidence suggesting that genetics plays a role in BPD development.
Having a close family member, such as a parent or sibling, with the disorder can increase the risk of developing BPD.
Research has indicated that certain genetic variants might be linked to BPD, affecting how the brain regulates emotions and impulsivity.
Named only. Marrow gives no dose and does not recommend these.
People with certain genetic markers may be predisposed to aggressive behaviors or heightened anger responses.
However, genes alone don't dictate behavior.
The following factors also play significant roles in how anger is expressed and managed: Chronic stress A family environment where anger was expressed violently or aggressively Past trauma or abuse.
Risk factors include being female, events that cause fear and/or helplessness, lack of support after trauma, additional stressful events, history of mental health conditions or substance abuse, genetics.
If you have high genetic risk or symptoms, you may want to take action on your modifiable factors to reduce your overall risk.
Post-traumatic stress disorder (PTSD) is a mental health condition that commonly affects war veterans.
Not everything in a genetic report is a warning. These came back protective or better than average.
Factors that might increase the risk of experiencing anhedonia include: Having a mood disorder, like depression or bipolar disorder.
Chronic stress or exposure to traumatic events.
Chronic physical illnesses, such as Parkinson's disease or multiple sclerosis.
Caffeine-Related People drink coffee the main ingredient caffeine can make falling asleep. other mental health A gene called your body.
The ADORA2A gene use a compound you sleepy and protein.
For example, one you respond to variant more than men [R, R, R].
The influence of genetics may vary by cognitive ability [R, R, R].
Several genes appear to have a connection with the development of ASD.
Between 10% and 20% of cases can be linked to genetic disorders, such as mutations in genes like SHANK3 and genetic conditions like: Down syndrome Rett syndrome Fragile X syndrome.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-480077 |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-480077 · © 2026 Marrow Health.
General Addiction · Substance Addiction
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Addictions — Addictions are complex conditions that involve a compulsive need to engage in certain behaviors or consume substances, despite negative consequences. While environmental factors, stress, and life experiences contribute to the development of addictions, genetics also plays a
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Attend a support group meeting related to your condition at least once a week.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.
TA focus on your breath, observing thoughts and sensations without judgment.
Participate in art therapy sessions, which can include activities such as painting, sculpting, or drawing, for 1-2 TA hours per week.
TA guided sessions for beginners or those unfamiliar with the poses.
Use a diffuser to disperse the scent into your room TA for 30-60 minutes at a time, up to 3 times a day.
Practice deep breathing exercises for 10 minutes daily, preferably in a quiet space where you won't be disturbed.
Practice this technique at every meal and with snacks to improve digestion and satiety.
Choose a class led by a certified Iyengar yoga TA instructor to ensure proper guidance and technique adherence.
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
Of the 5 results in this package, these 1 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Key Takeaways: About 50% of the differences in people's chances of developing tobacco addiction may be due to genetics.
Other risk factors include age, parents and peers who use tobacco, other substance use, mental health issues like depression or PTSD.
About 8% of people in the U.S. aged 12 and older have a nicotine dependence.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-A64B38 |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-A64B38 · © 2026 Marrow Health.
Big Five Personality Traits · Feelings · Behaviors
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Personality — We tend to put labels on our personalities and categorize ourselves in a variety of ways. As useful as it might be for some situations, everyone’s personality is unique: a complex combination of genetics, life experiences, and environment.
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Engage in music therapy sessions for at least 30 minutes a day, three times a week.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
Participate in art therapy sessions, which can include activities such as painting, sculpting, or drawing, for 1-2 TA hours per week.
Replace them with natural sugars found in fruits and whole grains.
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Include a variety of protein sources such as meat, fish, eggs, dairy, beans, and nuts in your diet every day, aiming for at least of protein per kilogram of body weight.
Set aside 10-20 minutes each day in a quiet space without distractions to practice meditation.
TA focus on your breath, observing thoughts and sensations without judgment.
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
Of the 10 results in this package, these 4 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Chronic or excessive feelings of guilt can be particularly debilitating, leading to a well-documented decline in psychological well-being.
It can manifest in physical symptoms such as insomnia, loss of appetite, or gastrointestinal distress due to the close connection between mental and physical health.
In some cases, persistent guilt may also contribute to the development of mental health conditions such as depression, anxiety disorders, and compulsive behaviors.
Genetics may explain 22-46% of the differences in the tendency of people to procrastinate [R, R, R, R].
A study found that women with the ‘A’ variant at the TH rs10770141 polymorphism had lower decision-related action control, implying an increased tendency to procrastinate.
However, this variant was unrelated to procrastination in men.
Some amount of risk curious and to also be harmful or controlled.
Research has revealed several genetic variants that influence how we process rewards and seek pleasure.
These genes affect our brain's neurotransmitter systems, particularly dopamine and serotonin pathways: COMT (Val158Met, rs4680): The COMT gene regulates dopamine levels in the brain.
The Val (‘G’) variant of rs4680 leads to faster dopamine breakdown, often resulting in seeking more intense experiences to compensate for lower baseline dopamine levels.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-2981A3 |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-2981A3 · © 2026 Marrow Health.
Mood & Emotions · Stress & Anxiety · Mental Health · Brain Chemicals & Genes
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Mood & Mental Health — Mental health and mood regulation are influenced by a combination of environmental factors and genetics. Recent advances in genetic research have unveiled how specific genes and biomarkers may predispose individuals to various mental health conditions, mood disorders, and
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Engage in weekly 50-minute sessions with a certified therapist trained in interpersonal therapy for a duration of TA 12-16 weeks.
Psychodynamic Schedule and attend weekly sessions with a trained psychodynamic therapist for a minimum duration of 6 months to several years, depending on individual needs and progress.
Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.
Set aside 10-20 minutes each day in a quiet space without distractions to practice meditation.
TA focus on your breath, observing thoughts and sensations without judgment.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.
Use a diffuser to disperse the scent into your room TA for 30-60 minutes at a time, up to 3 times a day.
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
Of the 58 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Risk factors for mania include: Bipolar disorder Family history Stress Drug use Sleep deprivation More likely to genetic Treating mania typically involves a combination of medication, psychotherapy, and lifestyle adjustments.
Mood stabilizers such as lithium, anticonvulsants like valproate or carbamazepine, and atypical antipsychotics are often prescribed to manage manic episodes and prevent their recurrence.
Psychotherapy, particularly cognitive-behavioral therapy (CBT) or psychoeducation, can help individuals recognize triggers, Your risk develop coping strategies, and improve insight into their and condition.
Named only. Marrow gives no dose and does not recommend these.
Other risk factors include dieting, major stressful events, and other mental health conditions.
If you have symptoms, talk to a healthcare professional.
About 1% of people may develop an eating disorder at some point in their life.
Binge eating can be associated with: Psychological issues: Low self-esteem, body dissatisfaction, and significant stress can trigger binge eating.
Biological factors: Genetic mutations may affect hunger and satiety, through alterations in brain chemistry that can predispose individuals to eating disorders.
Social and cultural factors: Dysfunctional family dynamics, professions and activities that focus on appearance and dieting, and traumatic situations such as bullying or abuse can increase the risk of BED.
Chronic or excessive feelings of guilt can be particularly debilitating, leading to a well-documented decline in psychological well-being.
It can manifest in physical symptoms such as insomnia, loss of appetite, or gastrointestinal distress due to the close connection between mental and physical health.
In some cases, persistent guilt may also contribute to the development of mental health conditions such as depression, anxiety disorders, and compulsive behaviors.
Factors that might increase the risk of developing BPD include: Childhood abandonment, neglect, or abuse A family history of BPD or other mental health disorders Brain abnormalities, particularly in regions related to emotion regulation, impulsivity, and aggression Neurochemical imbalances in the brain Genetics There is evidence suggesting that genetics plays a role in BPD development.
Having a close family member, such as a parent or sibling, with the disorder can increase the risk of developing BPD.
Research has indicated that certain genetic variants might be linked to BPD, affecting how the brain regulates emotions and impulsivity.
Named only. Marrow gives no dose and does not recommend these.
People with certain genetic markers may be predisposed to aggressive behaviors or heightened anger responses.
However, genes alone don't dictate behavior.
The following factors also play significant roles in how anger is expressed and managed: Chronic stress A family environment where anger was expressed violently or aggressively Past trauma or abuse.
Risk factors include being female, events that cause fear and/or helplessness, lack of support after trauma, additional stressful events, history of mental health conditions or substance abuse, genetics.
If you have high genetic risk or symptoms, you may want to take action on your modifiable factors to reduce your overall risk.
Post-traumatic stress disorder (PTSD) is a mental health condition that commonly affects war veterans.
Not everything in a genetic report is a warning. These came back protective or better than average.
Factors that might increase the risk of experiencing anhedonia include: Having a mood disorder, like depression or bipolar disorder.
Chronic stress or exposure to traumatic events.
Chronic physical illnesses, such as Parkinson's disease or multiple sclerosis.
Caffeine-Related People drink coffee the main ingredient caffeine can make falling asleep. other mental health A gene called your body.
The ADORA2A gene use a compound you sleepy and protein.
For example, one you respond to variant more than men [R, R, R].
The influence of genetics may vary by cognitive ability [R, R, R].
Several genes appear to have a connection with the development of ASD.
Between 10% and 20% of cases can be linked to genetic disorders, such as mutations in genes like SHANK3 and genetic conditions like: Down syndrome Rett syndrome Fragile X syndrome.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-E4ACDF |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-E4ACDF · © 2026 Marrow Health.
Metabolism · Mental Effects · Effects on Appetite
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Cannabinoids — How your body interacts with cannabinoids depends significantly on your unique genetic profile. This analysis explores three key areas that influence individual responses: metabolic processing, neurological effects, and impact on appetite regulation.
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
Stop any form of cannabis use, including smoking, vaping, edibles, and topical applications.
Attend a support group meeting related to your condition at least once a week.
Check for lead-based paints in older homes and avoid cooking or storing food in uncoated metal containers.
Consume fewer calories than your body needs for maintenance.
Reduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.
Practice applied relaxation by dedicating 15-30 minutes each day to learning and practicing relaxation TA techniques, such as deep breathing, progressive muscle relaxation, or guided imagery.
Participate in art therapy sessions, which can include activities such as painting, sculpting, or drawing, for 1-2 TA hours per week.
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Of the 9 results in this package, these 3 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Certain genetic variants may affect the risk and severity of THC-related psychosis.
Carriers of several risk variants may want to consider avoiding cannabis use.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation improves mood and anxiety.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation increases appetite.
The ‘T’ allele of rs806378 is believed to increase CB1 activity.
This variant has been associated with decreased appetite from cannabinoid use (THC, CBD, or their combination) compared to the ‘CC’ genotype.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation increases appetite.
The most studied SNP in this gene is rs1049353 or 1359G/A.
Its minor ‘T’ allele doesn’t change the CB1 receptor structure but is believed to impair gene expression and receptor activity.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-45953A |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-45953A · © 2026 Marrow Health.