Marrow
Genomics · Genetic Reports · Precision Wellness

Cardiovascular Health Package

Personalized 3-Report Genetic Package
Cardiovascular HealthKidney HealthInflammation & Autoimmunity
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-B5A11F
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-B5A11F
Reports in package
3
Results scored
180 of 194
Need attention
26
Report
Summary Report

The reports inside this package

This one document contains 3 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Cardiovascular Health82 results reported of 88 analytes · 50 recommendations
Kidney Health22 results reported of 23 analytes · 50 recommendations
Inflammation & Autoimmunity80 results reported of 83 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 180 results here, 26 came back worth discussing with a clinician and 8 came back in your favour. Bring this document to your appointment.

What this package looks at

Cardiovascular Health — “Oh, my god! That will give you a heart attack!” said every cliche grandmother ever written. There is a notoriously long list for what “that” is, from high cholesterol to stress to weight. Unfortunately, people have a tendency to not worry about a health issue until it becomes a problem. So,

Kidney Health — The kidneys play a vital role in filtering waste and maintaining fluid and electrolyte balance in the body. Genetic factors can influence your susceptibility to various kidney-related conditions, ranging from chronic diseases to acute kidney injuries.

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Coronary Artery Disease, Artery Hardening, Peripheral Artery Disease, ApoB
relevance
2
Avoid Dioxin

Reduce consumption of animal fats, since dioxins accumulate in fat tissue.

Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
relevance
3
Limit Salt Intake

By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
4
Choose Healthy Fats

Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.

Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Lipoprotein(a)
relevance
5
Reduce Oxalate Intake

Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
6
Walking30 minutes

Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.

Relates to: Coronary Artery Disease, Peripheral Artery Disease, Artery Hardening, ApoB
relevance
7
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
8
Limit Protein Intake

Limit your daily protein intake to per kilogram of your body weight.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD)
relevance
9
Avoid Secondhand Smoke

Avoid Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Coronary Artery Disease, Artery Hardening, ApoB, Homocysteine
relevance
10
Sleep for 7+ Hours

Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.

Relates to: Coronary Artery Disease, Heart Rate Recovery, Artery Hardening, ApoB
relevance
11
Limit Saturated Fat

Reduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.

Relates to: Artery Hardening, Peripheral Artery Disease, Coronary Artery Disease, Lipoprotein(a)
relevance
12
Stair Climbing10 minutes

Aim for at least 10 minutes of continuous stair climbing or multiple shorter sessions that add up to 10 minutes per day.

Relates to: Coronary Artery Disease, Artery Hardening
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Methylfolate
Relates to: Homocysteine, Retinal Vein Occlusion, Coronary Artery Disease, Artery Hardening
relevance
2
Dietary Omega-3 Fatty Acids
Relates to: Heart Failure, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
relevance

Your headline findings

Of the 180 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Varicose VeinsMore likely
More likely to have varicose veins based on 81,137 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: age, being female, overweight, sitting or standing most of the day, pregnancy, and childbirth.

If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.

Normal, healthy veins have many valves that keep the blood flowing in the right direction.

What you can do

  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
  • Apples
    Incorporate at least one whole apple into your daily diet, either as a snack or part of your meals, ensuring to eat them consistently every day for an ongoing period to derive potential health benefits.

Ask your clinician about

  • Pycnogenol

Named only. Marrow gives no dose and does not recommend these.

From your Cardiovascular Health report
Blood SpotsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
From your Cardiovascular Health report
PalpitationsMore likely
More likely to have palpitations based on 1,209,944 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Key Takeaways: While no heritability percentage exists yet for this condition, genes involved may influence various heart functions.

Other risk factors include stress, anxiety, pregnancy, age, stimulants, overactive thyroid, and heart problems.

Experiencing palpitations are not uncommon, particularly because they can result from causes unrelated to heart conditions, like anxiety.

From your Cardiovascular Health report
Low Blood PressureMore likely
More likely to have low blood pressure based on 54,555 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Key Takeaways: Genetics may play a role by influencing nervous system function, kidney function, and hormone activity.

Other risk factors include certain medications and health conditions.

It is estimated that up to 25% of adults may have low blood pressure.

What you can do

  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
  • Hazelnuts
    Incorporate a handful of hazelnuts (about or) into your diet daily.
From your Cardiovascular Health report
Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Kidney StonesMore likely
More likey to have kidney stones based on 816,639 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Key Takeaways: About 50% of differences in people's chances of developing kidney stones may be due to genetics.

Risk factors include dehydration, excess animal protein, salt, or sugar, obesity, IBD, UTIs, medications, excess vitamin C.

About 11% of American men and 7% of women have kidney stones.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Renal ColicMore likely
More likely to have a renal colic based on 437,591 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Renal colic can be who have a history stones, such as underlying their formation. nonsteroidal necessary.

Hydration is cases, medical stone removal may large to pass or complications.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
A further 18 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Cardiovascular Health report
Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Risk factors include being under age 30, European ancestry, and smoking.

IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.

IBD only affects about 3 in 1000 people worldwide.

From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Inflammation & Autoimmunity report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (18)
  • Artery Hardening — More likely, 95th percentile
  • Pancreas Inflammation — More likely, 95th percentile
  • Acute Kidney Injury — More likely, 93th percentile
  • Retinal Vein Occlusion — More likely, 90th percentile
  • Urethra Inflammation — More likely, 88th percentile
  • Eye Inflammation — More likely, 84th percentile
  • Coronary Artery Disease — More likely, 67th percentile
  • Crohn’s Disease — More likely, 66th percentile
  • Psoriasis — More likely, 65th percentile
  • Heart Failure — More likely
  • Myocarditis — More likely
  • Subarachnoid Hemorrhage — More likely
  • Brain Hemorrhage — More likely
  • Peripheral Artery Disease — More likely
  • Polycystic Kidney Disease — More likely
  • Kidney Failure (ESRD) — More likely
  • Nephritis — More likely
  • Diabetic Nephropathy — More likely
Running above the typical range  (23)
  • ApoB — Higher levels, 99th percentile
  • ADRB1 (Cardiovascular) — Higher activity, 92th percentile
  • IRS1 (Metabolic Health) — Higher activity, 85th percentile
  • Lipoprotein(a) — Higher levels, 81th percentile
  • HLA (Inflammation) — Higher activity, 80th percentile
  • Heart Rate Variability — Higher
  • PCSK9 (Cholesterol) — Higher activity
  • CELSR2-PSRC1-SORT1 (Cardiovascular) — Higher activity
  • AGT (Cardiovascular & Fitness) — Higher activity
  • GCH1 (Cardiovascular) — Higher activity
  • LIPC (Cardiovascular) — Higher activity
  • TMAO — Higher levels
  • Homocysteine — Higher levels
  • Platelet Aggregation — Higher
  • Albumin — Higher levels
  • GRHPR (Oxalate & Kidneys) — Higher activity
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
Running below the typical range  (15)
  • Heart Rate Recovery — Slower
  • CPS1 (Cardiovascular, Kidney Health) — Lower activity
  • DOCK7 (Blood Lipids) — Lower activity
  • FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
  • CETP (Cholesterol/ Longevity) — Lower activity
  • ACE (Fitness/ Cardiovascular) — Lower activity
  • MLXIPL (Triglycerides, Cardiovascular) — Lower activity
  • SOAT1 (Cholesterol/ Cognition) — Lower activity
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour  (5)
  • Optic Nerve Inflammation — Less likely, 19th percentile
  • Mitral Valve Prolapse — Less likely
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
In line with most people  (108)
  • Peripheral Vascular Disease — Typical likelihood, 98th percentile
  • Chronic Venous Insufficiency — Typical likelihood, 85th percentile
  • Heart Arrhythmia — Typical likelihood, 67th percentile
  • POTS — Typical likelihood, 65th percentile
  • VLDL Cholesterol — Typical levels, 65th percentile
  • Stroke — Typical likelihood, 63th percentile
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Venous Thromboembolism — Typical likelihood, 61th percentile
  • Total Cholesterol — Typical levels, 61th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Blood Clotting — Typical likelihood, 52th percentile
  • High Blood Pressure — Typical likelihood, 51th percentile
  • LDL Particle Number (LDL-P) — Typical, 47th percentile
  • High Cholesterol — Typical likelihood, 46th percentile
  • LDL Cholesterol — Typical levels, 44th percentile
  • Kidney Problems — Typical likelihood, 44th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Atrial Fibrillation — Typical likelihood, 39th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Cold Hands and Feet (Raynaud's) — Typical likelihood, 31th percentile
  • Eczema — Typical likelihood, 29th percentile
  • IL-6 — Typical levels, 20th percentile
  • Uric Acid — Typical levels, 16th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Heart Attack — Typical likelihood
  • Rheumatic Heart Disease — Typical likelihood
  • Aortic Stenosis — Typical likelihood
  • Dilated Cardiomyopathy — Typical likelihood
  • Hypertrophic Cardiomyopathy — Typical likelihood
  • Aortic Valve Calcification — Typical likelihood
  • Aortic Aneurysm — Typical likelihood
  • Brain Aneurysm — Typical likelihood
  • Cerebral Small Vessel Disease — Typical likelihood
  • Brain Ischemia — Typical likelihood
  • Vasculitis — Typical likelihood
  • Deep Vein Thrombosis — Typical likelihood
  • Heart Rate — Typical
  • Tachycardia — Typical likelihood
  • Bradycardia — Typical likelihood
  • Salt Sensitivity — Typical
  • Pulmonary Hypertension — Typical likelihood
  • APOC3 (Blood Lipids/ Longevity) — Typical activity
  • NOS3 (Cardiovascular) — Typical activity
  • HMGCR (Cholesterol) — Typical activity
  • APOA2 (Weight, Blood Lipids) — Typical activity
  • APOB Gene (Cardiovascular) — Typical activity
  • ABCA1 (Cholesterol) — Typical genetics
  • LPA (Blood Lipids & Heart Health) — Typical activity
  • LDLR (Cholesterol, Cardiovascular) — Typical activity
  • LDL Particle Size — Typical
  • Lp-PLA2 — Typical levels
  • Platelets — Typical levels
  • Response to Ezetimibe — Typical
  • Response to Statins (Functional) — Typical response
  • IgA Nephropathy — Typical likelihood
  • Contrast-Induced Nephropathy — Typical likelihood
  • eGFR — Typical levels
  • Creatinine — Typical levels
  • Blood Urea Nitrogen (BUN) — Typical levels
  • Sodium — Typical levels
  • Total Protein — Typical levels
  • Cystatin C — Typical levels
  • Potassium — Typical need
  • Chloride — Typical levels
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Psoriatic Arthritis — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-B5A11F
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-B5A11F · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Cardiovascular Health

Personalized Genetic Report
Heart HealthBrain VesselsVeins & Other VesselsHeart RateBlood PressureHeart Health GenesCholesterol & Lab Markers
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-8B1A34
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-8B1A34
Panel
Cardiovascular Health
Results scored
82 of 88
Need attention
12
Report
Summary Report

What this report covers

Heart Health · Brain Vessels · Veins & Other Vessels · Heart Rate · Blood Pressure · Heart Health Genes · Cholesterol & Lab Markers

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 82 results here, 12 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.

What this package looks at

Cardiovascular Health — “Oh, my god! That will give you a heart attack!” said every cliche grandmother ever written. There is a notoriously long list for what “that” is, from high cholesterol to stress to weight. Unfortunately, people have a tendency to not worry about a health issue until it becomes a problem. So,

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Coronary Artery Disease, Artery Hardening, Peripheral Artery Disease, ApoB
relevance
2
Choose Healthy Fats

Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.

Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Lipoprotein(a)
relevance
3
Walking30 minutes

Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.

Relates to: Coronary Artery Disease, Peripheral Artery Disease, Artery Hardening, ApoB
relevance
4
Avoid Secondhand Smoke

Avoid Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Coronary Artery Disease, Artery Hardening, ApoB, Homocysteine
relevance
5
Sleep for 7+ Hours

Ensure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.

Relates to: Coronary Artery Disease, Heart Rate Recovery, Artery Hardening, ApoB
relevance
6
Limit Saturated Fat

Reduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.

Relates to: Artery Hardening, Peripheral Artery Disease, Coronary Artery Disease, Lipoprotein(a)
relevance
7
Stair Climbing10 minutes

Aim for at least 10 minutes of continuous stair climbing or multiple shorter sessions that add up to 10 minutes per day.

Relates to: Coronary Artery Disease, Artery Hardening
relevance
8
Eat Fiber-Rich Foods

grams per day, spread out over all meals.

Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
relevance
9
DASH Diet

This diet should be followed daily to manage blood pressure effectively.

Relates to: Coronary Artery Disease, Heart Failure, Artery Hardening, Peripheral Artery Disease
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Methylfolate
Relates to: Homocysteine, Retinal Vein Occlusion, Coronary Artery Disease, Artery Hardening
relevance
2
Dietary Omega-3 Fatty Acids
Relates to: Heart Failure, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
relevance
3
Omega-3 (Fish Oil)
Relates to: Artery Hardening, Coronary Artery Disease, Homocysteine, Heart Failure
relevance
4
Genistein
Relates to: Artery Hardening, Homocysteine, Coronary Artery Disease, Lipoprotein(a)
relevance
5
Pycnogenol
Relates to: Varicose Veins, Coronary Artery Disease, Artery Hardening
relevance

Your headline findings

Of the 82 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Varicose VeinsMore likely
More likely to have varicose veins based on 81,137 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: age, being female, overweight, sitting or standing most of the day, pregnancy, and childbirth.

If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.

Normal, healthy veins have many valves that keep the blood flowing in the right direction.

What you can do

  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
  • Apples
    Incorporate at least one whole apple into your daily diet, either as a snack or part of your meals, ensuring to eat them consistently every day for an ongoing period to derive potential health benefits.

Ask your clinician about

  • Pycnogenol

Named only. Marrow gives no dose and does not recommend these.

From your Cardiovascular Health report
Blood SpotsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
From your Cardiovascular Health report
PalpitationsMore likely
More likely to have palpitations based on 1,209,944 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Key Takeaways: While no heritability percentage exists yet for this condition, genes involved may influence various heart functions.

Other risk factors include stress, anxiety, pregnancy, age, stimulants, overactive thyroid, and heart problems.

Experiencing palpitations are not uncommon, particularly because they can result from causes unrelated to heart conditions, like anxiety.

From your Cardiovascular Health report
Low Blood PressureMore likely
More likely to have low blood pressure based on 54,555 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Key Takeaways: Genetics may play a role by influencing nervous system function, kidney function, and hormone activity.

Other risk factors include certain medications and health conditions.

It is estimated that up to 25% of adults may have low blood pressure.

What you can do

  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
  • Hazelnuts
    Incorporate a handful of hazelnuts (about or) into your diet daily.
From your Cardiovascular Health report
Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.

Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.

The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Choose Healthy Fats
    Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.
  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
From your Cardiovascular Health report
Retinal Vein OcclusionMore likely
Higher predisposition than 90% of people
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

Retinal Vein Treatment for underlying risk from the blockage. injections of vision, laser reduce inflammation.

Ask your clinician about

  • Methylfolate
  • Dietary Omega-3 Fatty Acids
  • Genistein

Named only. Marrow gives no dose and does not recommend these.

From your Cardiovascular Health report
Coronary Artery DiseaseMore likely
More likely to have coronary artery disease based on 1,049,366 genetic variants we looked at
Your risk is greater than 67% of the population and lower than 33% of the population.

What this actually is

Key Takeaways: Over 18 million people have heart disease in the U.S.

A third of deaths from heart disease are preventable.

Other risk factors include excess weight, stress, sedentary lifestyle, smoking, and more.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Choose Healthy Fats
    Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.
  • Walking 30 minutes
    Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
From your Cardiovascular Health report
Heart FailureMore likely
More likely to have heart failure based on 35,698 genetic variants we looked at

What this actually is

Key risk factors: high blood pressure, diabetes, coronary artery disease, arrhythmias, and infections.

Heart failure affects about 26 million people worldwide, with about 6 million of those in the U.S.

If your genetic risk is high, you may lower your overall risk by taking action on those risk factors that you can change.

What you can do

  • DASH Diet
    This diet should be followed daily to manage blood pressure effectively.
  • Hydroxytyrosol And Punicalagin
    per day, and for punicalagin, it is about per day.

Ask your clinician about

  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Cardiovascular Health report
A further 4 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Cardiovascular Health report
Mitral Valve ProlapseLess likely
Less likely to have mitral valve prolapse based on 1,668 genetic variants we looked at

What this actually is

Risk factors for mitral valve prolapse include: Being female Connective tissue disorders, like Marfan syndrome or Ehlers-Danlos syndrome Scoliosis or other skeletal problems MVP can sometimes run in families, suggesting a genetic component to the condition.

It is also associated with genetic connective tissue disorders like Marfan syndrome, which is caused by mutations in the FBN1 gene.

Most people with MVP don't need treatment unless the condition is severe or causing significant symptoms.

From your Cardiovascular Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (4)
  • Myocarditis — More likely
  • Subarachnoid Hemorrhage — More likely
  • Brain Hemorrhage — More likely
  • Peripheral Artery Disease — More likely
Running above the typical range  (13)
  • ApoB — Higher levels, 99th percentile
  • ADRB1 (Cardiovascular) — Higher activity, 92th percentile
  • IRS1 (Metabolic Health) — Higher activity, 85th percentile
  • Lipoprotein(a) — Higher levels, 81th percentile
  • Heart Rate Variability — Higher
  • PCSK9 (Cholesterol) — Higher activity
  • CELSR2-PSRC1-SORT1 (Cardiovascular) — Higher activity
  • AGT (Cardiovascular & Fitness) — Higher activity
  • GCH1 (Cardiovascular) — Higher activity
  • LIPC (Cardiovascular) — Higher activity
  • TMAO — Higher levels
  • Homocysteine — Higher levels
  • Platelet Aggregation — Higher
Running below the typical range  (8)
  • Heart Rate Recovery — Slower
  • CPS1 (Cardiovascular, Kidney Health) — Lower activity
  • DOCK7 (Blood Lipids) — Lower activity
  • FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
  • CETP (Cholesterol/ Longevity) — Lower activity
  • ACE (Fitness/ Cardiovascular) — Lower activity
  • MLXIPL (Triglycerides, Cardiovascular) — Lower activity
  • SOAT1 (Cholesterol/ Cognition) — Lower activity
In line with most people  (47)
  • Peripheral Vascular Disease — Typical likelihood, 98th percentile
  • Chronic Venous Insufficiency — Typical likelihood, 85th percentile
  • Heart Arrhythmia — Typical likelihood, 67th percentile
  • POTS — Typical likelihood, 65th percentile
  • VLDL Cholesterol — Typical levels, 65th percentile
  • Stroke — Typical likelihood, 63th percentile
  • Venous Thromboembolism — Typical likelihood, 61th percentile
  • Total Cholesterol — Typical levels, 61th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Blood Clotting — Typical likelihood, 52th percentile
  • High Blood Pressure — Typical likelihood, 51th percentile
  • LDL Particle Number (LDL-P) — Typical, 47th percentile
  • High Cholesterol — Typical likelihood, 46th percentile
  • LDL Cholesterol — Typical levels, 44th percentile
  • Atrial Fibrillation — Typical likelihood, 39th percentile
  • Cold Hands and Feet (Raynaud's) — Typical likelihood, 31th percentile
  • Heart Attack — Typical likelihood
  • Rheumatic Heart Disease — Typical likelihood
  • Aortic Stenosis — Typical likelihood
  • Dilated Cardiomyopathy — Typical likelihood
  • Hypertrophic Cardiomyopathy — Typical likelihood
  • Aortic Valve Calcification — Typical likelihood
  • Aortic Aneurysm — Typical likelihood
  • Brain Aneurysm — Typical likelihood
  • Cerebral Small Vessel Disease — Typical likelihood
  • Brain Ischemia — Typical likelihood
  • Vasculitis — Typical likelihood
  • Deep Vein Thrombosis — Typical likelihood
  • Heart Rate — Typical
  • Tachycardia — Typical likelihood
  • Bradycardia — Typical likelihood
  • Salt Sensitivity — Typical
  • Pulmonary Hypertension — Typical likelihood
  • APOC3 (Blood Lipids/ Longevity) — Typical activity
  • NOS3 (Cardiovascular) — Typical activity
  • HMGCR (Cholesterol) — Typical activity
  • APOA2 (Weight, Blood Lipids) — Typical activity
  • APOB Gene (Cardiovascular) — Typical activity
  • ABCA1 (Cholesterol) — Typical genetics
  • LPA (Blood Lipids & Heart Health) — Typical activity
  • LDLR (Cholesterol, Cardiovascular) — Typical activity
  • LDL Particle Size — Typical
  • Lp-PLA2 — Typical levels
  • Platelets — Typical levels
  • Response to Ezetimibe — Typical
  • Response to Statins (Functional) — Typical response

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-8B1A34
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-8B1A34 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Kidney Health

Personalized Genetic Report
Chronic Kidney ProblemsAcute Kidney ProblemsKidney Health MarkersKidney Health Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-730ACD
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-730ACD
Panel
Kidney Health
Results scored
22 of 23
Need attention
7
Report
Summary Report

What this report covers

Chronic Kidney Problems · Acute Kidney Problems · Kidney Health Markers · Kidney Health Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 22 results here, 7 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Kidney Health — The kidneys play a vital role in filtering waste and maintaining fluid and electrolyte balance in the body. Genetic factors can influence your susceptibility to various kidney-related conditions, ranging from chronic diseases to acute kidney injuries.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Dioxin

Reduce consumption of animal fats, since dioxins accumulate in fat tissue.

Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
relevance
2
Limit Salt Intake

By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
3
Reduce Oxalate Intake

Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
4
Limit Protein Intake

Limit your daily protein intake to per kilogram of your body weight.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD)
relevance
5
Avoid Sugary Foods & Drinks

Aim to do this daily for ongoing health benefits.

Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
relevance
6
Avoid Secondhand Smoke

Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Kidney Stones
relevance
7
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Polycystic Kidney Disease
relevance
8
Pterostilbene

NRPT was safe and well-tolerated, with minor side effects reported in some cases.

Relates to: Acute Kidney Injury
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Omega-3 (Fish Oil)
Relates to: Kidney Stones, Kidney Failure (ESRD), Polycystic Kidney Disease
relevance
2
Hibiscus
Relates to: Kidney Stones
relevance
3
Avoid Vitamin C Supplements
Relates to: Kidney Stones, Polycystic Kidney Disease
relevance
4
N-acetylcysteine (NAC)
Relates to: Kidney Failure (ESRD), Acute Kidney Injury, Nephritis
relevance
5
Magnesium Sulfate
Relates to: Acute Kidney Injury
relevance
6
Potassium Magnesium Citrate
Relates to: Kidney Stones
relevance

Your headline findings

Of the 22 results in this package, these 7 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Kidney StonesMore likely
More likey to have kidney stones based on 816,639 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Key Takeaways: About 50% of differences in people's chances of developing kidney stones may be due to genetics.

Risk factors include dehydration, excess animal protein, salt, or sugar, obesity, IBD, UTIs, medications, excess vitamin C.

About 11% of American men and 7% of women have kidney stones.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Renal ColicMore likely
More likely to have a renal colic based on 437,591 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Renal colic can be who have a history stones, such as underlying their formation. nonsteroidal necessary.

Hydration is cases, medical stone removal may large to pass or complications.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Acute Kidney InjuryMore likely
Higher predisposition than 93% of people
Your result sits higher than 93% of the population.

What you can do

  • Pterostilbene
    NRPT was safe and well-tolerated, with minor side effects reported in some cases.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Ask your clinician about

  • Magnesium Sulfate

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Polycystic Kidney DiseaseMore likely
More likely to have polycystic kidney disease managing symptoms and slowing the based on 30,032 genetic variants we looked at

What you can do

  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Ask your clinician about

  • Omega-3 (Fish Oil)
  • Avoid Vitamin C Supplements

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Kidney Failure (ESRD)More likely
Higher predisposition than average

What this actually is

Kidney Failure Conditions that may Diabetes High blood Polycystic Kidney stones Urinary tract Managing these progression of to control blood symptoms.

Dialysis, may be necessary to the blood in cases instances, a kidney solution.

Alongside medical maintaining a staying hydrated, consumption can overall health. essential to adjust outcomes.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.

Ask your clinician about

  • N-acetylcysteine (NAC)

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
NephritisMore likely
More likely to have nephritis based on 626,851 genetic variants we looked at

What this actually is

Symptoms of nephritis may vary depending on the type and severity of the condition but can include hematuria (blood in the urine), proteinuria (protein in the urine), high blood pressure, and edema (swelling of the body, especially in the legs, ankles, or face).

can arise due to various causes including autoimmune disorders, infections, toxins, or as a reaction to certain medications.

Prompt diagnosis and treatment are crucial in managing the condition to prevent further kidney damage and associated health complications.

What you can do

  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.

Ask your clinician about

  • N-acetylcysteine (NAC)

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Diabetic NephropathyMore likely
More likely to have diabetic nephropathy based on 28,985 genetic variants we looked at

What this actually is

Factors linked to an increased risk of diabetic nephropathy include: Poorly controlled blood sugar levels High blood pressure Long duration of diabetes Smoking Obesity Family history of kidney disease High cholesterol levels Managing diabetic nephropathy involves controlling blood sugar and blood pressure, alongside lifestyle changes.

Common treatments include: Medications: ACE inhibitors or ARBs to control blood pressure, blood sugar-lowering drugs, and statins for cholesterol management.

Dietary changes: Low-protein and low-sodium diets to reduce kidney strain.

From your Kidney Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (2)
  • Albumin — Higher levels
  • GRHPR (Oxalate & Kidneys) — Higher activity
Running below the typical range  (1)
  • CPS1 (Cardiovascular, Kidney Health) — Lower activity
In line with most people  (12)
  • Kidney Problems — Typical likelihood, 44th percentile
  • Uric Acid — Typical levels, 16th percentile
  • IgA Nephropathy — Typical likelihood
  • Contrast-Induced Nephropathy — Typical likelihood
  • eGFR — Typical levels
  • Creatinine — Typical levels
  • Blood Urea Nitrogen (BUN) — Typical levels
  • Sodium — Typical levels
  • Total Protein — Typical levels
  • Cystatin C — Typical levels
  • Potassium — Typical need
  • Chloride — Typical levels

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-730ACD
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-730ACD · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Inflammation & Autoimmunity

Personalized Genetic Report
Inflammatory Gut ConditionsOther Inflammatory ConditionsAutoimmune Joint ConditionsAutoimmune Skin ConditionsOther Autoimmune ConditionsInflammation MarkersHLA GenesOther Inflammation Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-0FCD26
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-0FCD26
Panel
Inflammation & Autoimmunity
Results scored
80 of 83
Need attention
9
Report
Summary Report

What this report covers

Inflammatory Gut Conditions · Other Inflammatory Conditions · Autoimmune Joint Conditions · Autoimmune Skin Conditions · Other Autoimmune Conditions · Inflammation Markers · HLA Genes · Other Inflammation Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 80 results here, 9 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
2
Yoga30 minutes

Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Relates to: Crohn’s Disease, Pancreas Inflammation, Eye Inflammation, Psoriasis
relevance
3
Dietary Antioxidants

Avoid Cannabis Stop any form of cannabis use, including smoking, vaping, edibles, and topical applications.

Relates to: Pancreas Inflammation, Psoriasis, Myocarditis, Crohn’s Disease
relevance
4
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Pancreas Inflammation, Eye Inflammation
relevance
5
Antioxidant Supplements
Relates to: Pancreas Inflammation
relevance
6
Pancreatic Enzymes

based on the degree of pancreatic insufficiency and the fat content of the meal.

Relates to: Pancreas Inflammation, Psoriasis
relevance
7
Avoid Refined Sugar

Replace them with natural sugars found in fruits and whole grains.

Relates to: Crohn’s Disease, Myocarditis, Pancreas Inflammation
relevance
8
Autoimmune Protocol (AIP) Diet

Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Relates to: Crohn’s Disease, Eye Inflammation, Thyroid Inflammation
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Crohn’s Disease, Thyroid Inflammation, HLA-DOB (Inflammation), Psoriasis
relevance
2
Omega-3 (Fish Oil)
Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
relevance
3
Dietary Omega-3 Fatty Acids
Relates to: Crohn’s Disease, Myocarditis, Nephritis, Pancreas Inflammation
relevance
4
Probiotics
Relates to: Pancreas Inflammation, SH2B3 (Autoimmunity), Crohn’s Disease, NLRP3 (Gut Inflammation)
relevance
5
Curcumin
Relates to: NLRP3 (Gut Inflammation), Crohn’s Disease, Psoriasis, Eye Inflammation
relevance
6
Boswellia
Relates to: Crohn’s Disease
relevance

Your headline findings

Of the 80 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Pancreas InflammationMore likely
More likely to get pancreas inflammation based on 1,669 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

The pancreas is an organ located behind the stomach that releases crucial enzymes for carbs and fats digestion.

Pancreatitis is inflammation of the pancreas, which can be acute or chronic.

Potential risk factors for pancreatitis include [R, R, R]: Alcohol Cigarette smoking Obesity High blood lipids Certain medications Genetics Genetically predicted higher fasting insulin may be associated with acute and chronic pancreas inflammation.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Probiotics
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Urethra InflammationMore likely
More likely to have non-specific urethritis based infections
Your risk is greater than 88% of the population and lower than 12% of the population.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Eye InflammationMore likely
More likely to have uveitis based on 3,409 genetic variants we looked at
Your risk is greater than 84% of the population and lower than 16% of the population.

What this actually is

The management of uveitis involves addressing both the inflammation and the underlying cause if identified.

Typical treatments include corticosteroids to reduce the inflammation and drugs that manage the immune system's response.

Careful monitoring by an ophthalmologist is critical to prevent complications such as glaucoma, cataracts, and macular edema, all of which could lead to loss of vision.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Crohn’s DiseaseMore likely
More likely to get Crohn's disease based on 1,031,499 genetic variants we looked at
Your risk is greater than 66% of the population and lower than 34% of the population.

What this actually is

Aside from gastrointestinal symptoms, Crohn's Disease can also have systemic effects on the body, leading to issues such as anemia, skin rashes, arthritis, and eye inflammation.

The cause of Crohn's Disease is not fully understood, but it involves an abnormal immune response to the microorganisms in the intestine, in genetically susceptible individuals.

There's no known cure for Crohn's Disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission and healing of inflammation.

What you can do

  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
PsoriasisMore likely
More likely to have psoriasis based on 1,049,035 genetic variants we looked at
Your risk is greater than 65% of the population and lower than 35% of the population.

What this actually is

triggers include: infections, weather, skin injuries, stress, cigarette smoke, alcohol abuse, steroid withdrawal.

About 2% of Americans have psoriasis, mostly appearing in younger and older adults.

Even though the condition is rare, people with high genetic risk should understand and be wary of potential triggers.

What you can do

  • Pancreatic Enzymes
    based on the degree of pancreatic insufficiency and the fat content of the meal.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
MyocarditisMore likely
Higher predisposition than average

What this actually is

Myocarditis can be Viral parvovirus, and Bacterial Parasitic cruzi and Autoimmune Exposure to certain Allergic There is some myocarditis, associated with might influence how and other triggers Preventing avoiding avoiding toxic identify early symptoms of a palpitations.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Potassium
  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
A further 1 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Risk factors include being under age 30, European ancestry, and smoking.

IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.

IBD only affects about 3 in 1000 people worldwide.

From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Inflammation & Autoimmunity report
Optic Nerve InflammationLess likely
Lower predisposition than 81% of people
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Optic Nerve The causes of optic to autoimmune neuromyelitis indication of MS in infections can Recovery from optic weeks in most few months, some permanent vision corticosteroids to recovery of vision, among individuals.

From your Inflammation & Autoimmunity report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (1)
  • Nephritis — More likely
Running above the typical range  (8)
  • HLA (Inflammation) — Higher activity, 80th percentile
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
Running below the typical range  (7)
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour  (3)
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
In line with most people  (50)
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Eczema — Typical likelihood, 29th percentile
  • IL-6 — Typical levels, 20th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Psoriatic Arthritis — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • IgA Nephropathy — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-0FCD26
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-0FCD26 · © 2026 Marrow Health.