Marrow
Genomics · Genetic Reports · Precision Wellness

Inflammation & Autoimmunity Package

Personalized 4-Report Genetic Package
Inflammation & AutoimmunityImmunity & InfectionsHLA DNA AutoimmunityHistamine
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-81D64E
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-81D64E
Reports in package
4
Results scored
151 of 179
Need attention
23
Report
Summary Report

The reports inside this package

This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Inflammation & Autoimmunity80 results reported of 83 analytes · 50 recommendations
Immunity & Infections77 results reported of 77 analytes · 50 recommendations
HLA DNA Autoimmunity7 results reported of 7 analytes · 12 recommendations
Histamine12 results reported of 12 analytes · 16 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 151 results here, 23 came back worth discussing with a clinician and 12 came back in your favour. Bring this document to your appointment.

What this package looks at

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

Immunity & Infections — The immune system is the body’s primary defense against infections, working tirelessly to ward off harmful viruses, bacteria, and other pathogens. However, genetic factors can influence how effectively your immune system responds to various infections and how prone you may be

HLA DNA Autoimmunity — Your immune system's ability to distinguish between "self" and "non-self" is largely influenced by your HLA (Human Leukocyte Antigen) genes. These genes act like your body's security system, playing a crucial role in how your immune system recognizes and responds to various threats.

Histamine — Histamine is a crucial molecule that plays multiple roles in your body, from immune responses to neurotransmitter function and digestion. This analysis explores genetic variations that influence every aspect of histamine metabolism -from production and storage to breakdown and

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Safer Sex Practices

Reduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners.

Relates to: Genital Herpes, Flu
relevance
2
Probiotics
Relates to: C. difficile Infection, Gastrointestinal Infection, Yeast Infection, Flu
relevance
3
Regular Hand Washing

Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.

Relates to: Flu, C. difficile Infection, Gastrointestinal Infection, Eye Stye
relevance
4
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
5
Drink at Least 8 Glasses of Water a Day

Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.

Relates to: C. difficile Infection, Gastrointestinal Infection, Urinary Tract Infections, Acute Bronchitis
relevance
6
Good Hygiene Practices

Wash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home.

Relates to: Flu, C. difficile Infection
relevance
7
Airway Muscle Training30 minutes

Perform airway muscle training exercises daily for at least 30 minutes.

Relates to: Long COVID
relevance
8
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Long COVID
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Zinc
Relates to: Gastrointestinal Infection, C. difficile Infection, Flu, Shigella Infection
relevance
2
Good Oral Hygiene
Relates to: Yeast Infection, Flu, Gastrointestinal Infection, Pneumococcal Disease
relevance
3
Prebiotics
Relates to: Gut Microbiome Diversity, C. difficile Infection
relevance
4
Maintain Optimal Vitamin D Levels
Relates to: Crohn’s Disease, Thyroid Inflammation, Urinary Tract Infections, HLA-DOB (Inflammation)
relevance
5
Omega-3 (Fish Oil)
Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
relevance
6
Dietary Omega-3 Fatty Acids
Relates to: Crohn’s Disease, Myocarditis, Nephritis, Pancreas Inflammation
relevance

Your headline findings

Of the 151 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc
  • Good Oral Hygiene

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report & Immunity & Infections
FluMore likely
More likely to get the flu based on 8,860 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Flu (influenza) is a respiratory infection of the nose, throat and lungs, transferred via droplets that are either inhaled or picked up from surfaces.

Studies show that genetic factors can play a significant role in the risk of developing severe flu symptoms.

What you can do

  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
  • Good Hygiene Practices
    Wash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home.
  • Probiotics
From your Immunity & Infections report
Yeast InfectionMore likely
More likely to have yeast infections based on 104,352 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Candida albicans is a fungus that normally lives in and on the body.

If its environment changes and promotes its growth, Candida can multiply and lead to an infection.

This is called a yeast infection or candidiasis.

What you can do

  • Probiotics
  • Topical Aloe Vera
    Avoid using scented products like douches, sprays, or powders in the genital area.

Ask your clinician about

  • Good Oral Hygiene

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Gastrointestinal InfectionMore likely
More likely to get a GI infection based on 49,910 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Gastrointestinal (GI) infections are diseases of the digestive system.

They are caused by the invasion of microbes that do not usually live there.

The main sources of infection include: Person-to-person contact Consumption of contaminated food (e.g., undercooked or poorly stored meat, raw milk) Consumption of contaminated water (e.g., river or swimming pool water) Contact with contaminated objects (e.g., soil, work tools) Contact with animals or their feces (e.g., contact with farm animals and pets, visiting petting zoos) Risk factors for GI infections include [R, R, R, R, R, R].

What you can do

  • Probiotics
  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Eye StyeMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population ng treatments can help alleviate symptoms and lower than 1% of the population.

What this actually is

Styes can develop eyelashes become factors include: Poor hygiene: transfer Makeup use: remove makeup blockages.

Eye irritation: hygiene or Chronic are more prone Most styes heal on However, the and speed up Warm affected eyelid help the stye Massage: Gently may help applying warm Keep it clean: keeping it Avoid makeup makeup or further relievers can Preventive measures removing makeup the eyes with significantly eye infections.

What you can do

  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
From your Immunity & Infections report
Genital HerpesMore likely
More likely to get genital herpes based on 284,981 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Genital herpes is a common sexually transmitted infection (STI), usually caused by the herpes simplex virus type 2 (HSV-2).

Genetics may also affect susceptibility to genital herpes.

Involved genes may play a role in the immune response, cell life cycle, and more.

What you can do

  • Safer Sex Practices
    Reduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners.
  • Topical Aloe Vera
    Avoid using scented products like douches, sprays, or powders in the genital area.
From your Immunity & Infections report
Low NeutrophilsMore likely
More likely to have neutropenia based on 1,674 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Neutropenia is typically diagnosed through a complete blood count test, which evaluates the levels of various types of cells in the blood.

If neutropenia is detected, further tests may be required to determine its cause: Bone marrow biopsy: To examine the health and status of the bone marrow.

Blood tests: To check for infections, vitamin deficiencies (such as B12 and folate), and autoimmune disorders.

What you can do

  • Avoid Crowds
    Minimize your time in crowded places by scheduling your errands during off-peak hours, avoiding public events known to draw large crowds, and choosing less crowded routes or modes of transportation.

Ask your clinician about

  • Probiotic Dairy

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Urinary Tract InfectionsMore likely
More likely to have UTIs based on 37,658 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Key Takeaways: About 150 million people get at least one UTI per year.

They're much more common in women.

Women at a high genetic risk may want to take precautions, such as staying hydrated and maintaining personal hygiene.

What you can do

  • Drink at Least 8 Glasses of Water a Day
    Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.
  • Probiotics

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
A further 15 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Athlete’s FootLess likely
Lower predisposition than 98% of people
Your result sits lower than 98% of the population.

What this actually is

Symptoms of athlete's foot include itching, stinging, and burning sensations between the toes or on soles of the feet.

The skin may also flake, peel, and crack, sometimes leading to pain, swelling, and blisters.

A distinctive sign is a scaly, red rash that itches intensely, often accompanied by a foul odor.

From your Immunity & Infections report
Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Risk factors include being under age 30, European ancestry, and smoking.

IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.

IBD only affects about 3 in 1000 people worldwide.

From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Inflammation & Autoimmunity report & Immunity & Infections

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (15)
  • Excessive Mast Cells — More likely, 97th percentile
  • Thyroid Inflammation — More likely, 96th percentile
  • Pancreas Inflammation — More likely, 95th percentile
  • Swollen Lymph Nodes — More likely, 94th percentile
  • Acute Bronchitis — More likely, 90th percentile
  • Urethra Inflammation — More likely, 88th percentile
  • C. difficile Infection — More likely, 87th percentile
  • Eye Inflammation — More likely, 84th percentile
  • Shigella Infection — More likely, 84th percentile
  • Crohn’s Disease — More likely, 66th percentile
  • Psoriasis — More likely, 65th percentile
  • Myocarditis — More likely
  • Nephritis — More likely
  • Long COVID — More likely
  • Pneumococcal Disease — More likely
Running above the typical range  (13)
  • HLA (Inflammation) — Higher activity, 80th percentile
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
  • IgA — Higher levels
  • IL-23R (Th17) — Higher levels
  • GPX1 (Glutathione/Detox) — Higher activity
  • MAOB (Dopamine/ Norepinephrine) — Higher activity
  • MAOA (Dopamine/Serotonin) — Higher activity
Running below the typical range  (13)
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
  • Gut Microbiome Diversity — Lower
  • UGT2A1 (Cognition) — Lower activity
  • GCLC (Glutathione & Detox) — Lower activity
  • GSTA1 (Detox/ Glutathione) — Lower activity
  • HRH1 (Allergies) — Lower activity
  • ALDH2 (Alcohol Sensitivity) — Lower activity
Working in your favour  (9)
  • Optic Nerve Inflammation — Less likely, 19th percentile
  • Ear Infection — Less likely, 19th percentile
  • Common Cold — Less likely, 9th percentile
  • Parasites — Less likely, 9th percentile
  • Staph Infection — Less likely, 8th percentile
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
  • HRH2 (Gut Health) — Better genetics
In line with most people  (90)
  • Respiratory Infections — Typical likelihood, 78th percentile
  • Sore Throat — Typical likelihood, 77th percentile
  • Mumps — Typical likelihood, 74th percentile
  • Inner Ear Infection — Typical likelihood, 72th percentile
  • Spleen Problems — Typical likelihood, 68th percentile
  • H. pylori — Typical likelihood, 67th percentile
  • Shingles — Typical likelihood, 65th percentile
  • Bone Infection — Typical likelihood, 65th percentile
  • Low White Blood Cells — Typical likelihood, 65th percentile
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Chlamydia — Typical likelihood, 62th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • EBV Infection — Typical likelihood, 48th percentile
  • Pneumonia — Typical likelihood, 46th percentile
  • Warts — Typical likelihood, 46th percentile
  • HPV Infection — Typical likelihood, 46th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Pink Eye — Typical likelihood, 33th percentile
  • Ringworm — Typical likelihood, 32th percentile
  • Impetigo (School Sores) — Typical likelihood, 30th percentile
  • Eczema — Typical likelihood, 29th percentile
  • Stomach Bug — Typical likelihood, 27th percentile
  • Leg Cellulitis — Typical likelihood, 23th percentile
  • IL-6 — Typical levels, 20th percentile
  • Strep Infection — Typical likelihood, 20th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Psoriatic Arthritis — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • IgA Nephropathy — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics
  • Tuberculosis — Typical likelihood
  • Whooping Cough (Pertussis) — Typical likelihood
  • HIV/AIDS — Typical likelihood
  • Malaria — Typical likelihood
  • Scarlet Fever — Typical likelihood
  • Gangrene — Typical likelihood
  • Symptomatic HTLV-1 Infection — Typical likelihood
  • Bifidobacterium — Typical levels
  • Bifidobacterium Longum — Typical levels
  • Bifidobacterium Breve — Typical levels
  • Bifidobacterium Bifidum — Typical levels
  • Glutathione — Typical function
  • VDR (Vitamin D) — Typical activity
  • IL6 Gene (Inflammation) — Typical activity
  • MUC1 (Immunity, Gut, Minerals) — Typical genetics
  • GPX4 (Selenium & Glutathione) — Typical activity
  • GATA3 (Allergies) — Typical activity
  • HLA-DQ (Gluten) — Typical genetics
  • Histamine Intolerance — Typical likelihood
  • NAT2 (Detox) — Intermediate

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-81D64E
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-81D64E · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Inflammation & Autoimmunity

Personalized Genetic Report
Inflammatory Gut ConditionsOther Inflammatory ConditionsAutoimmune Joint ConditionsAutoimmune Skin ConditionsOther Autoimmune ConditionsInflammation MarkersHLA GenesOther Inflammation Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-0FCD26
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-0FCD26
Panel
Inflammation & Autoimmunity
Results scored
80 of 83
Need attention
9
Report
Summary Report

What this report covers

Inflammatory Gut Conditions · Other Inflammatory Conditions · Autoimmune Joint Conditions · Autoimmune Skin Conditions · Other Autoimmune Conditions · Inflammation Markers · HLA Genes · Other Inflammation Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 80 results here, 9 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
2
Yoga30 minutes

Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Relates to: Crohn’s Disease, Pancreas Inflammation, Eye Inflammation, Psoriasis
relevance
3
Dietary Antioxidants

Avoid Cannabis Stop any form of cannabis use, including smoking, vaping, edibles, and topical applications.

Relates to: Pancreas Inflammation, Psoriasis, Myocarditis, Crohn’s Disease
relevance
4
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Pancreas Inflammation, Eye Inflammation
relevance
5
Antioxidant Supplements
Relates to: Pancreas Inflammation
relevance
6
Pancreatic Enzymes

based on the degree of pancreatic insufficiency and the fat content of the meal.

Relates to: Pancreas Inflammation, Psoriasis
relevance
7
Avoid Refined Sugar

Replace them with natural sugars found in fruits and whole grains.

Relates to: Crohn’s Disease, Myocarditis, Pancreas Inflammation
relevance
8
Autoimmune Protocol (AIP) Diet

Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Relates to: Crohn’s Disease, Eye Inflammation, Thyroid Inflammation
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Crohn’s Disease, Thyroid Inflammation, HLA-DOB (Inflammation), Psoriasis
relevance
2
Omega-3 (Fish Oil)
Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
relevance
3
Dietary Omega-3 Fatty Acids
Relates to: Crohn’s Disease, Myocarditis, Nephritis, Pancreas Inflammation
relevance
4
Probiotics
Relates to: Pancreas Inflammation, SH2B3 (Autoimmunity), Crohn’s Disease, NLRP3 (Gut Inflammation)
relevance
5
Curcumin
Relates to: NLRP3 (Gut Inflammation), Crohn’s Disease, Psoriasis, Eye Inflammation
relevance
6
Boswellia
Relates to: Crohn’s Disease
relevance

Your headline findings

Of the 80 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Pancreas InflammationMore likely
More likely to get pancreas inflammation based on 1,669 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

The pancreas is an organ located behind the stomach that releases crucial enzymes for carbs and fats digestion.

Pancreatitis is inflammation of the pancreas, which can be acute or chronic.

Potential risk factors for pancreatitis include [R, R, R]: Alcohol Cigarette smoking Obesity High blood lipids Certain medications Genetics Genetically predicted higher fasting insulin may be associated with acute and chronic pancreas inflammation.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Probiotics
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Urethra InflammationMore likely
More likely to have non-specific urethritis based infections
Your risk is greater than 88% of the population and lower than 12% of the population.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Eye InflammationMore likely
More likely to have uveitis based on 3,409 genetic variants we looked at
Your risk is greater than 84% of the population and lower than 16% of the population.

What this actually is

The management of uveitis involves addressing both the inflammation and the underlying cause if identified.

Typical treatments include corticosteroids to reduce the inflammation and drugs that manage the immune system's response.

Careful monitoring by an ophthalmologist is critical to prevent complications such as glaucoma, cataracts, and macular edema, all of which could lead to loss of vision.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Crohn’s DiseaseMore likely
More likely to get Crohn's disease based on 1,031,499 genetic variants we looked at
Your risk is greater than 66% of the population and lower than 34% of the population.

What this actually is

Aside from gastrointestinal symptoms, Crohn's Disease can also have systemic effects on the body, leading to issues such as anemia, skin rashes, arthritis, and eye inflammation.

The cause of Crohn's Disease is not fully understood, but it involves an abnormal immune response to the microorganisms in the intestine, in genetically susceptible individuals.

There's no known cure for Crohn's Disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission and healing of inflammation.

What you can do

  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
PsoriasisMore likely
More likely to have psoriasis based on 1,049,035 genetic variants we looked at
Your risk is greater than 65% of the population and lower than 35% of the population.

What this actually is

triggers include: infections, weather, skin injuries, stress, cigarette smoke, alcohol abuse, steroid withdrawal.

About 2% of Americans have psoriasis, mostly appearing in younger and older adults.

Even though the condition is rare, people with high genetic risk should understand and be wary of potential triggers.

What you can do

  • Pancreatic Enzymes
    based on the degree of pancreatic insufficiency and the fat content of the meal.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
MyocarditisMore likely
Higher predisposition than average

What this actually is

Myocarditis can be Viral parvovirus, and Bacterial Parasitic cruzi and Autoimmune Exposure to certain Allergic There is some myocarditis, associated with might influence how and other triggers Preventing avoiding avoiding toxic identify early symptoms of a palpitations.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Potassium
  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
A further 1 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Risk factors include being under age 30, European ancestry, and smoking.

IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.

IBD only affects about 3 in 1000 people worldwide.

From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Inflammation & Autoimmunity report
Optic Nerve InflammationLess likely
Lower predisposition than 81% of people
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Optic Nerve The causes of optic to autoimmune neuromyelitis indication of MS in infections can Recovery from optic weeks in most few months, some permanent vision corticosteroids to recovery of vision, among individuals.

From your Inflammation & Autoimmunity report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (1)
  • Nephritis — More likely
Running above the typical range  (8)
  • HLA (Inflammation) — Higher activity, 80th percentile
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
Running below the typical range  (7)
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour  (3)
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
In line with most people  (50)
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Eczema — Typical likelihood, 29th percentile
  • IL-6 — Typical levels, 20th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Psoriatic Arthritis — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • IgA Nephropathy — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-0FCD26
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-0FCD26 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Immunity & Infections

Personalized Genetic Report
Respiratory InfectionsSkin InfectionsGut InfectionsSexually Transmitted InfectionsOther InfectionsImmune System ProblemsGut MicrobiomeImmunity MarkersImmunity Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-1302D4
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-1302D4
Panel
Immunity & Infections
Results scored
76 of 77
Need attention
14
Report
Summary Report

What this report covers

Respiratory Infections · Skin Infections · Gut Infections · Sexually Transmitted Infections · Other Infections · Immune System Problems · Gut Microbiome · Immunity Markers · Immunity Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 76 results here, 14 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Immunity & Infections — The immune system is the body’s primary defense against infections, working tirelessly to ward off harmful viruses, bacteria, and other pathogens. However, genetic factors can influence how effectively your immune system responds to various infections and how prone you may be

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Safer Sex Practices

Reduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners.

Relates to: Genital Herpes, Flu
relevance
2
Probiotics
Relates to: C. difficile Infection, Gastrointestinal Infection, Yeast Infection, Flu
relevance
3
Regular Hand Washing

Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.

Relates to: Flu, C. difficile Infection, Gastrointestinal Infection, Eye Stye
relevance
4
Drink at Least 8 Glasses of Water a Day

Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.

Relates to: C. difficile Infection, Gastrointestinal Infection, Urinary Tract Infections, Acute Bronchitis
relevance
5
Good Hygiene Practices

Wash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home.

Relates to: Flu, C. difficile Infection
relevance
6
Airway Muscle Training30 minutes

Perform airway muscle training exercises daily for at least 30 minutes.

Relates to: Long COVID
relevance
7
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Long COVID
relevance
8
Avoid Close Contact With Infected People

Maintain a distance of at least 6 feet from people who are showing symptoms of respiratory illness, such as coughing or sneezing.

Relates to: Flu, C. difficile Infection
relevance
9
Topical Aloe Vera

Avoid using scented products like douches, sprays, or powders in the genital area.

Relates to: Yeast Infection, Urinary Tract Infections, Genital Herpes, Swollen Lymph Nodes
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Zinc
Relates to: Gastrointestinal Infection, C. difficile Infection, Flu, Shigella Infection
relevance
2
Good Oral Hygiene
Relates to: Yeast Infection, Flu, Gastrointestinal Infection, Pneumococcal Disease
relevance
3
Prebiotics
Relates to: Gut Microbiome Diversity, C. difficile Infection
relevance
4
Maintain Optimal Vitamin D Levels
Relates to: Urinary Tract Infections, Flu, Long COVID, C. difficile Infection
relevance
5
Lactobacillus Casei
Relates to: C. difficile Infection, Gastrointestinal Infection, Gut Microbiome Diversity, Flu
relevance

Your headline findings

Of the 76 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

FluMore likely
More likely to get the flu based on 8,860 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Flu (influenza) is a respiratory infection of the nose, throat and lungs, transferred via droplets that are either inhaled or picked up from surfaces.

Studies show that genetic factors can play a significant role in the risk of developing severe flu symptoms.

What you can do

  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
  • Good Hygiene Practices
    Wash your hands with soap and water for at least 20 seconds, especially before eating, after using the restroom, TA and when returning home.
  • Probiotics
From your Immunity & Infections report
Yeast InfectionMore likely
More likely to have yeast infections based on 104,352 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Candida albicans is a fungus that normally lives in and on the body.

If its environment changes and promotes its growth, Candida can multiply and lead to an infection.

This is called a yeast infection or candidiasis.

What you can do

  • Probiotics
  • Topical Aloe Vera
    Avoid using scented products like douches, sprays, or powders in the genital area.

Ask your clinician about

  • Good Oral Hygiene

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Gastrointestinal InfectionMore likely
More likely to get a GI infection based on 49,910 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Gastrointestinal (GI) infections are diseases of the digestive system.

They are caused by the invasion of microbes that do not usually live there.

The main sources of infection include: Person-to-person contact Consumption of contaminated food (e.g., undercooked or poorly stored meat, raw milk) Consumption of contaminated water (e.g., river or swimming pool water) Contact with contaminated objects (e.g., soil, work tools) Contact with animals or their feces (e.g., contact with farm animals and pets, visiting petting zoos) Risk factors for GI infections include [R, R, R, R, R, R].

What you can do

  • Probiotics
  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Eye StyeMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population ng treatments can help alleviate symptoms and lower than 1% of the population.

What this actually is

Styes can develop eyelashes become factors include: Poor hygiene: transfer Makeup use: remove makeup blockages.

Eye irritation: hygiene or Chronic are more prone Most styes heal on However, the and speed up Warm affected eyelid help the stye Massage: Gently may help applying warm Keep it clean: keeping it Avoid makeup makeup or further relievers can Preventive measures removing makeup the eyes with significantly eye infections.

What you can do

  • Regular Hand Washing
    Do this several times a day, especially before eating, after using the bathroom, after blowing your nose, coughing, or sneezing, and after touching garbage.
From your Immunity & Infections report
Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc
  • Good Oral Hygiene

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Genital HerpesMore likely
More likely to get genital herpes based on 284,981 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Genital herpes is a common sexually transmitted infection (STI), usually caused by the herpes simplex virus type 2 (HSV-2).

Genetics may also affect susceptibility to genital herpes.

Involved genes may play a role in the immune response, cell life cycle, and more.

What you can do

  • Safer Sex Practices
    Reduce the number of sexual partners you have, and get tested regularly for sexually transmitted infections (STIs), ideally every 3 to 6 months if you're sexually active with new or multiple partners.
  • Topical Aloe Vera
    Avoid using scented products like douches, sprays, or powders in the genital area.
From your Immunity & Infections report
Low NeutrophilsMore likely
More likely to have neutropenia based on 1,674 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Neutropenia is typically diagnosed through a complete blood count test, which evaluates the levels of various types of cells in the blood.

If neutropenia is detected, further tests may be required to determine its cause: Bone marrow biopsy: To examine the health and status of the bone marrow.

Blood tests: To check for infections, vitamin deficiencies (such as B12 and folate), and autoimmune disorders.

What you can do

  • Avoid Crowds
    Minimize your time in crowded places by scheduling your errands during off-peak hours, avoiding public events known to draw large crowds, and choosing less crowded routes or modes of transportation.

Ask your clinician about

  • Probiotic Dairy

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
Urinary Tract InfectionsMore likely
More likely to have UTIs based on 37,658 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Key Takeaways: About 150 million people get at least one UTI per year.

They're much more common in women.

Women at a high genetic risk may want to take precautions, such as staying hydrated and maintaining personal hygiene.

What you can do

  • Drink at Least 8 Glasses of Water a Day
    Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.
  • Probiotics

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Immunity & Infections report
A further 6 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Athlete’s FootLess likely
Lower predisposition than 98% of people
Your result sits lower than 98% of the population.

What this actually is

Symptoms of athlete's foot include itching, stinging, and burning sensations between the toes or on soles of the feet.

The skin may also flake, peel, and crack, sometimes leading to pain, swelling, and blisters.

A distinctive sign is a scaly, red rash that itches intensely, often accompanied by a foul odor.

From your Immunity & Infections report
Staph InfectionLess likely
Less likely to have a staph infection based on 56,947 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Factors that might increase the risk of a staph infection include: Current or recent hospitalization Having medical devices (e.g., catheters or feeding tubes) Skin injuries or disorders Weakened immune system (e.g., HIV/AIDS, diabetes, or cancer) Practicing contact sports.

Living in crowded conditions (e.g., military barracks or correctional facilities) Genetic variations in immunity genes may slightly increase the susceptibility to staph infection or its complications.

However, factors other than genetics seem to play a much bigger role.

From your Immunity & Infections report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Immunity & Infections report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (6)
  • Swollen Lymph Nodes — More likely, 94th percentile
  • Acute Bronchitis — More likely, 90th percentile
  • C. difficile Infection — More likely, 87th percentile
  • Shigella Infection — More likely, 84th percentile
  • Long COVID — More likely
  • Pneumococcal Disease — More likely
Running above the typical range  (5)
  • Basophils — Higher levels
  • IgA — Higher levels
  • IL-23R (Th17) — Higher levels
  • ABCB1 (Chronic Lyme) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
Running below the typical range  (6)
  • Gut Microbiome Diversity — Lower
  • UGT2A1 (Cognition) — Lower activity
  • GCLC (Glutathione & Detox) — Lower activity
  • GSTA1 (Detox/ Glutathione) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour  (3)
  • Ear Infection — Less likely, 19th percentile
  • Common Cold — Less likely, 9th percentile
  • Parasites — Less likely, 9th percentile
In line with most people  (45)
  • Respiratory Infections — Typical likelihood, 78th percentile
  • Sore Throat — Typical likelihood, 77th percentile
  • Mumps — Typical likelihood, 74th percentile
  • Inner Ear Infection — Typical likelihood, 72th percentile
  • Spleen Problems — Typical likelihood, 68th percentile
  • H. pylori — Typical likelihood, 67th percentile
  • Shingles — Typical likelihood, 65th percentile
  • Bone Infection — Typical likelihood, 65th percentile
  • Low White Blood Cells — Typical likelihood, 65th percentile
  • Chlamydia — Typical likelihood, 62th percentile
  • EBV Infection — Typical likelihood, 48th percentile
  • Pneumonia — Typical likelihood, 46th percentile
  • Warts — Typical likelihood, 46th percentile
  • HPV Infection — Typical likelihood, 46th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Pink Eye — Typical likelihood, 33th percentile
  • Ringworm — Typical likelihood, 32th percentile
  • Impetigo (School Sores) — Typical likelihood, 30th percentile
  • Stomach Bug — Typical likelihood, 27th percentile
  • Leg Cellulitis — Typical likelihood, 23th percentile
  • Strep Infection — Typical likelihood, 20th percentile
  • Tuberculosis — Typical likelihood
  • Whooping Cough (Pertussis) — Typical likelihood
  • HIV/AIDS — Typical likelihood
  • Malaria — Typical likelihood
  • Scarlet Fever — Typical likelihood
  • Gangrene — Typical likelihood
  • Sepsis — Typical likelihood
  • Symptomatic HTLV-1 Infection — Typical likelihood
  • Bifidobacterium — Typical levels
  • Bifidobacterium Longum — Typical levels
  • Bifidobacterium Breve — Typical levels
  • Bifidobacterium Bifidum — Typical levels
  • White Blood Cells — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Glutathione — Typical function
  • STAT3 (Th1/Th17) — Typical activity
  • VDR (Vitamin D) — Typical activity
  • IL6 Gene (Inflammation) — Typical activity
  • MUC1 (Immunity, Gut, Minerals) — Typical genetics
  • TLR4 (Inflammation) — Typical activity
  • GPX4 (Selenium & Glutathione) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • GATA3 (Allergies) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-1302D4
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-1302D4 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

HLA DNA Autoimmunity

Personalized Genetic Report
Autoimmunity & Inflammation
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-9A61BA
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-9A61BA
Panel
HLA DNA Autoimmunity
Results scored
7
Need attention
0
Report
Summary Report

What this report covers

Autoimmunity & Inflammation

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 7 results here, 0 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

HLA DNA Autoimmunity — Your immune system's ability to distinguish between "self" and "non-self" is largely influenced by your HLA (Human Leukocyte Antigen) genes. These genes act like your body's security system, playing a crucial role in how your immune system recognizes and responds to various threats.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: HLA-DOB (Inflammation)
relevance
2
Black Seed (Black Cumin)
Relates to: HLA-DOB (Inflammation)
relevance

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (2)
  • HLA (Inflammation) — Higher activity, 80th percentile
  • HLA-DOB (Inflammation) — Higher activity
In line with most people  (5)
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DQ (Gluten) — Typical genetics
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-9A61BA
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-9A61BA · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Histamine

Personalized Genetic Report
Histamine
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-E25A8C
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-E25A8C
Panel
Histamine
Results scored
12
Need attention
1
Report
Summary Report

What this report covers

Histamine

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 12 results here, 1 came back worth discussing with a clinician and 1 came back in your favour. Bring this document to your appointment.

What this package looks at

Histamine — Histamine is a crucial molecule that plays multiple roles in your body, from immune responses to neurotransmitter function and digestion. This analysis explores genetic variations that influence every aspect of histamine metabolism -from production and storage to breakdown and

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Dark Chocolate

Histamine v2 Eat dark chocolate with a cocoa content of at least 70-85%, limiting intake to about a day to gain cardiovascular and mood-related benefits without excessive calorie intake.

Relates to: MAOB (Dopamine/ Norepinephrine), MAOA (Dopamine/Serotonin)
relevance
2
Low-Histamine Diet

Exclude high-histamine foods such as aged cheeses, smoked meats, fermented products like sauerkraut and kombucha, alcohol, and preserved foods. for at least 4 weeks to observe any improvements in symptoms.

Relates to: Excessive Mast Cells
relevance
3
Avoid Exposure to Molds

Keep indoor humidity levels below 50% by using dehumidifiers or air conditioners, ensure proper ventilation in areas like bathrooms and kitchens, fix leaks promptly, and clean up any water damage within 24-48 hours to prevent mold growth.

Relates to: Excessive Mast Cells
relevance
4
Avoid Exposure to Heavy Metals

Check for lead-based paints in older homes and avoid cooking or storing food in uncoated metal containers.

Relates to: Excessive Mast Cells
relevance
5
Avoid Refined Sugar

Replace them with natural sugars found in fruits and whole grains.

Relates to: Excessive Mast Cells
relevance
6
Avoid Exposure to Solvents

Wear protective gloves and masks when using solvent-based products such as paint thinners, degreasers, or nail polish removers.

Relates to: Excessive Mast Cells
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Turmeric
Relates to: MAOB (Dopamine/ Norepinephrine), MAOA (Dopamine/Serotonin), Excessive Mast Cells
relevance
2
Quercetin
Relates to: Excessive Mast Cells
relevance
3
Maintain Optimal Vitamin D Levels
Relates to: MAOA (Dopamine/Serotonin), Excessive Mast Cells
relevance
4
Dietary Omega-3 Fatty Acids
Relates to: Excessive Mast Cells
relevance
5
Vitamin C
Relates to: Excessive Mast Cells
relevance
6
Rutin
Relates to: Excessive Mast Cells
relevance

Your headline findings

Of the 12 results in this package, these 1 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.

These mutations are usually acquired during a person's life rather than being inherited.

Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.

Ask your clinician about

  • Quercetin
  • Turmeric
  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Histamine report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

HRH2 (Gut Health)Better genetics
Lower predisposition than average

What this actually is

The most widely-investigated HRH2 polymorphism is rs2067474 (-1018 G>A).

Its minor ‘A’ allele may affect gene expression based on its position within the gene sequence but its exact contribution to HRH2 function hasn’t been established.

From your Histamine report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (3)
  • MAOB (Dopamine/ Norepinephrine) — Higher activity
  • MAOA (Dopamine/Serotonin) — Higher activity
  • HNMT (Histamine) — Higher activity
Running below the typical range  (2)
  • HRH1 (Allergies) — Lower activity
  • ALDH2 (Alcohol Sensitivity) — Lower activity
In line with most people  (5)
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Histamine Intolerance — Typical likelihood
  • DAO (Histamine) — Typical activity
  • IgE — Typical levels
  • NAT2 (Detox) — Intermediate

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-E25A8C
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-E25A8C · © 2026 Marrow Health.