Marrow
Genomics · Genetic Reports · Precision Wellness

Joint & Tendon Health Package

Personalized 4-Report Genetic Package
Joint & Tendon HealthBone HealthInjuriesPain
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-9E9326
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-9E9326
Reports in package
4
Results scored
89 of 98
Need attention
33
Report
Summary Report

The reports inside this package

This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Joint & Tendon Health27 results reported of 27 analytes · 50 recommendations
Bone Health17 results reported of 17 analytes · 50 recommendations
Injuries21 results reported of 21 analytes · 50 recommendations
Pain33 results reported of 33 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 89 results here, 33 came back worth discussing with a clinician and 8 came back in your favour. Bring this document to your appointment.

What this package looks at

Joint & Tendon Health — Joint and tendon health is essential for maintaining mobility, flexibility, and overall physical function. Genetic factors play a significant role in determining your susceptibility to various conditions that affect the joints and tendons, such as joint pain, arthritis, and tendon problems. While

Bone Health — Bone health is crucial for maintaining a strong skeletal system, mobility, and overall physical well-being. While lifestyle factors such as diet and exercise play important roles in bone health, genetics also significantly influences how strong and resilient your bones are.

Injuries — Injuries can significantly affect mobility, daily function, and quality of life. While accidents and physical activities are common causes of injury, genetics also plays a critical role in determining an individual’s susceptibility to certain types of injuries. Whether it's joint and tendon

Pain — We all experience pain from time to time, from stubbing a toe to hurting our knee or having a migraine attack. What makes us all different is the amount of pain we experience and how we handle it. There are lots of reasons for that, one of which is your DNA!

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Manual Therapy

Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), ACL Injury, Ankle Injury
relevance
2
Avoid Food Triggers

Try to limit caffeine to per day to avoid migraines.

Relates to: Migraines
relevance
3
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), ACL Injury, Ankle Injury
relevance
4
Shock Wave Therapy

Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.

Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement, Trigger Finger
relevance
5
Cognitive-Behavioral Therapy (CBT)

Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Relates to: Migraines, Chronic Pain, Fibromyalgia, Shoulder & Neck Pain
relevance
6
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, Long COVID, Jaw Disorders (TMJ), ACL Injury
relevance
7
Biofeedback

Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.

Relates to: Diabetic Neuropathy, Chronic Pain, Migraines, Shoulder & Neck Pain
relevance
8
Reduce Jaw Strain

Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.

Relates to: Jaw Disorders (TMJ)
relevance
9
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Chronic Pain, Migraines, Long COVID, Shoulder & Neck Pain
relevance
10
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Chronic Pain, Shoulder & Neck Pain
relevance
11
Core-Strengthening Exercises20 minutes

Aim to do TA these exercises for 20-30 minutes, 3 times a week.

Relates to: Low Back Injury, ACL Injury, Fibromyalgia, Abdominal Hernia
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Calcium, Hypoparathyroidism, Chronic Pain, Fibromyalgia
relevance
2
Magnesium
Relates to: Migraines, Chronic Pain, Cluster Headaches, Fibromyalgia
relevance
3
Dietary Calcium
Relates to: Hypoparathyroidism
relevance

Your headline findings

Of the 89 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Heel Pain (Plantar Fasciitis)More likely
More likely to have plantar fasciitis based on 28,598 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Factors that might increase the risk of developing plantar fasciitis include: Age, with it being most common between the ages of 40 and 60 Certain types of exercise, such as long-distance running or ballet dancing Foot mechanics, including having a high arch, flat feet, or an abnormal walking pattern Obesity, which places extra stress on the plantar fascia Occupations that require long periods of standing or walking on hard surfaces Wearing shoes with inadequate support Genetics While plantar fasciitis is primarily associated with environmental factors and physical stress on the foot, there is some evidence to suggest that genetic factors might play a role in predisposing certain individuals to the condition.

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
From your Joint & Tendon Health report
Groin HerniaMore likely
More likely to get a groin hernia based on 857,808 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

A hernia occurs when tissue from one body cavity bulges through an opening in your muscle wall into another.

Groin (inguinal) hernia is the most common type of hernia.

Others might occur as a result of: Increased pressure within the abdomen A preexisting weak spot in the abdominal wall Straining during bowel movements or urination Strenuous activity Pregnancy Chronic coughing or sneezing Genetics can have an impact on your susceptibility to a groin hernia.

From your Injuries report
Abdominal HerniaMore likely
More likely to have an abdominal hernia based on 11,533 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The following factors increase the risk of an abdominal hernia: Increased pressure in the abdomen: This can be due to heavy lifting, diarrhea, constipation, or persistent coughing or sneezing.

Weakness in the abdominal wall: This may be present at birth or develop later in life, often exacerbated by factors like age, chronic strain, or surgical incisions.

Pregnancy: It can put extra pressure on the abdomen.

What you can do

  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
From your Injuries report
MigrainesMore likely
More likely to have migraines based on 109,603 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: obesity, depression, stress, being female, blood vessel issues, brain chemical imbalances.

If you have a high genetic risk, take action on modifiable risk factors to help reduce overall risk.

About 16% of Americans regularly have migraines.

What you can do

  • Avoid Food Triggers
    Try to limit caffeine to per day to avoid migraines.
  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Neck ArthritisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.

What this actually is

As the disks in the cervical spine dehydrate and shrink, signs of osteoarthritis develop, including the formation of bony projections along the edges of bones (bone spurs).

Cervical spondylosis can sometimes lead to a narrowing of the space needed by the spinal cord and the nerve roots that pass through the spine to the rest of the body.

More likely to have When these nerve pathways are affected, individuals might 481,932 genetic experience neurological symptoms such as numbness, weakness, or tingling in the arms, hands, legs, or feet.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Femoral HerniaMore likely
More likely to have a femoral hernia based on 14,508 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

The symptoms of a femoral hernia can vary depending on its size and whether it becomes strangulated or not.

Patients may notice a small lump in the groin or upper thigh area that could be accompanied by discomfort or sharp pain, especially when straining or lifting heavy objects.

Strangulation, where the blood supply to the herniated tissue gets cut off, is a serious complication and can lead to nausea, vomiting, and severe pain and requires immediate medical attention to prevent further health risks.

From your Injuries report
Facial PainMore likely
Higher predisposition than 98% of people
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Diagnosing facial approach that can otolaryngologists, comprehensively and strategies could blocks, or surgery, For instance, sudden, severe resulting from Psychological also play pivotal the need for a plan.

What you can do

  • Biofeedback
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Low Back InjuryMore likely
More likely to have a low back injury based on 171,685 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Other risk factors include occupations involving repetitive motions or heavy lifting, prolonged sitting/standing, over 40, obesity, smoking, lack of physical activity, previous injury, and certain health conditions.

Lower back injuries are common among athletes, and account for 20% of workplace injuries.

If your genetic risk is high, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
  • Kinesio Taping
    Apply kinesio tape directly to the skin over the affected muscle or joint area.
From your Injuries report
A further 25 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Joint & Tendon Health report & Pain
Bone SpursLess likely
Less likely to have bone spurs based on 1,676 genetic variants we looked at
Your risk is greater than 5% of the population and lower than 95% of the population.

What this actually is

Bone spurs develop as a result of bone and joint degeneration and are primarily associated with the aging process.

However, they can also arise from underlying diseases and conditions that affect bone and joint health: Osteoarthritis: The most common cause of bone spurs, osteoarthritis involves the breakdown of cartilage, leading to joint damage and increased bone friction.

Spinal degeneration: Bone spurs commonly occur in the spine as a result of the degeneration of discs and joints, often due to aging.

From your Bone Health report
Tennis ElbowLess likely
Lower predisposition than 92% of people
Your risk is greater than 8% of the population s, and sometimes even surgery for severe and lower than 92% of the population.

What this actually is

Several factors elbow: Age: It's most Occupation: and arm, such this condition.

Certain sports: risk of tennis technique.

Genetics: Some that makes repetitive Managing tennis relieving cases.

From your Injuries report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (25)
  • Concussion — More likely, 96th percentile
  • Ear Pain — More likely, 94th percentile
  • ACL Injury — More likely, 92th percentile
  • Ankle Injury — More likely, 91th percentile
  • Shoulder Impingement — More likely, 90th percentile
  • Disc Degeneration — More likely, 90th percentile
  • Statin-Induced Muscle Pain — More likely, 90th percentile
  • Painful Urination — More likely, 88th percentile
  • Trigger Finger — More likely, 87th percentile
  • Herniated Disk — More likely, 87th percentile
  • Shoulder & Neck Pain — More likely, 84th percentile
  • Cluster Headaches — More likely, 82th percentile
  • Jaw Disorders (TMJ) — More likely, 81th percentile
  • Dupuytren’s Contracture — More likely, 80th percentile
  • Pressure Ulcers — More likely, 80th percentile
  • Chronic Pain — More likely, 80th percentile
  • Spinal Arthritis — More likely
  • Bone Cancer — More likely
  • Hypoparathyroidism — More likely
  • Calcium — Increased need
  • Vitamin K — Increased need
  • Painful Bladder Syndrome — More likely
  • Fibromyalgia — More likely
  • Diabetic Neuropathy — More likely
  • Long COVID — More likely
Running above the typical range  (3)
  • MMP1 (Collagen) — Higher activity
  • GC (Vitamin D) — Higher activity
  • TRPM8 (Pain) — Higher activity
Running below the typical range  (2)
  • TRPV1 (Pain) — Lower activity, 15th percentile
  • OPRM1 (Endorphins) — Lower activity
Working in your favour  (5)
  • Tendon Inflammation — Less likely, 19th percentile
  • Scoliosis — Less likely, 19th percentile
  • Tendon Injury — Less likely, 18th percentile
  • Ehlers-Danlos Syndrome (Progeroid — Less likely
  • ADAMTS5 (Joint Health) — Better genetics
In line with most people  (43)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Falls — Typical likelihood, 76th percentile
  • Back Pain — Typical likelihood, 76th percentile
  • Painful Intercourse — Typical likelihood, 74th percentile
  • Trigeminal Nerve Pain — Typical likelihood, 68th percentile
  • Muscle Pain — Typical likelihood, 68th percentile
  • Hip Fractures — Typical likelihood, 66th percentile
  • Bone Infection — Typical likelihood, 65th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Tension Headaches — Typical likelihood, 64th percentile
  • Spinal Canal Narrowing — Typical likelihood, 60th percentile
  • Gout — Typical likelihood, 58th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Headache — Typical likelihood, 51th percentile
  • Spinal Cord Injury — Typical likelihood, 46th percentile
  • Knee Injury — Typical likelihood, 45th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Joint Stiffness — Typical likelihood, 39th percentile
  • Rotator Cuff Injury — Typical likelihood, 38th percentile
  • Fractures — Typical likelihood, 37th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tendon Lining Inflammation — Typical likelihood, 36th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Toothache — Typical likelihood, 33th percentile
  • Stomach Pain — Typical likelihood, 27th percentile
  • Nerve Compression — Typical likelihood, 22th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Psoriatic Arthritis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • COL5A1 (Collagen) — Typical activity
  • Hyperparathyroidism — Typical likelihood
  • Vitamin D — Typical need
  • Phosphate — Typical levels
  • Magnesium — Typical need
  • VDR (Vitamin D) — Typical activity
  • CYP2R1 (Vitamin D) — Typical activity
  • Mononeuropathy — Typical likelihood
  • Peripheral Neuropathy — Typical likelihood
  • Neuropathic Pain — Typical likelihood
  • CNR1 (Cannabinoids) — Typical activity
  • SCN9A (Pain) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-9E9326
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-9E9326 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Joint & Tendon Health

Personalized Genetic Report
Joint HealthTendon HealthJoint Health Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-5012AC
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-5012AC
Panel
Joint & Tendon Health
Results scored
27
Need attention
8
Report
Summary Report

What this report covers

Joint Health · Tendon Health · Joint Health Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 27 results here, 8 came back worth discussing with a clinician and 5 came back in your favour. Bring this document to your appointment.

What this package looks at

Joint & Tendon Health — Joint and tendon health is essential for maintaining mobility, flexibility, and overall physical function. Genetic factors play a significant role in determining your susceptibility to various conditions that affect the joints and tendons, such as joint pain, arthritis, and tendon problems. While

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Manual Therapy

Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
2
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), Neck Arthritis
relevance
3
Shock Wave Therapy

Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.

Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement, Trigger Finger
relevance
4
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
5
Reduce Jaw Strain

Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.

Relates to: Jaw Disorders (TMJ)
relevance
6
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Shoulder Impingement
relevance
7
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Neck Arthritis
relevance
8
Good Posture

Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.

Relates to: Shoulder Impingement, Heel Pain (Plantar Fasciitis), Disc Degeneration, Spinal Arthritis
relevance
9
Stretching15 minutes

Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.

Relates to: Heel Pain (Plantar Fasciitis), Dupuytren’s Contracture, Spinal Arthritis
relevance
10
Topical CBD

Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.

Relates to: Jaw Disorders (TMJ), Disc Degeneration, Neck Arthritis, Spinal Arthritis
relevance
11
Myofascial Release

Incorporate myofascial release into your routine by using tools like foam rollers or massage balls, focusing on TA tense areas for about 5-20 minutes daily.

Relates to: Heel Pain (Plantar Fasciitis)
relevance
12
Apply Heat15 minutes

Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.

Relates to: Jaw Disorders (TMJ), Neck Arthritis, Spinal Arthritis
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Methylsulfonylmethane (MSM)
Relates to: Jaw Disorders (TMJ), Heel Pain (Plantar Fasciitis), Shoulder Impingement
relevance
2
Vitamin C
Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement
relevance

Your headline findings

Of the 27 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Heel Pain (Plantar Fasciitis)More likely
More likely to have plantar fasciitis based on 28,598 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Factors that might increase the risk of developing plantar fasciitis include: Age, with it being most common between the ages of 40 and 60 Certain types of exercise, such as long-distance running or ballet dancing Foot mechanics, including having a high arch, flat feet, or an abnormal walking pattern Obesity, which places extra stress on the plantar fascia Occupations that require long periods of standing or walking on hard surfaces Wearing shoes with inadequate support Genetics While plantar fasciitis is primarily associated with environmental factors and physical stress on the foot, there is some evidence to suggest that genetic factors might play a role in predisposing certain individuals to the condition.

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
From your Joint & Tendon Health report
Neck ArthritisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.

What this actually is

As the disks in the cervical spine dehydrate and shrink, signs of osteoarthritis develop, including the formation of bony projections along the edges of bones (bone spurs).

Cervical spondylosis can sometimes lead to a narrowing of the space needed by the spinal cord and the nerve roots that pass through the spine to the rest of the body.

More likely to have When these nerve pathways are affected, individuals might 481,932 genetic experience neurological symptoms such as numbness, weakness, or tingling in the arms, hands, legs, or feet.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Shoulder ImpingementMore likely
More likely to have shoulder impingement based on 1,676 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

Risk factors for shoulder impingement include: Age: It is more common in middle-aged and older adults due to wear and tear.

Activities: Overhead activities common in some sports and jobs can lead to impingement.

Trauma: A fall or blow to the shoulder can initiate impingement symptoms.

What you can do

  • Manual Therapy
    Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.
  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Exercise Therapy
    Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.
From your Joint & Tendon Health report
Disc DegenerationMore likely
More likely to have disc degeneration based on 844,435 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

As disc degeneration progresses, individuals may experience chronic back pain, stiffness, or reduced mobility.

In some cases, the narrowing of the disc space can lead to nerve compression, resulting in symptoms such as sciatica, which is characterized by radiating pain down one or both legs.

Moreover, the body may form bony growths called bone spurs in response to the instability, potentially exacerbating nerve compression and leading to further discomfort and disability.

What you can do

  • Good Posture
    Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Trigger FingerMore likely
More likely to have trigger finger based on 3 genetic variants we looked at
Your risk is greater than 87% of the population and lower than 13% of the population.

What this actually is

Risk factors for trigger finger include [R, R, R, R, R]: Hobbies or jobs that require repetitive hand motions or prolonged gripping Some chronic health conditions (e.g., diabetes, rheumatoid arthritis) Female sex Previous surgery for carpal tunnel syndrome Genetics The genes involved in this condition may alter the structure of tendons [R, R].

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
From your Joint & Tendon Health report
Jaw Disorders (TMJ)More likely
More likely to have a TMJ disorder based on 17,327 genetic variants we looked at
Your risk is greater than 81% of the population and lower than 19% of the population.

What this actually is

Key Takeaways: Genetics plays a role in factors that contribute to TMJ disorders, such as arthritis or teeth grinding.

These genes may affect bone and cartilage structure, and mental health.

Factors that may increase the risk of developing TMJ disorders include arthritis, jaw injury, teeth grinding or clenching, and connective tissue problems.

What you can do

  • Reduce Jaw Strain
    Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.
  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
From your Joint & Tendon Health report
Dupuytren’s ContractureMore likely
More likely to have a Dupuytren's contracture based on 311 genetic variants we looked at
Your risk is greater than 80% of the population and lower than 20% of the population.

What this actually is

This condition commonly occurs in older adults, and risk factors include Northern European ancestry, a family history of the condition, diabetes, and smoking.

Although pain is not always associated with Dupuytren’s contracture, the limitation in hand function and dexterity can significantly interfere with daily activities.

Treatment can range from observation to various invasive procedures, such as needle aponeurotomy, enzyme injections to break down the tissue cord, or in severe cases, surgical removal of the affected tissue.

What you can do

  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
  • Avoid Strenuous Activity
    Refrain from participating in high-intensity physical activities such as running, heavy weightlifting, and high-impact sports.
From your Joint & Tendon Health report
Spinal ArthritisMore likely
More likely to have spinal arthritis based on 977,839 genetic variants we looked at

What this actually is

The symptoms of spinal arthritis might progress gradually and can vary in severity.

Individuals with this condition often experience chronic low back or neck pain which can sometimes be accompanied by a grinding sensation or a feeling of bone-on-bone friction.

As the disease advances, it can lead to the development of bone spurs or osteophytes, which may impinge on nerve roots, potentially causing tingling, numbness, or weakness in the limbs.

What you can do

  • Good Posture
    Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.
  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Joint & Tendon Health report
Tendon InjuryLess likely
Less likely to have tendinopathy based on 6 genetic variants we looked at
Your risk is greater than 18% of the population and lower than 82% of the population.

What this actually is

Other risk factors include intense physical activity or certain sports, using improper training technique or equipment, doing repetitive tasks, age (over 40), being female, some chronic health conditions and medications.

About 16 million tendon and ligament injuries occur in the U.S. each year.

If you have a high genetic risk, you may lower your overall risk by taking action on those factors that you can change.

From your Joint & Tendon Health report
Tendon InflammationLess likely
Less likely to have tendon inflammation based on 1,657 genetic variants we looked at
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Potential risk factors for tendon inflammation include: Age: Tendinitis is more common as tendons become less flexible with age.

Occupations that involve repetitive motions or forceful exertion.

Certain sports, particularly those that involve repetitive movements.

From your Joint & Tendon Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • MMP1 (Collagen) — Higher activity
Working in your favour  (2)
  • Ehlers-Danlos Syndrome (Progeroid — Less likely
  • ADAMTS5 (Joint Health) — Better genetics
In line with most people  (13)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Gout — Typical likelihood, 58th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Joint Stiffness — Typical likelihood, 39th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tendon Lining Inflammation — Typical likelihood, 36th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Psoriatic Arthritis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • COL5A1 (Collagen) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-5012AC
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-5012AC · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Bone Health

Personalized Genetic Report
Bone Health ProblemsBone Health Nutrients
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-13784A
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-13784A
Panel
Bone Health
Results scored
17
Need attention
4
Report
Summary Report

What this report covers

Bone Health Problems · Bone Health Nutrients

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 17 results here, 4 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.

What this package looks at

Bone Health — Bone health is crucial for maintaining a strong skeletal system, mobility, and overall physical well-being. While lifestyle factors such as diet and exercise play important roles in bone health, genetics also significantly influences how strong and resilient your bones are.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Broccoli

Incorporate at least one cup of chopped broccoli, either steamed or raw, into your daily diet.

Relates to: Calcium, Vitamin K
relevance
2
Collard Greens

Incorporate at least one cup of cooked or two cups of raw collard greens into your diet 3-4 times a week.

Relates to: Calcium, Vitamin K
relevance
3
Kale

Aim for a balanced diet consisting mostly of plant-based foods and lean protein sources, adjusting portions sizes to meet your individual nutritional needs and health goals.

Relates to: Calcium, Vitamin K
relevance
4
Salmon

Choose wild-caught salmon when possible for higher omega-3 content.

Relates to: Calcium, Hypoparathyroidism
relevance
5
Sardines

Incorporate two to three servings of sardines into your diet each week.

Relates to: Calcium, Hypoparathyroidism
relevance
6
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Bone Cancer
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Calcium, Hypoparathyroidism, Vitamin K
relevance
2
Dietary Calcium
Relates to: Hypoparathyroidism
relevance
3
Vitamin D and Calcium
Relates to: Calcium, Bone Cancer, Hypoparathyroidism
relevance
4
Magnesium
Relates to: Hypoparathyroidism
relevance
5
Dietary Omega-3 Fatty Acids
Relates to: Bone Cancer
relevance

Your headline findings

Of the 17 results in this package, these 4 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Bone CancerMore likely
More likely to have bone cancer based on 24,472 genetic variants we looked at

What this actually is

The exact causes of bone cancer are not well understood, but several factors can increase the risk: Genetic disorders: Certain inherited genetic disorders, such as hereditary retinoblastoma and Li-Fraumeni syndrome, are linked to a higher risk of bone cancer.

Previous radiation therapy: Exposure to high doses of radiation, such as those used in previous cancer treatments, can increase the risk.

Paget’s disease: This bone condition, mostly seen in elderly people, may increase the risk of developing osteosarcoma.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Ask your clinician about

  • Vitamin D and Calcium
  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
HypoparathyroidismMore likely
Higher predisposition than average

What this actually is

The condition can following surgical remove the Management of and vitamin D prevent symptoms.

Some patients may of their calcium quality of life. offers a more their use remains daily injections.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Dietary Calcium
  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
CalciumIncreased need
Likely increased need for calcium based on 49,961 genetic variants we looked at

What this actually is

Key Takeaways: The amount of calcium in the blood at any given time is controlled by vitamin D and parathyroid hormone.

Much of the world's population is at risk for low calcium.

Beyond diet, it is important to maintain adequate vitamin D levels as well.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Maintain Optimal Vitamin D Levels
  • Vitamin D and Calcium

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
Vitamin KIncreased need
Likely increased vitamin K need based on 11 genetic variants we looked at

What this actually is

Key Takeaways: Genes involved in higher or lower vitamin K levels may influence vitamin K breakdown, fat metabolism, and collagen and bone formation.

Having low vitamin K levels may contribute to bone health issues like osteoporosis.

is essential for blood clotting and bone health.

What you can do

  • Broccoli
    Incorporate at least one cup of chopped broccoli, either steamed or raw, into your daily diet.
  • Collard Greens
    Incorporate at least one cup of cooked or two cups of raw collard greens into your diet 3-4 times a week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Bone SpursLess likely
Less likely to have bone spurs based on 1,676 genetic variants we looked at
Your risk is greater than 5% of the population and lower than 95% of the population.

What this actually is

Bone spurs develop as a result of bone and joint degeneration and are primarily associated with the aging process.

However, they can also arise from underlying diseases and conditions that affect bone and joint health: Osteoarthritis: The most common cause of bone spurs, osteoarthritis involves the breakdown of cartilage, leading to joint damage and increased bone friction.

Spinal degeneration: Bone spurs commonly occur in the spine as a result of the degeneration of discs and joints, often due to aging.

From your Bone Health report
ScoliosisLess likely
Less likely to have scolisosis based on 541,912 genetic variants we looked at
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

The impact of scoliosis on an individual can range from negligible to severe, potentially leading to discomfort, pain, and in some cases, respiratory and cardiovascular issues due to the distortion of the ribcage.

Treatment options depend on the severity and progression of the curve and can include observation, bracing, or surgical intervention.

Bracing is commonly used to prevent further progression of the curve in growing children and adolescents, while surgery may be reserved for more severe cases to correct and stabilize the spine.

From your Bone Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • GC (Vitamin D) — Higher activity
In line with most people  (10)
  • Bone Infection — Typical likelihood, 65th percentile
  • Spinal Canal Narrowing — Typical likelihood, 60th percentile
  • Fractures — Typical likelihood, 37th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Hyperparathyroidism — Typical likelihood
  • Vitamin D — Typical need
  • Phosphate — Typical levels
  • Magnesium — Typical need
  • VDR (Vitamin D) — Typical activity
  • CYP2R1 (Vitamin D) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-13784A
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-13784A · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Injuries

Personalized Genetic Report
Joint & Tendon InjuriesBack & Spine InjuriesOther Injuries
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-698C06
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-698C06
Panel
Injuries
Results scored
21
Need attention
10
Report
Summary Report

What this report covers

Joint & Tendon Injuries · Back & Spine Injuries · Other Injuries

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 21 results here, 10 came back worth discussing with a clinician and 3 came back in your favour. Bring this document to your appointment.

What this package looks at

Injuries — Injuries can significantly affect mobility, daily function, and quality of life. While accidents and physical activities are common causes of injury, genetics also plays a critical role in determining an individual’s susceptibility to certain types of injuries. Whether it's joint and tendon

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, ACL Injury, Ankle Injury, Low Back Injury
relevance
2
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, ACL Injury, Low Back Injury
relevance
3
Core-Strengthening Exercises20 minutes

Aim to do TA these exercises for 20-30 minutes, 3 times a week.

Relates to: Low Back Injury, ACL Injury, Abdominal Hernia, Ankle Injury
relevance
4
Stability Training30 minutes

Integrate stability exercises into your workout routine 2-3 times per week.

Relates to: Ankle Injury, ACL Injury, Low Back Injury
relevance
5
Good Posture

Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.

Relates to: Shoulder Impingement, Low Back Injury, Pressure Ulcers
relevance
6
Jumping15 minutes

Aim for at least 3 TA sessions per week, each session lasting 10-15 minutes.

Relates to: ACL Injury, Ankle Injury
relevance
7
Compression Therapy

Choose a compression level appropriate for your condition (mild, moderate, or high), as advised by a healthcare professional.

Relates to: Pressure Ulcers, Shoulder Impingement, ACL Injury
relevance
8
Kinesio Taping

Apply kinesio tape directly to the skin over the affected muscle or joint area.

Relates to: Low Back Injury, Shoulder Impingement
relevance
9
Topical Aloe Vera

Apply a thin layer of pure aloe vera gel extracted directly from the aloe plant or an aloe vera-based product directly to the affected area.

Relates to: Pressure Ulcers, Ankle Injury
relevance
10
Manual Therapy

Schedule a session with a certified manual therapist, such as a physical therapist or chiropractor, once a week for at least 3 to 6 weeks.

Relates to: Shoulder Impingement, ACL Injury, Ankle Injury, Low Back Injury
relevance
11
Focused Attention Meditation20 minutes

TA breathing without letting your mind wander.

Relates to: Concussion
relevance
12
Pet Therapy30 minutes

Engage with a pet, such as a dog or cat, for at least 15-30 minutes a day.

Relates to: Concussion
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Vitamin C
Relates to: ACL Injury, Ankle Injury, Shoulder Impingement, Pressure Ulcers
relevance
2
Citicoline (CDP Choline)
Relates to: Concussion
relevance

Your headline findings

Of the 21 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Groin HerniaMore likely
More likely to get a groin hernia based on 857,808 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

A hernia occurs when tissue from one body cavity bulges through an opening in your muscle wall into another.

Groin (inguinal) hernia is the most common type of hernia.

Others might occur as a result of: Increased pressure within the abdomen A preexisting weak spot in the abdominal wall Straining during bowel movements or urination Strenuous activity Pregnancy Chronic coughing or sneezing Genetics can have an impact on your susceptibility to a groin hernia.

From your Injuries report
Abdominal HerniaMore likely
More likely to have an abdominal hernia based on 11,533 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The following factors increase the risk of an abdominal hernia: Increased pressure in the abdomen: This can be due to heavy lifting, diarrhea, constipation, or persistent coughing or sneezing.

Weakness in the abdominal wall: This may be present at birth or develop later in life, often exacerbated by factors like age, chronic strain, or surgical incisions.

Pregnancy: It can put extra pressure on the abdomen.

What you can do

  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
From your Injuries report
Femoral HerniaMore likely
More likely to have a femoral hernia based on 14,508 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

The symptoms of a femoral hernia can vary depending on its size and whether it becomes strangulated or not.

Patients may notice a small lump in the groin or upper thigh area that could be accompanied by discomfort or sharp pain, especially when straining or lifting heavy objects.

Strangulation, where the blood supply to the herniated tissue gets cut off, is a serious complication and can lead to nausea, vomiting, and severe pain and requires immediate medical attention to prevent further health risks.

From your Injuries report
Low Back InjuryMore likely
More likely to have a low back injury based on 171,685 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Other risk factors include occupations involving repetitive motions or heavy lifting, prolonged sitting/standing, over 40, obesity, smoking, lack of physical activity, previous injury, and certain health conditions.

Lower back injuries are common among athletes, and account for 20% of workplace injuries.

If your genetic risk is high, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Core-Strengthening Exercises 20 minutes
    Aim to do TA these exercises for 20-30 minutes, 3 times a week.
  • Kinesio Taping
    Apply kinesio tape directly to the skin over the affected muscle or joint area.
From your Injuries report
ConcussionMore likely
More likely to have a concussion based on 341,037 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

Factors that might increase the risk of getting a concussion include: Participation in high-impact or collision sports such as football, hockey, soccer, or boxing.

Falling, especially in young children and older adults.

Being involved in a motor vehicle accident.

What you can do

  • Focused Attention Meditation 20 minutes
    TA breathing without letting your mind wander.
  • Pet Therapy 30 minutes
    Engage with a pet, such as a dog or cat, for at least 15-30 minutes a day.

Ask your clinician about

  • Citicoline (CDP Choline)

Named only. Marrow gives no dose and does not recommend these.

From your Injuries report
ACL InjuryMore likely
More likely to tear an ACL based on 71,152 genetic variants we looked at
Your risk is greater than 92% of the population and lower than 8% of the population.

What this actually is

The anterior cruciate ligament (ACL) is a strong band of tissue that connects the bone in your thigh to the bone in your shin.

Damage to the ACL may cause it to tear partially or completely.

An ACL tear can occur if the knee moves suddenly or awkwardly.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Jumping 15 minutes
    Aim for at least 3 TA sessions per week, each session lasting 10-15 minutes.

Ask your clinician about

  • Vitamin C

Named only. Marrow gives no dose and does not recommend these.

From your Injuries report
Ankle InjuryMore likely
More likely to have an ankle injury based on 19,077 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.

What this actually is

The ankle is a joint that connects the bones of the foot to the bones of the leg.

It can bend sideways, upward, and downard.

This is called a sprained ankle [R, R, R].

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Stability Training 30 minutes
    Integrate stability exercises into your workout routine 2-3 times per week.
  • Jumping 15 minutes
    Aim for at least 3 TA sessions per week, each session lasting 10-15 minutes.
From your Injuries report
Shoulder ImpingementMore likely
More likely to have shoulder impingement based on 1,676 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

Risk factors for shoulder impingement include: Age: It is more common in middle-aged and older adults due to wear and tear.

Activities: Overhead activities common in some sports and jobs can lead to impingement.

Trauma: A fall or blow to the shoulder can initiate impingement symptoms.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Exercise Therapy
    Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.
  • Good Posture
    Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.
From your Injuries report
A further 2 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Tennis ElbowLess likely
Lower predisposition than 92% of people
Your risk is greater than 8% of the population s, and sometimes even surgery for severe and lower than 92% of the population.

What this actually is

Several factors elbow: Age: It's most Occupation: and arm, such this condition.

Certain sports: risk of tennis technique.

Genetics: Some that makes repetitive Managing tennis relieving cases.

From your Injuries report
Tendon InjuryLess likely
Less likely to have tendinopathy based on 6 genetic variants we looked at
Your risk is greater than 18% of the population and lower than 82% of the population.

What this actually is

Other risk factors include intense physical activity or certain sports, using improper training technique or equipment, doing repetitive tasks, age (over 40), being female, some chronic health conditions and medications.

About 16 million tendon and ligament injuries occur in the U.S. each year.

If you have a high genetic risk, you may lower your overall risk by taking action on those factors that you can change.

From your Injuries report
Tendon InflammationLess likely
Less likely to have tendon inflammation based on 1,657 genetic variants we looked at
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Potential risk factors for tendon inflammation include: Age: Tendinitis is more common as tendons become less flexible with age.

Occupations that involve repetitive motions or forceful exertion.

Certain sports, particularly those that involve repetitive movements.

From your Injuries report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (2)
  • Herniated Disk — More likely, 87th percentile
  • Pressure Ulcers — More likely, 80th percentile
In line with most people  (8)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Falls — Typical likelihood, 76th percentile
  • Hip Fractures — Typical likelihood, 66th percentile
  • Spinal Cord Injury — Typical likelihood, 46th percentile
  • Knee Injury — Typical likelihood, 45th percentile
  • Rotator Cuff Injury — Typical likelihood, 38th percentile
  • Fractures — Typical likelihood, 37th percentile
  • COL5A1 (Collagen) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-698C06
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-698C06 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Pain

Personalized Genetic Report
Chronic PainMusculoskeletal PainAcute PainHeadachesPain Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-A03659
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-A03659
Panel
Pain
Results scored
33
Need attention
12
Report
Summary Report

What this report covers

Chronic Pain · Musculoskeletal Pain · Acute Pain · Headaches · Pain Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 33 results here, 12 came back worth discussing with a clinician and 1 came back in your favour. Bring this document to your appointment.

What this package looks at

Pain — We all experience pain from time to time, from stubbing a toe to hurting our knee or having a migraine attack. What makes us all different is the amount of pain we experience and how we handle it. There are lots of reasons for that, one of which is your DNA!

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Food Triggers

Try to limit caffeine to per day to avoid migraines.

Relates to: Migraines
relevance
2
Cognitive-Behavioral Therapy (CBT)

Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Relates to: Migraines, Chronic Pain, Fibromyalgia, Shoulder & Neck Pain
relevance
3
Biofeedback

Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.

Relates to: Diabetic Neuropathy, Chronic Pain, Migraines, Shoulder & Neck Pain
relevance
4
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Long COVID
relevance
5
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Chronic Pain, Migraines, Long COVID, Shoulder & Neck Pain
relevance
6
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Chronic Pain, Shoulder & Neck Pain, Diabetic Neuropathy, Fibromyalgia
relevance
7
Meditation30 minutes

Set aside 10-20 minutes each day in a quiet space without distractions to practice meditation.

Relates to: Migraines, Chronic Pain, Fibromyalgia, Long COVID
relevance
8
Massage30 minutes

Choose a type of TA massage that suits your specific needs, such as Swedish for relaxation or deep tissue for muscle tension.

Relates to: Shoulder & Neck Pain, Chronic Pain, Fibromyalgia, Facial Pain
relevance
9
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Shoulder & Neck Pain, Diabetic Neuropathy
relevance
10
Drink at Least 8 Glasses of Water a Day

Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.

Relates to: Migraines, Painful Urination
relevance
11
Hydrogen Water

Drink 1.5 to 2 liters of hydrogen-rich water daily, spread out over the course of the day.

Relates to: Migraines, Long COVID, Painful Bladder Syndrome
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Magnesium
Relates to: Migraines, Chronic Pain, Cluster Headaches, Fibromyalgia
relevance
2
Coenzyme Q10 (CoQ10)
Relates to: Migraines, Fibromyalgia, Diabetic Neuropathy, Long COVID
relevance
3
Riboflavin (Vitamin B2)
Relates to: Migraines, Facial Pain
relevance

Your headline findings

Of the 33 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

MigrainesMore likely
More likely to have migraines based on 109,603 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Risk factors include: obesity, depression, stress, being female, blood vessel issues, brain chemical imbalances.

If you have a high genetic risk, take action on modifiable risk factors to help reduce overall risk.

About 16% of Americans regularly have migraines.

What you can do

  • Avoid Food Triggers
    Try to limit caffeine to per day to avoid migraines.
  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Facial PainMore likely
Higher predisposition than 98% of people
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Diagnosing facial approach that can otolaryngologists, comprehensively and strategies could blocks, or surgery, For instance, sudden, severe resulting from Psychological also play pivotal the need for a plan.

What you can do

  • Biofeedback
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Ear PainMore likely
Higher predisposition than 94% of people
Your risk is greater than 94% of the population and lower than 6% of the population.

What this actually is

Ear pain may not itself; it can conditions that otalgia.

Sinus dental issues, and to the ear.

Diagnosis of the comprehensive exam, audiometric studies.

What you can do

  • Apply Heat 15 minutes
    Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.
  • Topical Peppermint Oil
    Do this no more than 2-3 times daily.
From your Pain report
Statin-Induced Muscle PainMore likely
More likely to have statin-induced muscle pain based on 38 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

The exact mechanism by which statins cause muscle injury is not completely understood, but it is believed to be related to the depletion of coenzyme Q10, a key component in muscle energy production, or effects on muscle cell membranes and protein synthesis.

Risk factors for developing statin-induced myopathy include higher statin dosages, advanced age, female sex, smaller body frame, concurrent use of certain medications, and pre-existing conditions such as kidney disease.

Most patients see improvement in symptoms after discontinuation of the statin, but the condition necessitates careful balancing of the benefits of cholesterol lowering against the discomfort and potential harm of muscle symptoms.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Coenzyme Q10 (CoQ10)

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Painful UrinationMore likely
More likely to have painful urination based on 786,605 genetic variants we looked at
Your risk is greater than 88% of the population and lower than 12% of the population.

What this actually is

Apart from other conditions or obstruct the flow prostate issues hyperplasia (BPH) infections or contribute to Other contributors certain harsh soaps or crucial when depends on cause.

What you can do

  • Drink at Least 8 Glasses of Water a Day
    Consume a total of at least (or approximately 1.9 liters) of water over the course of the day.
  • Apply Heat 15 minutes
    Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.
From your Pain report
Shoulder & Neck PainMore likely
More likely to have shoulder and neck pain based on 924,669 genetic variants we looked at
Your risk is greater than 84% of the population and lower than 16% of the population.

What this actually is

Key Takeaways: About 1 in 5 adults have neck or shoulder pain.

Other risk factors include: poor posture, prolonged sitting, poor sleep position, injury and overuse, stress, and older age.

If you have high genetic risk or are experiencing symptoms, take action on modifiable factors like posture and sleep position.

What you can do

  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Massage 30 minutes
    Choose a type of TA massage that suits your specific needs, such as Swedish for relaxation or deep tissue for muscle tension.
From your Pain report
Cluster HeadachesMore likely
More likely to have cluster headaches based on 980 genetic variants we looked at
Your risk is greater than 82% of the population and lower than 18% of the population.

What this actually is

A cluster headache is a type of severe headache with bouts of frequent attacks, known as cluster periods.

Attacks may be triggered by: Alcohol High altitudes Bright light Heavy physical activity Heat Eating foods high in nitrites Certain medicines Illicit drugs like cocaine Some of the risk factors for cluster headaches include: Male sex Age 20 to 40 Smoking Genetics Genetics may explain about 25% of the differences in people’s odds of cluster headaches [R, R].

What you can do

  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Ask your clinician about

  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Pain report
Chronic PainMore likely
More likely to experience chronic pain based on 611,315 genetic variants we looked at
Your risk is greater than 80% of the population and lower than 20% of the population.

What this actually is

Key Takeaways: About 1 in 5 Americans report experiencing some form of chronic pain.

Risk factors include being female, older age, poverty, previous injury, mental health problems, and your genetics.

With a high genetic risk, you may want to be more mindful of other factors that can increase risk.

What you can do

  • Cognitive-Behavioral Therapy (CBT)
    Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
  • Biofeedback
    Practice the techniques learned during sessions at home daily to improve symptoms and manage your condition.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
From your Pain report
A further 4 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Pain report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (4)
  • Painful Bladder Syndrome — More likely
  • Fibromyalgia — More likely
  • Diabetic Neuropathy — More likely
  • Long COVID — More likely
Running above the typical range  (1)
  • TRPM8 (Pain) — Higher activity
Running below the typical range  (2)
  • TRPV1 (Pain) — Lower activity, 15th percentile
  • OPRM1 (Endorphins) — Lower activity
In line with most people  (17)
  • Back Pain — Typical likelihood, 76th percentile
  • Painful Intercourse — Typical likelihood, 74th percentile
  • Trigeminal Nerve Pain — Typical likelihood, 68th percentile
  • Muscle Pain — Typical likelihood, 68th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Tension Headaches — Typical likelihood, 64th percentile
  • Chest Pain (Angina) — Typical likelihood, 52th percentile
  • Headache — Typical likelihood, 51th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Toothache — Typical likelihood, 33th percentile
  • Stomach Pain — Typical likelihood, 27th percentile
  • Nerve Compression — Typical likelihood, 22th percentile
  • Mononeuropathy — Typical likelihood
  • Peripheral Neuropathy — Typical likelihood
  • Neuropathic Pain — Typical likelihood
  • CNR1 (Cannabinoids) — Typical activity
  • SCN9A (Pain) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-A03659
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-A03659 · © 2026 Marrow Health.