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Genomics · Genetic Reports · Precision Wellness

Longevity & Healthy Aging Package

Personalized 6-Report Genetic Package
Longevity & Healthy AgingMitochondrial SupportBone HealthJoint & Tendon HealthInflammation & AutoimmunityToxins & Detox
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-4F289A
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-4F289A
Reports in package
6
Results scored
206 of 246
Need attention
30
Report
Summary Report

The reports inside this package

This one document contains 6 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Longevity & Healthy Aging29 results reported of 33 analytes · 50 recommendations
Mitochondrial Support28 results reported of 28 analytes · 50 recommendations
Bone Health17 results reported of 17 analytes · 50 recommendations
Joint & Tendon Health27 results reported of 27 analytes · 50 recommendations
Inflammation & Autoimmunity80 results reported of 83 analytes · 50 recommendations
Toxins & Detox55 results reported of 58 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 206 results here, 30 came back worth discussing with a clinician and 17 came back in your favour. Bring this document to your appointment.

What this package looks at

Longevity & Healthy Aging — Longevity is a fascinating and complex area of study that encompasses not only the length of life but also the quality of life as we age. Genetic factors play a significant role in determining how long we live and how well we age.

Mitochondrial Support — Think of mitochondria as tiny power plants inside each of your cells, converting the food you eat into energy that keeps you alive and thriving. But these remarkable cellular structures do much more than just produce energy -they're key players in your overall health and vitality.

Bone Health — Bone health is crucial for maintaining a strong skeletal system, mobility, and overall physical well-being. While lifestyle factors such as diet and exercise play important roles in bone health, genetics also significantly influences how strong and resilient your bones are.

Joint & Tendon Health — Joint and tendon health is essential for maintaining mobility, flexibility, and overall physical function. Genetic factors play a significant role in determining your susceptibility to various conditions that affect the joints and tendons, such as joint pain, arthritis, and tendon problems. While

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

Toxins & Detox — The impact of environmental toxins on health is an increasingly important topic in personalized health and functional medicine. Our genetic makeup plays a significant role in how our bodies process, detoxify, and respond to various toxins.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Manual Therapy

Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
2
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Artery Hardening, Frailty, PPARD (Longevity), Prostate Cancer
relevance
3
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), Neck Arthritis
relevance
4
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
5
Shock Wave Therapy

Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.

Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement, Trigger Finger
relevance
6
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Colorectal Cancer, Artery Hardening, PPARD (Longevity), Prostate Cancer
relevance
7
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
8
Reduce Jaw Strain

Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.

Relates to: Jaw Disorders (TMJ)
relevance
9
Eat Fiber-Rich Foods

grams per day, spread out over all meals.

Relates to: Colorectal Cancer, Artery Hardening
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Calcium, Hypoparathyroidism, Crohn’s Disease, Thyroid Inflammation
relevance
2
Glutathione supplements
Relates to: UGT2A1 (Cognition)
relevance
3
N-acetylcysteine (NAC)
Relates to: UGT2A1 (Cognition), Aluminum
relevance
4
Green Tea
Relates to: Prostate Cancer, Artery Hardening, Colorectal Cancer, Aluminum
relevance
5
Omega-3 (Fish Oil)
Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
relevance

Your headline findings

Of the 206 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Heel Pain (Plantar Fasciitis)More likely
More likely to have plantar fasciitis based on 28,598 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Factors that might increase the risk of developing plantar fasciitis include: Age, with it being most common between the ages of 40 and 60 Certain types of exercise, such as long-distance running or ballet dancing Foot mechanics, including having a high arch, flat feet, or an abnormal walking pattern Obesity, which places extra stress on the plantar fascia Occupations that require long periods of standing or walking on hard surfaces Wearing shoes with inadequate support Genetics While plantar fasciitis is primarily associated with environmental factors and physical stress on the foot, there is some evidence to suggest that genetic factors might play a role in predisposing certain individuals to the condition.

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
From your Joint & Tendon Health report
Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Neck ArthritisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.

What this actually is

As the disks in the cervical spine dehydrate and shrink, signs of osteoarthritis develop, including the formation of bony projections along the edges of bones (bone spurs).

Cervical spondylosis can sometimes lead to a narrowing of the space needed by the spinal cord and the nerve roots that pass through the spine to the rest of the body.

More likely to have When these nerve pathways are affected, individuals might 481,932 genetic experience neurological symptoms such as numbness, weakness, or tingling in the arms, hands, legs, or feet.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.

These mutations are usually acquired during a person's life rather than being inherited.

Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.

What you can do

  • Avoid Exposure to Molds
    Keep indoor humidity levels below 50% by using dehumidifiers or air conditioners, ensure proper ventilation in areas like bathrooms and kitchens, fix leaks promptly, and clean up any water damage within 24-48 hours to prevent mold growth.

Ask your clinician about

  • Quercetin
  • Rutin

Named only. Marrow gives no dose and does not recommend these.

From your Mitochondrial Support report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.

Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.

The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Eat Fiber-Rich Foods
    grams per day, spread out over all meals.
From your Longevity & Healthy Aging report
Pancreas InflammationMore likely
More likely to get pancreas inflammation based on 1,669 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

The pancreas is an organ located behind the stomach that releases crucial enzymes for carbs and fats digestion.

Pancreatitis is inflammation of the pancreas, which can be acute or chronic.

Potential risk factors for pancreatitis include [R, R, R]: Alcohol Cigarette smoking Obesity High blood lipids Certain medications Genetics Genetically predicted higher fasting insulin may be associated with acute and chronic pancreas inflammation.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Probiotics
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Prostate CancerMore likely
More likely to get prostate cancer based on 1,049,413 genetic variants we looked at
Your risk is greater than 94% of the population and lower than 6% of the population.

What this actually is

The exact cause of prostate cancer is not clearly understood, but several factors have been identified that increase the risk of developing this disease: Age: The risk increases significantly after age 50, and it is most common in men over 65.

Family history: Having a father or brother with prostate cancer more than doubles a man’s risk.

Race/Ethnicity: African-American men have a higher risk of prostate cancer than men of other races.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.

Ask your clinician about

  • Green Tea
  • Green Tea Extract

Named only. Marrow gives no dose and does not recommend these.

From your Longevity & Healthy Aging report
A further 22 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.

About 60-70% of the differences in people’s cognitive decline may come from genetics.

For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].

From your Longevity & Healthy Aging report
Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Joint & Tendon Health report
Bone SpursLess likely
Less likely to have bone spurs based on 1,676 genetic variants we looked at
Your risk is greater than 5% of the population and lower than 95% of the population.

What this actually is

Bone spurs develop as a result of bone and joint degeneration and are primarily associated with the aging process.

However, they can also arise from underlying diseases and conditions that affect bone and joint health: Osteoarthritis: The most common cause of bone spurs, osteoarthritis involves the breakdown of cartilage, leading to joint damage and increased bone friction.

Spinal degeneration: Bone spurs commonly occur in the spine as a result of the degeneration of discs and joints, often due to aging.

From your Bone Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (22)
  • Shoulder Impingement — More likely, 90th percentile
  • Disc Degeneration — More likely, 90th percentile
  • Frailty — More likely, 89th percentile
  • Urethra Inflammation — More likely, 88th percentile
  • Trigger Finger — More likely, 87th percentile
  • Eye Inflammation — More likely, 84th percentile
  • Jaw Disorders (TMJ) — More likely, 81th percentile
  • Dupuytren’s Contracture — More likely, 80th percentile
  • Colorectal Cancer — More likely, 73th percentile
  • Crohn’s Disease — More likely, 66th percentile
  • Psoriasis — More likely, 65th percentile
  • PPARD (Longevity) — Worse
  • Mitochondrial Health (Functional) — Worse
  • Bone Cancer — More likely
  • Hypoparathyroidism — More likely
  • Calcium — Increased need
  • Vitamin K — Increased need
  • Spinal Arthritis — More likely
  • Myocarditis — More likely
  • Nephritis — More likely
  • ITGB3 (Mold Sensitivity) — Worse genetics
  • SOD3 (Oxidative Stress) — Worse
Running above the typical range  (23)
  • Aluminum — Higher levels, 83th percentile
  • HLA (Inflammation) — Higher activity, 80th percentile
  • CFH (Eye Health/ Longevity) — Higher activity
  • Fluoride Sensitivity — Higher
  • NQO1 (Detox) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
  • SUOX (PCOS/ Blood Sugar) — Higher activity
  • GC (Vitamin D) — Higher activity
  • MMP1 (Collagen) — Higher activity
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
  • PBDE Sensitivity (CYP2B6) — Higher
  • CYP1B1 (Detox/ Skin Health) — Higher activity
  • SULT1A1 (Detox) — Higher activity
  • GSTP1 (Detox) — Higher activity
  • Sulfation (Detox) — Higher activity
  • UGT (Detox) — Higher activity
  • CYP1A2 (Detox) — Higher activity
Running below the typical range  (18)
  • ADA (Cognition/Longevity) — Lower activity
  • CETP (Cholesterol/ Longevity) — Lower activity
  • SOD2 (Oxidative Stress) — Lower activity
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
  • CHIT1 (Mold Sensitivity) — Lower activity
  • GSTA1 (Detox/ Glutathione) — Lower activity
  • PAH Sensitivity — Lower
  • PON1 (Detox) — Lower activity
  • UGT2A1 (Cognition) — Lower activity
  • GCLC (Glutathione & Detox) — Lower activity
  • SLCO1B1 (Detox) — Lower activity
  • COQ2 (Oxidative Stress) — Lower activity
Working in your favour  (14)
  • Scoliosis — Less likely, 19th percentile
  • Tendon Inflammation — Less likely, 19th percentile
  • Optic Nerve Inflammation — Less likely, 19th percentile
  • Tendon Injury — Less likely, 18th percentile
  • Gut Inflammation — Less likely, 8th percentile
  • Appendicitis — Less likely, 8th percentile
  • Muscle Loss — Less likely
  • Lung Cancer — Less likely
  • IGF1R (Longevity) — Better
  • Ehlers-Danlos Syndrome (Progeroid — Less likely
  • ADAMTS5 (Joint Health) — Better genetics
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
In line with most people  (118)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Aging Eyes — Typical likelihood, 77th percentile
  • DNA Damage — Typical levels, 66th percentile
  • Alzheimer's Disease — Typical likelihood, 65th percentile
  • Bone Infection — Typical likelihood, 65th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Spinal Canal Narrowing — Typical likelihood, 60th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Gout — Typical likelihood, 58th percentile
  • Cadmium — Typical levels, 57th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Age-Related Macular Degeneration — Typical likelihood, 44th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Joint Stiffness — Typical likelihood, 39th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Fractures — Typical likelihood, 37th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tendon Lining Inflammation — Typical likelihood, 36th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Eczema — Typical likelihood, 29th percentile
  • Lead — Typical levels, 28th percentile
  • Organophosphate Sensitivity — Typical, 21th percentile
  • IL-6 — Typical levels, 20th percentile
  • Pesticide Sensitivity — Typical, 18th percentile
  • Arsenic — Typical levels, 16th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Facial Wrinkles — Typical
  • Longevity — Typical
  • Healthy Aging — Typical
  • Hair Graying — Typical
  • Pancreatic Cancer — Typical likelihood
  • SIRT1 (Longevity) — Typical activity
  • TERT (Longevity) — Typical activity
  • OBFC1 (Longevity) — Typical activity
  • AKT1 (Longevity) — Typical genetics
  • APOC3 (Blood Lipids/ Longevity) — Typical activity
  • FOXO3 (Longevity) — Typical activity
  • TAS2R16 (Bitter Taste/ Longevity) — Typical activity
  • PARP1 (Longevity, Cognition) — Typical genetics
  • Detox — Typical ability
  • Oxidative Stress — Typical
  • Benzene Sensitivity — Typical
  • NFE2L2/NRF2 (Detox) — Typical activity
  • Sensitivity to Airborne Mold — Typical
  • Sensitivity to Foodborne Mold — Typical
  • Multiple Chemical Sensitivity — Typical likelihood
  • BPA Sensitivity — Typical
  • Mercury — Typical levels
  • Phase I Detox — Typical ability
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL6 Gene (Inflammation) — Typical activity
  • Cold Intolerance — Typical likelihood
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • Hyperparathyroidism — Typical likelihood
  • Vitamin D — Typical need
  • Phosphate — Typical levels
  • Magnesium — Typical need
  • VDR (Vitamin D) — Typical activity
  • CYP2R1 (Vitamin D) — Typical activity
  • Psoriatic Arthritis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • COL5A1 (Collagen) — Typical activity
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • IgA Nephropathy — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics
  • Glyphosate Sensitivity — Typical
  • Air Pollution Sensitivity — Typical
  • Phthalate Sensitivity — Typical
  • GSDMB (Mold Sensitivity) — Typical activity
  • XPC (DNA Damage) — Typical activity
  • XRCC (DNA Damage) — Typical activity
  • Glutathione — Typical function
  • UGT1A1 (Detox) — Typical activity
  • AHR (Detox) — Typical activity
  • Phase II Detox — Typical ability
  • CYP1A1 (Detox) — Typical activity
  • NAT2 (Detox) — Intermediate
  • Lipid Oxidation — Typical
  • GPX4 (Selenium & Glutathione) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-4F289A
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-4F289A · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Longevity & Healthy Aging

Personalized Genetic Report
Longevity & Healthy AgingConditions Affecting LongevityLongevity MarkersLongevity Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-52007B
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-52007B
Panel
Longevity & Healthy Aging
Results scored
29 of 33
Need attention
5
Report
Summary Report

What this report covers

Longevity & Healthy Aging · Conditions Affecting Longevity · Longevity Markers · Longevity Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 29 results here, 5 came back worth discussing with a clinician and 4 came back in your favour. Bring this document to your appointment.

What this package looks at

Longevity & Healthy Aging — Longevity is a fascinating and complex area of study that encompasses not only the length of life but also the quality of life as we age. Genetic factors play a significant role in determining how long we live and how well we age.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Artery Hardening, Frailty, PPARD (Longevity), Prostate Cancer
relevance
2
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Colorectal Cancer, Artery Hardening, PPARD (Longevity), Prostate Cancer
relevance
3
Eat Fiber-Rich Foods

grams per day, spread out over all meals.

Relates to: Colorectal Cancer, Artery Hardening
relevance
4
Avoid Secondhand Smoke

Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Artery Hardening, Prostate Cancer
relevance
5
Walking30 minutes

Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.

Relates to: Artery Hardening, Colorectal Cancer, Frailty
relevance
6
Limit Trans Fats

Avoid fried foods, packaged snacks, baked goods, and fast foods, which are common sources of trans fats.

Relates to: Artery Hardening
relevance
7
Pomegranate Juice

Drink (about 240 milliliters) of 100% pomegranate juice daily, ideally in the morning to incorporate it into your daily routine.

Relates to: Colorectal Cancer, Artery Hardening, Prostate Cancer
relevance
8
Avoid Organochlorine Pesticide Exposure

Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.

Relates to: Colorectal Cancer, Artery Hardening, Prostate Cancer
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Green Tea
Relates to: Prostate Cancer, Artery Hardening, Colorectal Cancer
relevance
2
Omega-3 (Fish Oil)
Relates to: Artery Hardening, Prostate Cancer
relevance
3
Gotu Kola and Pycnogenol
Relates to: Artery Hardening
relevance
4
Psyllium
Relates to: Artery Hardening
relevance
5
Green Tea Extract
Relates to: Prostate Cancer, Artery Hardening
relevance
6
Maintain Optimal Vitamin D Levels
Relates to: Artery Hardening, Colorectal Cancer, Prostate Cancer, Frailty
relevance

Your headline findings

Of the 29 results in this package, these 5 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.

Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.

The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Eat Fiber-Rich Foods
    grams per day, spread out over all meals.
From your Longevity & Healthy Aging report
Prostate CancerMore likely
More likely to get prostate cancer based on 1,049,413 genetic variants we looked at
Your risk is greater than 94% of the population and lower than 6% of the population.

What this actually is

The exact cause of prostate cancer is not clearly understood, but several factors have been identified that increase the risk of developing this disease: Age: The risk increases significantly after age 50, and it is most common in men over 65.

Family history: Having a father or brother with prostate cancer more than doubles a man’s risk.

Race/Ethnicity: African-American men have a higher risk of prostate cancer than men of other races.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.

Ask your clinician about

  • Green Tea
  • Green Tea Extract

Named only. Marrow gives no dose and does not recommend these.

From your Longevity & Healthy Aging report
FrailtyMore likely
More likely to experience frailty based on 16,767 genetic variants we looked at
Your risk is greater than 89% of the population and lower than 11% of the population.

What this actually is

The clinical presentation of frailty includes symptoms such as fatigue, muscle weakness, slowed performance, and diminished energy reserves.

Due to its multidimensional nature, the diagnosis of frailty involves a comprehensive assessment of physical capability, nutritional status, and social and psychological functions.

Management strategies for frailty are typically multidisciplinary and can include tailored exercise programs to improve physical function, nutritional interventions to address potential deficiencies or undernutrition, and supportive measures to enhance social support and cognitive stimulation.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Longevity & Healthy Aging report
Colorectal CancerMore likely
More likely to get colorectal cancer based on 1,049,410 genetic variants we looked at
Your risk is greater than 73% of the population and lower than 27% of the population.

What this actually is

While the exact cause of colorectal cancer is not fully understood, several factors increase the risk of developing this disease: Age: The majority of cases occur in people aged 50 and older, though incidence rates are rising among younger populations.

Family history: Having a family history of colorectal cancer or polyps increases one's risk.

Personal history: Those with a history of inflammatory bowel disease (like Crohn's disease or ulcerative colitis), or who have had colorectal cancer or adenomatous polyps before are at higher risk.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Eat Fiber-Rich Foods
    grams per day, spread out over all meals.
  • Pomegranate Juice
    Drink (about 240 milliliters) of 100% pomegranate juice daily, ideally in the morning to incorporate it into your daily routine.
From your Longevity & Healthy Aging report
PPARD (Longevity)Worse
Higher predisposition than average

What this actually is

The rs2016520 was found to be exceptionally long Chinese people genotype is more above.

However, this Moreover, cholesterol and subjects.

For example, as using fats as the carbohydrates.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
From your Longevity & Healthy Aging report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.

About 60-70% of the differences in people’s cognitive decline may come from genetics.

For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].

From your Longevity & Healthy Aging report
Muscle LossLess likely
Less likely to have sarcopenia based on 10 genetic variants we looked at

What this actually is

About 60% of the differences in sarcopenia may be due to genetics.

Some genes associated with muscle growth, repair, and inflammation have been linked to sarcopenia susceptibility.

For example, genetically higher IGF-1 levels may be causally associated with higher muscle mass and a lower risk of muscle loss [R, R].

From your Longevity & Healthy Aging report
Lung CancerLess likely
Less likely to have lung cancer based on 849,819 genetic variants we looked at

What this actually is

Exposure to cigarette smoke is by far the main risk factor for lung cancer.

Other factors that may increase the risk include: Exposure to asbestos and other substances Exposure to radon Previous radiation therapy to the chest Family history Treatment for lung cancer usually begins with surgery to remove the tumor.

Treatment might start with chemotherapy and radiation instead depending on factors such as overall health, cancer type and stage, and preferences of the patient.

From your Longevity & Healthy Aging report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • CFH (Eye Health/ Longevity) — Higher activity
Running below the typical range  (2)
  • ADA (Cognition/Longevity) — Lower activity
  • CETP (Cholesterol/ Longevity) — Lower activity
Working in your favour  (1)
  • IGF1R (Longevity) — Better
In line with most people  (17)
  • Aging Eyes — Typical likelihood, 77th percentile
  • Alzheimer's Disease — Typical likelihood, 65th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Age-Related Macular Degeneration — Typical likelihood, 44th percentile
  • Facial Wrinkles — Typical
  • Longevity — Typical
  • Healthy Aging — Typical
  • Hair Graying — Typical
  • Pancreatic Cancer — Typical likelihood
  • SIRT1 (Longevity) — Typical activity
  • TERT (Longevity) — Typical activity
  • OBFC1 (Longevity) — Typical activity
  • AKT1 (Longevity) — Typical genetics
  • APOC3 (Blood Lipids/ Longevity) — Typical activity
  • FOXO3 (Longevity) — Typical activity
  • TAS2R16 (Bitter Taste/ Longevity) — Typical activity
  • PARP1 (Longevity, Cognition) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-52007B
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-52007B · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Mitochondrial Support

Personalized Genetic Report
Mitochondrial HealthDetox & Oxidative StressInflammationCold Exposure
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-C70CF2
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-C70CF2
Panel
Mitochondrial Support
Results scored
28
Need attention
2
Report
Summary Report

What this report covers

Mitochondrial Health · Detox & Oxidative Stress · Inflammation · Cold Exposure

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 28 results here, 2 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Mitochondrial Support — Think of mitochondria as tiny power plants inside each of your cells, converting the food you eat into energy that keeps you alive and thriving. But these remarkable cellular structures do much more than just produce energy -they're key players in your overall health and vitality.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Exposure to Molds

Keep indoor humidity levels below 50% by using dehumidifiers or air conditioners, ensure proper ventilation in areas like bathrooms and kitchens, fix leaks promptly, and clean up any water damage within 24-48 hours to prevent mold growth.

Relates to: Excessive Mast Cells
relevance
2
Avoid Exposure to Solvents

Wear protective gloves and masks when using solvent-based products such as paint thinners, degreasers, or nail polish removers.

Relates to: Excessive Mast Cells
relevance
3
Sunlight Exposure20 minutes

Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.

Relates to: Excessive Mast Cells
relevance
4
Avoid Exposure to Heavy Metals

Check for lead-based paints in older homes and avoid cooking or storing food in uncoated metal containers.

Relates to: Excessive Mast Cells
relevance
5
Low-Histamine Diet

Exclude high-histamine foods such as aged cheeses, smoked meats, fermented products like sauerkraut and kombucha, alcohol, and preserved foods. for at least 4 weeks to observe any improvements in symptoms.

Relates to: Excessive Mast Cells
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Quercetin
Relates to: Excessive Mast Cells
relevance
2
Rutin
Relates to: SOD2 (Oxidative Stress), Excessive Mast Cells
relevance
3
Manganese supplements
Relates to: SOD2 (Oxidative Stress)
relevance
4
Vitamin C
Relates to: Excessive Mast Cells
relevance
5
Dietary Omega-3 Fatty Acids
Relates to: Excessive Mast Cells
relevance
6
Turmeric
Relates to: Excessive Mast Cells
relevance
7
Maintain Optimal Vitamin D Levels
Relates to: Excessive Mast Cells
relevance

Your headline findings

Of the 28 results in this package, these 2 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.

These mutations are usually acquired during a person's life rather than being inherited.

Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.

Ask your clinician about

  • Quercetin
  • Rutin
  • Vitamin C

Named only. Marrow gives no dose and does not recommend these.

From your Mitochondrial Support report
Mitochondrial Health (Functional)Worse
Higher predisposition than average
From your Mitochondrial Support report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (4)
  • Fluoride Sensitivity — Higher
  • NQO1 (Detox) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
  • SUOX (PCOS/ Blood Sugar) — Higher activity
Running below the typical range  (1)
  • SOD2 (Oxidative Stress) — Lower activity
In line with most people  (21)
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Lead — Typical levels, 28th percentile
  • Pesticide Sensitivity — Typical, 18th percentile
  • Arsenic — Typical levels, 16th percentile
  • SIRT1 (Longevity) — Typical activity
  • Detox — Typical ability
  • Oxidative Stress — Typical
  • Benzene Sensitivity — Typical
  • NFE2L2/NRF2 (Detox) — Typical activity
  • Sensitivity to Airborne Mold — Typical
  • Sensitivity to Foodborne Mold — Typical
  • Multiple Chemical Sensitivity — Typical likelihood
  • BPA Sensitivity — Typical
  • Mercury — Typical levels
  • Phase I Detox — Typical ability
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL6 Gene (Inflammation) — Typical activity
  • Cold Intolerance — Typical likelihood
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • TNF Gene (Inflammation) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-C70CF2
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-C70CF2 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Bone Health

Personalized Genetic Report
Bone Health ProblemsBone Health Nutrients
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-13784A
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-13784A
Panel
Bone Health
Results scored
17
Need attention
4
Report
Summary Report

What this report covers

Bone Health Problems · Bone Health Nutrients

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 17 results here, 4 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.

What this package looks at

Bone Health — Bone health is crucial for maintaining a strong skeletal system, mobility, and overall physical well-being. While lifestyle factors such as diet and exercise play important roles in bone health, genetics also significantly influences how strong and resilient your bones are.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Broccoli

Incorporate at least one cup of chopped broccoli, either steamed or raw, into your daily diet.

Relates to: Calcium, Vitamin K
relevance
2
Collard Greens

Incorporate at least one cup of cooked or two cups of raw collard greens into your diet 3-4 times a week.

Relates to: Calcium, Vitamin K
relevance
3
Kale

Aim for a balanced diet consisting mostly of plant-based foods and lean protein sources, adjusting portions sizes to meet your individual nutritional needs and health goals.

Relates to: Calcium, Vitamin K
relevance
4
Salmon

Choose wild-caught salmon when possible for higher omega-3 content.

Relates to: Calcium, Hypoparathyroidism
relevance
5
Sardines

Incorporate two to three servings of sardines into your diet each week.

Relates to: Calcium, Hypoparathyroidism
relevance
6
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Bone Cancer
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Calcium, Hypoparathyroidism, Vitamin K
relevance
2
Dietary Calcium
Relates to: Hypoparathyroidism
relevance
3
Vitamin D and Calcium
Relates to: Calcium, Bone Cancer, Hypoparathyroidism
relevance
4
Magnesium
Relates to: Hypoparathyroidism
relevance
5
Dietary Omega-3 Fatty Acids
Relates to: Bone Cancer
relevance

Your headline findings

Of the 17 results in this package, these 4 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Bone CancerMore likely
More likely to have bone cancer based on 24,472 genetic variants we looked at

What this actually is

The exact causes of bone cancer are not well understood, but several factors can increase the risk: Genetic disorders: Certain inherited genetic disorders, such as hereditary retinoblastoma and Li-Fraumeni syndrome, are linked to a higher risk of bone cancer.

Previous radiation therapy: Exposure to high doses of radiation, such as those used in previous cancer treatments, can increase the risk.

Paget’s disease: This bone condition, mostly seen in elderly people, may increase the risk of developing osteosarcoma.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Ask your clinician about

  • Vitamin D and Calcium
  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
HypoparathyroidismMore likely
Higher predisposition than average

What this actually is

The condition can following surgical remove the Management of and vitamin D prevent symptoms.

Some patients may of their calcium quality of life. offers a more their use remains daily injections.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Dietary Calcium
  • Magnesium

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
CalciumIncreased need
Likely increased need for calcium based on 49,961 genetic variants we looked at

What this actually is

Key Takeaways: The amount of calcium in the blood at any given time is controlled by vitamin D and parathyroid hormone.

Much of the world's population is at risk for low calcium.

Beyond diet, it is important to maintain adequate vitamin D levels as well.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Maintain Optimal Vitamin D Levels
  • Vitamin D and Calcium

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report
Vitamin KIncreased need
Likely increased vitamin K need based on 11 genetic variants we looked at

What this actually is

Key Takeaways: Genes involved in higher or lower vitamin K levels may influence vitamin K breakdown, fat metabolism, and collagen and bone formation.

Having low vitamin K levels may contribute to bone health issues like osteoporosis.

is essential for blood clotting and bone health.

What you can do

  • Broccoli
    Incorporate at least one cup of chopped broccoli, either steamed or raw, into your daily diet.
  • Collard Greens
    Incorporate at least one cup of cooked or two cups of raw collard greens into your diet 3-4 times a week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Bone Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Bone SpursLess likely
Less likely to have bone spurs based on 1,676 genetic variants we looked at
Your risk is greater than 5% of the population and lower than 95% of the population.

What this actually is

Bone spurs develop as a result of bone and joint degeneration and are primarily associated with the aging process.

However, they can also arise from underlying diseases and conditions that affect bone and joint health: Osteoarthritis: The most common cause of bone spurs, osteoarthritis involves the breakdown of cartilage, leading to joint damage and increased bone friction.

Spinal degeneration: Bone spurs commonly occur in the spine as a result of the degeneration of discs and joints, often due to aging.

From your Bone Health report
ScoliosisLess likely
Less likely to have scolisosis based on 541,912 genetic variants we looked at
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

The impact of scoliosis on an individual can range from negligible to severe, potentially leading to discomfort, pain, and in some cases, respiratory and cardiovascular issues due to the distortion of the ribcage.

Treatment options depend on the severity and progression of the curve and can include observation, bracing, or surgical intervention.

Bracing is commonly used to prevent further progression of the curve in growing children and adolescents, while surgery may be reserved for more severe cases to correct and stabilize the spine.

From your Bone Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • GC (Vitamin D) — Higher activity
In line with most people  (10)
  • Bone Infection — Typical likelihood, 65th percentile
  • Spinal Canal Narrowing — Typical likelihood, 60th percentile
  • Fractures — Typical likelihood, 37th percentile
  • Osteoporosis — Typical likelihood, 33th percentile
  • Hyperparathyroidism — Typical likelihood
  • Vitamin D — Typical need
  • Phosphate — Typical levels
  • Magnesium — Typical need
  • VDR (Vitamin D) — Typical activity
  • CYP2R1 (Vitamin D) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-13784A
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-13784A · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Joint & Tendon Health

Personalized Genetic Report
Joint HealthTendon HealthJoint Health Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-5012AC
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-5012AC
Panel
Joint & Tendon Health
Results scored
27
Need attention
8
Report
Summary Report

What this report covers

Joint Health · Tendon Health · Joint Health Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 27 results here, 8 came back worth discussing with a clinician and 5 came back in your favour. Bring this document to your appointment.

What this package looks at

Joint & Tendon Health — Joint and tendon health is essential for maintaining mobility, flexibility, and overall physical function. Genetic factors play a significant role in determining your susceptibility to various conditions that affect the joints and tendons, such as joint pain, arthritis, and tendon problems. While

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Manual Therapy

Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
2
Physical Therapy30 minutes

Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ), Neck Arthritis
relevance
3
Shock Wave Therapy

Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.

Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement, Trigger Finger
relevance
4
Exercise Therapy

Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.

Relates to: Shoulder Impingement, Jaw Disorders (TMJ)
relevance
5
Reduce Jaw Strain

Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.

Relates to: Jaw Disorders (TMJ)
relevance
6
Low-Level Laser Therapy (LLLT)

Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Shoulder Impingement
relevance
7
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Heel Pain (Plantar Fasciitis), Jaw Disorders (TMJ), Neck Arthritis
relevance
8
Good Posture

Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.

Relates to: Shoulder Impingement, Heel Pain (Plantar Fasciitis), Disc Degeneration, Spinal Arthritis
relevance
9
Stretching15 minutes

Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.

Relates to: Heel Pain (Plantar Fasciitis), Dupuytren’s Contracture, Spinal Arthritis
relevance
10
Topical CBD

Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.

Relates to: Jaw Disorders (TMJ), Disc Degeneration, Neck Arthritis, Spinal Arthritis
relevance
11
Myofascial Release

Incorporate myofascial release into your routine by using tools like foam rollers or massage balls, focusing on TA tense areas for about 5-20 minutes daily.

Relates to: Heel Pain (Plantar Fasciitis)
relevance
12
Apply Heat15 minutes

Do this TA several times a day, ensuring there's at least a 1-hour interval between sessions to avoid skin damage.

Relates to: Jaw Disorders (TMJ), Neck Arthritis, Spinal Arthritis
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Methylsulfonylmethane (MSM)
Relates to: Jaw Disorders (TMJ), Heel Pain (Plantar Fasciitis), Shoulder Impingement
relevance
2
Vitamin C
Relates to: Heel Pain (Plantar Fasciitis), Shoulder Impingement
relevance

Your headline findings

Of the 27 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Heel Pain (Plantar Fasciitis)More likely
More likely to have plantar fasciitis based on 28,598 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Factors that might increase the risk of developing plantar fasciitis include: Age, with it being most common between the ages of 40 and 60 Certain types of exercise, such as long-distance running or ballet dancing Foot mechanics, including having a high arch, flat feet, or an abnormal walking pattern Obesity, which places extra stress on the plantar fascia Occupations that require long periods of standing or walking on hard surfaces Wearing shoes with inadequate support Genetics While plantar fasciitis is primarily associated with environmental factors and physical stress on the foot, there is some evidence to suggest that genetic factors might play a role in predisposing certain individuals to the condition.

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
From your Joint & Tendon Health report
Neck ArthritisMore likely
Higher predisposition than 98% of people
Your result sits higher than 98% of the population.

What this actually is

As the disks in the cervical spine dehydrate and shrink, signs of osteoarthritis develop, including the formation of bony projections along the edges of bones (bone spurs).

Cervical spondylosis can sometimes lead to a narrowing of the space needed by the spinal cord and the nerve roots that pass through the spine to the rest of the body.

More likely to have When these nerve pathways are affected, individuals might 481,932 genetic experience neurological symptoms such as numbness, weakness, or tingling in the arms, hands, legs, or feet.

What you can do

  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Acupuncture
    Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Shoulder ImpingementMore likely
More likely to have shoulder impingement based on 1,676 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

Risk factors for shoulder impingement include: Age: It is more common in middle-aged and older adults due to wear and tear.

Activities: Overhead activities common in some sports and jobs can lead to impingement.

Trauma: A fall or blow to the shoulder can initiate impingement symptoms.

What you can do

  • Manual Therapy
    Reduce Tendon Strain To reduce tendon strain, modify your daily activities to avoid motions that cause discomfort or pain.
  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Exercise Therapy
    Begin by consulting with a physical therapist to assess your condition and create a personalized exercise plan.
From your Joint & Tendon Health report
Disc DegenerationMore likely
More likely to have disc degeneration based on 844,435 genetic variants we looked at
Your risk is greater than 90% of the population and lower than 10% of the population.

What this actually is

As disc degeneration progresses, individuals may experience chronic back pain, stiffness, or reduced mobility.

In some cases, the narrowing of the disc space can lead to nerve compression, resulting in symptoms such as sciatica, which is characterized by radiating pain down one or both legs.

Moreover, the body may form bony growths called bone spurs in response to the instability, potentially exacerbating nerve compression and leading to further discomfort and disability.

What you can do

  • Good Posture
    Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report
Trigger FingerMore likely
More likely to have trigger finger based on 3 genetic variants we looked at
Your risk is greater than 87% of the population and lower than 13% of the population.

What this actually is

Risk factors for trigger finger include [R, R, R, R, R]: Hobbies or jobs that require repetitive hand motions or prolonged gripping Some chronic health conditions (e.g., diabetes, rheumatoid arthritis) Female sex Previous surgery for carpal tunnel syndrome Genetics The genes involved in this condition may alter the structure of tendons [R, R].

What you can do

  • Shock Wave Therapy
    Schedule and attend sessions for extracorporeal shock wave therapy (ESWT) with a qualified healthcare provider.
From your Joint & Tendon Health report
Jaw Disorders (TMJ)More likely
More likely to have a TMJ disorder based on 17,327 genetic variants we looked at
Your risk is greater than 81% of the population and lower than 19% of the population.

What this actually is

Key Takeaways: Genetics plays a role in factors that contribute to TMJ disorders, such as arthritis or teeth grinding.

These genes may affect bone and cartilage structure, and mental health.

Factors that may increase the risk of developing TMJ disorders include arthritis, jaw injury, teeth grinding or clenching, and connective tissue problems.

What you can do

  • Reduce Jaw Strain
    Avoid chewing gum, biting on hard foods like nuts or ice, and lengthy yawning.
  • Physical Therapy 30 minutes
    Attend physical therapy sessions 2-3 times per week for a duration of 4-6 weeks, depending on your specific TA condition and the advice of your healthcare provider.
  • Low-Level Laser Therapy (LLLT)
    Use a low-level laser therapy device, as directed by its manual or a healthcare professional, on the affected area.
From your Joint & Tendon Health report
Dupuytren’s ContractureMore likely
More likely to have a Dupuytren's contracture based on 311 genetic variants we looked at
Your risk is greater than 80% of the population and lower than 20% of the population.

What this actually is

This condition commonly occurs in older adults, and risk factors include Northern European ancestry, a family history of the condition, diabetes, and smoking.

Although pain is not always associated with Dupuytren’s contracture, the limitation in hand function and dexterity can significantly interfere with daily activities.

Treatment can range from observation to various invasive procedures, such as needle aponeurotomy, enzyme injections to break down the tissue cord, or in severe cases, surgical removal of the affected tissue.

What you can do

  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
  • Avoid Strenuous Activity
    Refrain from participating in high-intensity physical activities such as running, heavy weightlifting, and high-impact sports.
From your Joint & Tendon Health report
Spinal ArthritisMore likely
More likely to have spinal arthritis based on 977,839 genetic variants we looked at

What this actually is

The symptoms of spinal arthritis might progress gradually and can vary in severity.

Individuals with this condition often experience chronic low back or neck pain which can sometimes be accompanied by a grinding sensation or a feeling of bone-on-bone friction.

As the disease advances, it can lead to the development of bone spurs or osteophytes, which may impinge on nerve roots, potentially causing tingling, numbness, or weakness in the limbs.

What you can do

  • Good Posture
    Do this continuously throughout the day, reminding yourself to adjust your posture whenever you notice it lapsing.
  • Stretching 15 minutes
    Incorporate stretching exercises into your daily routine, dedicating at least 10-15 minutes each day.
  • Topical CBD
    Apply a CBD-infused cream or ointment to the affected area of the skin 2-3 times per day, gently massaging it into the skin until fully absorbed.
From your Joint & Tendon Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Joint PainLess likely
Less likely to have osteoarthritis based on 385,825 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Key Takeaways: Osteoarthritis will affect the majority of people over the age of 55.

So, even with low genetic risk, the overall risk is still high for older people.

About 50% of the differences in people's chances of getting osteoarthritis may be due to genetics.

From your Joint & Tendon Health report
Tendon InjuryLess likely
Less likely to have tendinopathy based on 6 genetic variants we looked at
Your risk is greater than 18% of the population and lower than 82% of the population.

What this actually is

Other risk factors include intense physical activity or certain sports, using improper training technique or equipment, doing repetitive tasks, age (over 40), being female, some chronic health conditions and medications.

About 16 million tendon and ligament injuries occur in the U.S. each year.

If you have a high genetic risk, you may lower your overall risk by taking action on those factors that you can change.

From your Joint & Tendon Health report
Tendon InflammationLess likely
Less likely to have tendon inflammation based on 1,657 genetic variants we looked at
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Potential risk factors for tendon inflammation include: Age: Tendinitis is more common as tendons become less flexible with age.

Occupations that involve repetitive motions or forceful exertion.

Certain sports, particularly those that involve repetitive movements.

From your Joint & Tendon Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • MMP1 (Collagen) — Higher activity
Working in your favour  (2)
  • Ehlers-Danlos Syndrome (Progeroid — Less likely
  • ADAMTS5 (Joint Health) — Better genetics
In line with most people  (13)
  • Achilles Tendon Injury — Typical likelihood, 79th percentile
  • Hip Pain — Typical likelihood, 64th percentile
  • Gout — Typical likelihood, 58th percentile
  • Carpal Tunnel Syndrome — Typical likelihood, 56th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • Joint Stiffness — Typical likelihood, 39th percentile
  • Knee Pain — Typical likelihood, 36th percentile
  • Tendon Lining Inflammation — Typical likelihood, 36th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Psoriatic Arthritis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • COL5A1 (Collagen) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-5012AC
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-5012AC · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Inflammation & Autoimmunity

Personalized Genetic Report
Inflammatory Gut ConditionsOther Inflammatory ConditionsAutoimmune Joint ConditionsAutoimmune Skin ConditionsOther Autoimmune ConditionsInflammation MarkersHLA GenesOther Inflammation Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-0FCD26
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-0FCD26
Panel
Inflammation & Autoimmunity
Results scored
80 of 83
Need attention
9
Report
Summary Report

What this report covers

Inflammatory Gut Conditions · Other Inflammatory Conditions · Autoimmune Joint Conditions · Autoimmune Skin Conditions · Other Autoimmune Conditions · Inflammation Markers · HLA Genes · Other Inflammation Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 80 results here, 9 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Inflammation & Autoimmunity — Inflammation and autoimmunity are key processes that affect the body’s ability to maintain health and respond to threats. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to a variety of health problems, from gut issues to systemic diseases.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Pancreas Inflammation, Eye Inflammation, Myocarditis
relevance
2
Yoga30 minutes

Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Relates to: Crohn’s Disease, Pancreas Inflammation, Eye Inflammation, Psoriasis
relevance
3
Dietary Antioxidants

Avoid Cannabis Stop any form of cannabis use, including smoking, vaping, edibles, and topical applications.

Relates to: Pancreas Inflammation, Psoriasis, Myocarditis, Crohn’s Disease
relevance
4
Acupuncture

Visit a licensed acupuncturist for a session, typically lasting between 30 to 60 minutes, once or twice a week.

Relates to: Pancreas Inflammation, Eye Inflammation
relevance
5
Antioxidant Supplements
Relates to: Pancreas Inflammation
relevance
6
Pancreatic Enzymes

based on the degree of pancreatic insufficiency and the fat content of the meal.

Relates to: Pancreas Inflammation, Psoriasis
relevance
7
Avoid Refined Sugar

Replace them with natural sugars found in fruits and whole grains.

Relates to: Crohn’s Disease, Myocarditis, Pancreas Inflammation
relevance
8
Autoimmune Protocol (AIP) Diet

Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Relates to: Crohn’s Disease, Eye Inflammation, Thyroid Inflammation
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Maintain Optimal Vitamin D Levels
Relates to: Crohn’s Disease, Thyroid Inflammation, HLA-DOB (Inflammation), Psoriasis
relevance
2
Omega-3 (Fish Oil)
Relates to: SH2B3 (Autoimmunity), Crohn’s Disease, Pancreas Inflammation, Psoriasis
relevance
3
Dietary Omega-3 Fatty Acids
Relates to: Crohn’s Disease, Myocarditis, Nephritis, Pancreas Inflammation
relevance
4
Probiotics
Relates to: Pancreas Inflammation, SH2B3 (Autoimmunity), Crohn’s Disease, NLRP3 (Gut Inflammation)
relevance
5
Curcumin
Relates to: NLRP3 (Gut Inflammation), Crohn’s Disease, Psoriasis, Eye Inflammation
relevance
6
Boswellia
Relates to: Crohn’s Disease
relevance

Your headline findings

Of the 80 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Tonsil InflammationMore likely
Higher predisposition than 99% of people
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

The course of cause is viral or require specific through pain Bacterial can require Recurrent cases of recommendation for of the tonsils. are also common cause.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Thyroid InflammationMore likely
More likely to have thyroid inflammation based on 348,866 genetic variants we looked at
Your risk is greater than 96% of the population and lower than 4% of the population.

What this actually is

The most common forms of thyroiditis include Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid; postpartum thyroiditis, which can occur after childbirth; and subacute thyroiditis, which usually follows a viral infection.

Diagnosis may involve blood tests to measure thyroid hormone levels, as well as antibody tests to detect autoimmune activity.

Treatment depends on the type and severity of thyroiditis, ranging from observation and symptom management to medications like levothyroxine for hypothyroidism or beta-blockers for hyperthyroidism symptoms.

What you can do

  • Autoimmune Protocol (AIP) Diet
    Eliminate grains, legumes, nuts, seeds, nightshades, dairy, eggs, coffee, alcohol, refined sugars, refined oils, food additives, and processed foods from your diet for a minimum of 30 days.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Pancreas InflammationMore likely
More likely to get pancreas inflammation based on 1,669 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

The pancreas is an organ located behind the stomach that releases crucial enzymes for carbs and fats digestion.

Pancreatitis is inflammation of the pancreas, which can be acute or chronic.

Potential risk factors for pancreatitis include [R, R, R]: Alcohol Cigarette smoking Obesity High blood lipids Certain medications Genetics Genetically predicted higher fasting insulin may be associated with acute and chronic pancreas inflammation.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Probiotics
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Urethra InflammationMore likely
More likely to have non-specific urethritis based infections
Your risk is greater than 88% of the population and lower than 12% of the population.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Eye InflammationMore likely
More likely to have uveitis based on 3,409 genetic variants we looked at
Your risk is greater than 84% of the population and lower than 16% of the population.

What this actually is

The management of uveitis involves addressing both the inflammation and the underlying cause if identified.

Typical treatments include corticosteroids to reduce the inflammation and drugs that manage the immune system's response.

Careful monitoring by an ophthalmologist is critical to prevent complications such as glaucoma, cataracts, and macular edema, all of which could lead to loss of vision.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
Crohn’s DiseaseMore likely
More likely to get Crohn's disease based on 1,031,499 genetic variants we looked at
Your risk is greater than 66% of the population and lower than 34% of the population.

What this actually is

Aside from gastrointestinal symptoms, Crohn's Disease can also have systemic effects on the body, leading to issues such as anemia, skin rashes, arthritis, and eye inflammation.

The cause of Crohn's Disease is not fully understood, but it involves an abnormal immune response to the microorganisms in the intestine, in genetically susceptible individuals.

There's no known cure for Crohn's Disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission and healing of inflammation.

What you can do

  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Dietary Omega-3 Fatty Acids

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
PsoriasisMore likely
More likely to have psoriasis based on 1,049,035 genetic variants we looked at
Your risk is greater than 65% of the population and lower than 35% of the population.

What this actually is

triggers include: infections, weather, skin injuries, stress, cigarette smoke, alcohol abuse, steroid withdrawal.

About 2% of Americans have psoriasis, mostly appearing in younger and older adults.

Even though the condition is rare, people with high genetic risk should understand and be wary of potential triggers.

What you can do

  • Pancreatic Enzymes
    based on the degree of pancreatic insufficiency and the fat content of the meal.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels
  • Omega-3 (Fish Oil)

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
MyocarditisMore likely
Higher predisposition than average

What this actually is

Myocarditis can be Viral parvovirus, and Bacterial Parasitic cruzi and Autoimmune Exposure to certain Allergic There is some myocarditis, associated with might influence how and other triggers Preventing avoiding avoiding toxic identify early symptoms of a palpitations.

What you can do

  • Whole-Food Plant-Based Diet
    few weeks to avoid digestive discomfort.

Ask your clinician about

  • Potassium
  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Inflammation & Autoimmunity report
A further 1 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Gut InflammationLess likely
Less likely to have IBD based on 1,671 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Risk factors include being under age 30, European ancestry, and smoking.

IBD may cause: diarrhea, fatigue, abdominal pain, bloody stool, weight loss, inflammation, liver damage, and colon cancer.

IBD only affects about 3 in 1000 people worldwide.

From your Inflammation & Autoimmunity report
AppendicitisLess likely
Less likely to have appendicitis based on 809,853 genetic variants we looked at
Your risk is greater than 8% of the population and lower than 92% of the population.

What this actually is

Other risk factors include being young and male.

is not rare, happening to about 7-8% of people in their lifetime.

If your genetic risk is high, know the symptoms and seek medical attention if you have them.

From your Inflammation & Autoimmunity report
Optic Nerve InflammationLess likely
Lower predisposition than 81% of people
Your risk is greater than 19% of the population and lower than 81% of the population.

What this actually is

Optic Nerve The causes of optic to autoimmune neuromyelitis indication of MS in infections can Recovery from optic weeks in most few months, some permanent vision corticosteroids to recovery of vision, among individuals.

From your Inflammation & Autoimmunity report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (1)
  • Nephritis — More likely
Running above the typical range  (8)
  • HLA (Inflammation) — Higher activity, 80th percentile
  • Basophils — Higher levels
  • HLA-DOB (Inflammation) — Higher activity
  • NF-kB (Inflammation) — Higher activity
  • NLRP3 (Gut Inflammation) — Higher activity
  • ANKRD55 (Autoimmune) — Higher activity
  • ABCB1 (Chronic Lyme) — Higher activity
  • HNMT (Histamine) — Higher activity
Running below the typical range  (7)
  • SH2B3 (Autoimmunity) — Lower activity
  • HNF4A (Gut Inflammation) — Lower activity
  • CTLA4 (Autoimmunity) — Lower activity
  • IL1B (Inflammation/ Fatigue) — Lower activity
  • JAK2 (Gut Inflammation) — Lower activity
  • IL8 (Inflammation) — Lower activity
  • IL21 (Autoimmunity & Allergies) — Lower activity
Working in your favour  (3)
  • Diverticular Disease — Less likely
  • Sjogren's Syndrome — Less likely
  • IL6R (Weight) — Better genetics
In line with most people  (50)
  • Ulcerative Colitis — Typical likelihood, 63th percentile
  • Multiple Sclerosis — Typical likelihood, 60th percentile
  • Stomach Inflammation — Typical likelihood, 42th percentile
  • Celiac Disease — Typical likelihood, 42th percentile
  • Rheumatoid Arthritis — Typical likelihood, 40th percentile
  • HRH4 (Allergies, Inflammation) — Typical activity, 39th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Eczema — Typical likelihood, 29th percentile
  • IL-6 — Typical levels, 20th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Lupus — Typical likelihood, 12th percentile
  • Chronic Lyme — Typical likelihood
  • Sepsis — Typical likelihood
  • Pulmonary Fibrosis — Typical likelihood
  • Actinic Keratosis — Typical likelihood
  • Meningitis — Typical likelihood
  • Sarcoidosis — Typical likelihood
  • Rheumatic Fever — Typical likelihood
  • Psoriatic Arthritis — Typical likelihood
  • Ankylosing Spondylitis — Typical likelihood
  • Vitiligo — Typical likelihood
  • Alopecia Areata — Typical likelihood
  • Systemic Sclerosis — Typical likelihood
  • Pemphigus Vulgaris — Typical likelihood
  • Behcet’s Disease — Typical likelihood
  • IgA Nephropathy — Typical likelihood
  • TNF — Typical levels
  • White Blood Cells — Typical levels
  • Eosinophils — Typical levels
  • Monocytes — Typical levels
  • Neutrophils — Typical levels
  • Erythrocyte Sedimentation Rate — Typical levels
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL-17 (Th17) — Typical levels
  • HLA-B (Autoimmune) — Typical
  • HLA-DQ (Inflammation) — Typical activity
  • HLA-DRB1 (Autoimmunity) — Typical
  • HLA-DQA2 (Inflammation) — Typical
  • TLR4 (Inflammation) — Typical activity
  • PTPN22 (Autoimmunity) — Typical
  • DAO (Histamine) — Typical activity
  • STAT3 (Th1/Th17) — Typical activity
  • TNF Gene (Inflammation) — Typical activity
  • IL13 (Allergies, Lung Function) — Typical activity
  • IL4 (Allergies, Autoimmunity) — Typical activity
  • CRP Gene — Typical activity
  • PADI4 (Autoimmune) — Typical activity
  • IL10 Gene (Autoimmunity) — Typical activity
  • SLC22A4 (Gut Inflammation) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-0FCD26
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-0FCD26 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Toxins & Detox

Personalized Genetic Report
PesticidesHeavy MetalsAir PollutionPlasticsMoldOther PollutantsDetoxOxidative Stress
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-257C21
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-257C21
Panel
Toxins & Detox
Results scored
51 of 58
Need attention
2
Report
Summary Report

What this report covers

Pesticides · Heavy Metals · Air Pollution · Plastics · Mold · Other Pollutants · Detox · Oxidative Stress

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 51 results here, 2 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Toxins & Detox — The impact of environmental toxins on health is an increasingly important topic in personalized health and functional medicine. Our genetic makeup plays a significant role in how our bodies process, detoxify, and respond to various toxins.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Dietary Antioxidants

In line with this, a higher intake of antioxidants may support a longer life.

Relates to: SOD3 (Oxidative Stress), Aluminum
relevance
2
Dietary Copper

Include servings of shellfish, whole grains, nuts, seeds, potatoes, and dark leafy greens.

Relates to: SOD3 (Oxidative Stress)
relevance
3
Dietary Polyphenols

achieve a beneficial intake of polyphenols.

Relates to: Aluminum
relevance
4
Avoid Aluminum Exposure

Use aluminum-free deodorants and avoid cooking or storing food in aluminum foil or aluminum cookware.

Relates to: Aluminum
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Glutathione supplements
Relates to: UGT2A1 (Cognition)
relevance
2
N-acetylcysteine (NAC)
Relates to: UGT2A1 (Cognition), Aluminum
relevance
3
Curcumin
Relates to: SOD2 (Oxidative Stress)
relevance
4
Vitamin C
Relates to: Aluminum
relevance
5
Selenium Supplements
Relates to: Aluminum
relevance
6
Zinc
Relates to: Aluminum
relevance
7
Vitamin E
Relates to: Aluminum
relevance
8
Magnesium
Relates to: Aluminum
relevance
9
Green Tea
Relates to: Aluminum
relevance

Your headline findings

Of the 51 results in this package, these 2 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

ITGB3 (Mold Sensitivity)Worse genetics
Likely worse ITGB3 genetics based on 11 genetic variants we looked at

What this actually is

A study of 1243 participants associated the ‘A’ allele of rs2056131 with a decreased sensitization to molds in people with asthma.

From your Toxins & Detox report
SOD3 (Oxidative Stress)Worse
Higher predisposition than average

What this actually is

SOD3 (Oxidative The only human lifespan death in a group of people with the with the ‘AG’ slightly longer difference in age year and a half The risk ‘A’ conditions [R, R]: High Type 2 diabetes However, ‘G’ is the The connection speculative at this between variants at search for a human fact, at least one correlation at all That said, there’s studies on variants up a direct influence: Risk of dying Lung injury and Stroke in women Among them, ‘G’ allele times, but reduces variant has been cardiovascular Furthermore, low polyneuropathy in These are all search goes on for lifespan.

What you can do

  • Dietary Antioxidants
    In line with this, a higher intake of antioxidants may support a longer life.
  • Dietary Copper
    Include servings of shellfish, whole grains, nuts, seeds, potatoes, and dark leafy greens.
  • Dietary Copper
    Include servings of shellfish, whole grains, nuts, seeds, potatoes, and dark leafy greens.
From your Toxins & Detox report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (10)
  • Aluminum — Higher levels, 83th percentile
  • PBDE Sensitivity (CYP2B6) — Higher
  • CYP1B1 (Detox/ Skin Health) — Higher activity
  • SULT1A1 (Detox) — Higher activity
  • NQO1 (Detox) — Higher activity
  • GSTP1 (Detox) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
  • Sulfation (Detox) — Higher activity
  • UGT (Detox) — Higher activity
  • CYP1A2 (Detox) — Higher activity
Running below the typical range  (9)
  • CHIT1 (Mold Sensitivity) — Lower activity
  • GSTA1 (Detox/ Glutathione) — Lower activity
  • PAH Sensitivity — Lower
  • PON1 (Detox) — Lower activity
  • UGT2A1 (Cognition) — Lower activity
  • GCLC (Glutathione & Detox) — Lower activity
  • SLCO1B1 (Detox) — Lower activity
  • COQ2 (Oxidative Stress) — Lower activity
  • SOD2 (Oxidative Stress) — Lower activity
In line with most people  (30)
  • DNA Damage — Typical levels, 66th percentile
  • Cadmium — Typical levels, 57th percentile
  • Lead — Typical levels, 28th percentile
  • Organophosphate Sensitivity — Typical, 21th percentile
  • Pesticide Sensitivity — Typical, 18th percentile
  • Arsenic — Typical levels, 16th percentile
  • Glyphosate Sensitivity — Typical
  • Mercury — Typical levels
  • Air Pollution Sensitivity — Typical
  • BPA Sensitivity — Typical
  • Phthalate Sensitivity — Typical
  • Sensitivity to Airborne Mold — Typical
  • Sensitivity to Foodborne Mold — Typical
  • GSDMB (Mold Sensitivity) — Typical activity
  • XPC (DNA Damage) — Typical activity
  • XRCC (DNA Damage) — Typical activity
  • Benzene Sensitivity — Typical
  • Multiple Chemical Sensitivity — Typical likelihood
  • Detox — Typical ability
  • Glutathione — Typical function
  • UGT1A1 (Detox) — Typical activity
  • AHR (Detox) — Typical activity
  • NFE2L2/NRF2 (Detox) — Typical activity
  • Phase I Detox — Typical ability
  • Phase II Detox — Typical ability
  • CYP1A1 (Detox) — Typical activity
  • NAT2 (Detox) — Intermediate
  • Oxidative Stress — Typical
  • Lipid Oxidation — Typical
  • GPX4 (Selenium & Glutathione) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-257C21
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-257C21 · © 2026 Marrow Health.