Marrow
Genomics · Genetic Reports · Precision Wellness

Metabolic Health Package

Personalized 4-Report Genetic Package
Metabolic HealthBlood Sugar ControlWeight & Body FatMitochondrial Support
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-04D34E
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-04D34E
Reports in package
4
Results scored
109 of 160
Need attention
9
Report
Summary Report

The reports inside this package

This one document contains 4 complete genetic reports. Each was scored on its own, then combined here so you can read everything in one place. Every result further down is labelled with the report it came from.

Metabolic Health58 results reported of 61 analytes · 50 recommendations
Blood Sugar Control35 results reported of 38 analytes · 50 recommendations
Weight & Body Fat33 results reported of 33 analytes · 50 recommendations
Mitochondrial Support28 results reported of 28 analytes · 50 recommendations

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 109 results here, 9 came back worth discussing with a clinician and 7 came back in your favour. Bring this document to your appointment.

What this package looks at

Metabolic Health — Is your metabolism optimal? Maybe, but probably not. A recent study indicated that only about 1 in 8 people in the U.S. have optimal metabolic health [R].

Blood Sugar Control — Blood sugar control is essential for maintaining energy levels, supporting metabolic health, and preventing long-term complications. Genetic predispositions can significantly influence how well your body regulates blood sugar. These genetic factors may affect insulin sensitivity, glucose

Weight & Body Fat — Weight management and body fat distribution are influenced by a combination of environmental factors, lifestyle choices, and genetics. Genetic predispositions can significantly affect your tendency to gain or lose weight, how your body stores fat, and how efficiently your

Mitochondrial Support — Think of mitochondria as tiny power plants inside each of your cells, converting the food you eat into energy that keeps you alive and thriving. But these remarkable cellular structures do much more than just produce energy -they're key players in your overall health and vitality.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: ADRB2 (Weight), Visceral Fat, Diabetic Neuropathy
relevance
2
Limit Calorie Intake

Consume fewer calories than your body needs for maintenance.

Relates to: UCP1 (Weight), Visceral Fat
relevance
3
Avoid Sugary Foods & Drinks

Aim to do this daily for ongoing health benefits.

Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
4
Intermittent Fasting

Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.

Relates to: ADRB2 (Weight), Visceral Fat
relevance
5
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: TCF7L2 (Blood Sugar/Diet), Visceral Fat
relevance
6
High-Intensity Interval Training (HIIT)30 minutes

Engage in HIIT workouts for at least 30 minutes per session, 3 times a week.

Relates to: Visceral Fat
relevance
7
Keto Diet

Adopt a diet that consists of about 70-80% fat, 10-20% protein, and 5-10% carbohydrates.

Relates to: Visceral Fat
relevance
8
Regular Sleep Schedule

Aim for 7-9 hours of sleep per night.

Relates to: Visceral Fat, Low Blood Sugar
relevance
9
Whole Grains

Aim to replace refined grains with whole grains at each meal for optimal benefits.

Relates to: TCF7L2 (Blood Sugar/Diet), Visceral Fat
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Berberine
Relates to: FOXO1 (Blood Sugar), TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
2
Zinc
Relates to: SLC30A8 (Blood Sugar), Diabetic Foot Ulcers
relevance
3
Probiotics
Relates to: Visceral Fat
relevance
4
Balance Iodine Intake
Relates to: Visceral Fat
relevance
5
Quercetin
Relates to: Excessive Mast Cells
relevance

Your headline findings

Of the 109 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Low Blood SugarMore likely
More likely to have low blood sugar based on 126,569 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Other non-diabetic risk factors include age, drinking alcohol, certain medications, severe infections, problems with your adrenal or pituitary gland, liver, kidney, or pancreas.

Other diabetic risk factors include taking too much diabetes medication, not eating enough or skipping meals, increasing physical activity without adjusting diet or medications, and drinking alcohol.

If you have high genetic risk, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Regular Sleep Schedule
    Aim for 7-9 hours of sleep per night.
  • Honey
    Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.
From your Metabolic Health report & Blood Sugar Control
Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.

These mutations are usually acquired during a person's life rather than being inherited.

Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.

Ask your clinician about

  • Quercetin
  • Maintain Optimal Vitamin D Levels
  • Rutin

Named only. Marrow gives no dose and does not recommend these.

From your Mitochondrial Support report
Heavy SweatingMore likely
More likely to have hyperhidrosis based on 104 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.

What this actually is

Key Takeaways: Genes that affect excessive sweating may influence nerve function and chemical messengers.

Excessive sweating can impact quality of life and cause undue stress and anxiety.

If you have symptoms, you may want to consult your doctor to rule out other conditions.

From your Metabolic Health report
ADRB2 (Weight)Worse genetics
Higher predisposition than average

What this actually is

The rs1042714 variant (also known as Q27E or Gln27Glu) has been most widely researched when it comes to weight.

Its minor ‘G’ allele (Glu, E) was associated with approximately 20% higher odds of obesity in a meta-analysis of 18 studies.

An older meta-analysis came to a similar conclusion.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Intermittent Fasting
    Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.

Ask your clinician about

  • Caffeine

Named only. Marrow gives no dose and does not recommend these.

From your Metabolic Health report & Weight & Body Fat
TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average

What this actually is

The two main TCF7L2 variants are rs7903146 and rs12255372.

They are almost always inherited together, which means they act as a single genetic factor.

Their "T" alleles have one of the strongest known links with type 2 diabetes.

What you can do

  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.
  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.
  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
From your Metabolic Health report & Blood Sugar Control
Diabetic NeuropathyMore likely
More likely to have diabetic neuropathy based on 1,658 genetic variants we looked at

What this actually is

Prolonged exposure to high blood sugar levels is the primary cause of diabetic neuropathy.

However, other factors that might increase the risk or severity of diabetic neuropathy include: Smoking Alcohol abuse Obesity High blood pressure Kidney disease Genetics Specific genetic variations might render some individuals more vulnerable to the neurotoxic effects of high blood sugar.

Hence, while some people with diabetes may never develop neuropathy, others might face complications even with good glucose control.

Ask your clinician about

  • Alpha-Lipoic Acid
  • Tocotrienols
  • Coenzyme Q10 (CoQ10)

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
Diabetic Foot UlcersMore likely
Higher predisposition than average

What this actually is

The following factors may increase the risk of diabetic foot ulcers: Peripheral neuropathy, which reduces the ability to feel pain and detect injuries.

Poor blood circulation, which compromises skin health and healing ability.

Foot deformities, which increase the risk of pressure sores.

What you can do

  • Infrared Light Therapy
    After one month, the patients’ ulcers shrank in size and had fewer secretions.
  • Honey
    Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
Diabetic NephropathyMore likely
More likely to have diabetic nephropathy based on 28,985 genetic variants we looked at

What this actually is

Factors linked to an increased risk of diabetic nephropathy include: Poorly controlled blood sugar levels High blood pressure Long duration of diabetes Smoking Obesity Family history of kidney disease High cholesterol levels Managing diabetic nephropathy involves controlling blood sugar and blood pressure, alongside lifestyle changes.

Common treatments include: Medications: ACE inhibitors or ARBs to control blood pressure, blood sugar-lowering drugs, and statins for cholesterol management.

Dietary changes: Low-protein and low-sodium diets to reduce kidney strain.

What you can do

  • Okra
  • Avoid Organochlorine Pesticide Exposure
    Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.

Ask your clinician about

  • Resveratrol

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
A further 1 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.

Weight gain affects conditions like high blood sugar and heart disease.

However, it is highly modifiable by diet and exercise.

From your Metabolic Health report & Weight & Body Fat
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Metabolic Health report & Blood Sugar Control, Weight & Body Fat
Sugar CravingsLess likely
Less likely to crave sugar based on 673,476 genetic variants we looked at
Your risk is greater than 20% of the population and lower than 80% of the population.

What this actually is

People who have less sensitive sweet receptors may have a “sweet tooth.” They may prefer sweet foods and eat more of them [R, R, R].

From your Blood Sugar Control report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Worth a conversation with your doctor  (1)
  • Mitochondrial Health (Functional) — Worse
Running above the typical range  (13)
  • IRS1 (Metabolic Health) — Higher activity, 85th percentile
  • Visceral Fat — Higher levels, 82th percentile
  • FOXO1 (Blood Sugar) — Higher activity
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
  • DIO1 (Thyroid) — Higher activity
  • DIO2 (Thyroid) — Higher activity
  • SUOX (PCOS/ Blood Sugar) — Higher activity
  • LPL (Weight) — Higher activity
  • AMY1A (Starch Digestion) — Higher activity
  • Fluoride Sensitivity — Higher
  • NQO1 (Detox) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
Running below the typical range  (14)
  • Belly Fat — Lower levels, 16th percentile
  • Weight Loss from Calorie Restriction — Lower
  • Metabolic Rate — Lower
  • GLP-1 — Lower levels
  • Postprandial Glucose — Lower levels
  • SLC30A8 (Blood Sugar) — Lower activity
  • UCP1 (Weight) — Lower activity
  • CDKN2B (Blood Sugar) — Lower activity
  • PPM1K (Blood Sugar/Diet) — Lower activity
  • MADD (Blood Sugar & Insulin) — Lower activity
  • ADCY5 (Blood Sugar) — Lower activity
  • FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
  • PLIN (Weight, Blood Sugar) — Lower activity
  • SOD2 (Oxidative Stress) — Lower activity
Working in your favour  (4)
  • FTO (Weight) — Better
  • FTO (Overeating) — Better
  • TMEM18 (Weight) — Better genetics
  • IL6R (Weight) — Better genetics
In line with most people  (66)
  • Underweight — Typical likelihood, 79th percentile
  • Weight Regain — Typical likelihood, 72th percentile
  • Gout — Typical likelihood, 58th percentile
  • Type 2 Diabetes — Typical likelihood, 49th percentile
  • Hashimoto's Disease — Typical likelihood, 47th percentile
  • Overactive Thyroid — Typical likelihood, 46th percentile
  • Insulin Resistance — Typical, 43th percentile
  • ADRA2A (Blood Sugar) — Typical activity, 42th percentile
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Underactive Thyroid — Typical likelihood, 34th percentile
  • Lead — Typical levels, 28th percentile
  • Pesticide Sensitivity — Typical, 18th percentile
  • Uric Acid — Typical levels, 16th percentile
  • Arsenic — Typical levels, 16th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Fasting Glucose — Typical levels
  • HbA1c — Typical levels
  • Insulin — Typical levels
  • Graves' Disease — Typical likelihood
  • TSH — Typical levels
  • T3 (Triiodothyronine) — Typical levels
  • T4 (Thyroxine) — Typical levels
  • Free T4 — Typical levels
  • Reverse T3 (rT3) — Typical levels
  • Free T3 (fT3) — Typical levels
  • Ketone Bodies — Typical levels
  • Lactate — Typical levels
  • Creatine — Typical levels
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • UCP2 (Weight) — Typical activity
  • UCP3 (Weight) — Typical activity
  • ADRB3 (Weight) — Typical activity
  • CD36 (Fat Preference/Weight) — Typical activity
  • TFAP2B (Weight/Diet) — Typical activity
  • PPARG (Metabolism) — Typical activity
  • APOA2 (Weight, Blood Lipids) — Typical activity
  • MC3R (Weight) — Typical activity
  • TPO (Thyroid) — Typical
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • GCKR (Blood Sugar) — Typical activity
  • GIPR (Blood Sugar) — Typical activity
  • PPARA (Keto Diet) — Typical activity
  • Diabetic Retinopathy — Typical likelihood
  • CRY2 (Blood Sugar) — Typical genetics
  • Adiponectin — Typical levels
  • Ghrelin — Typical levels
  • Leptin — Typical levels
  • CLOCK (Sleep & Weight) — Typical activity
  • PER2 (Dieting) — Typical genetics
  • SIRT1 (Longevity) — Typical activity
  • Detox — Typical ability
  • Oxidative Stress — Typical
  • Benzene Sensitivity — Typical
  • NFE2L2/NRF2 (Detox) — Typical activity
  • Sensitivity to Airborne Mold — Typical
  • Sensitivity to Foodborne Mold — Typical
  • Multiple Chemical Sensitivity — Typical likelihood
  • BPA Sensitivity — Typical
  • Mercury — Typical levels
  • Phase I Detox — Typical ability
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL6 Gene (Inflammation) — Typical activity
  • Cold Intolerance — Typical likelihood
  • TNF Gene (Inflammation) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-04D34E
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-04D34E · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Metabolic Health

Personalized Genetic Report
Weight ControlBlood Sugar ControlThyroid HealthMiscellaneousMetabolism Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-1CC153
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-1CC153
Panel
Metabolic Health
Results scored
58 of 61
Need attention
4
Report
Summary Report

What this report covers

Weight Control · Blood Sugar Control · Thyroid Health · Miscellaneous · Metabolism Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 58 results here, 4 came back worth discussing with a clinician and 3 came back in your favour. Bring this document to your appointment.

What this package looks at

Metabolic Health — Is your metabolism optimal? Maybe, but probably not. A recent study indicated that only about 1 in 8 people in the U.S. have optimal metabolic health [R].

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: ADRB2 (Weight), Visceral Fat
relevance
2
Limit Calorie Intake

Consume fewer calories than your body needs for maintenance.

Relates to: UCP1 (Weight), FOXO1 (Blood Sugar), Visceral Fat
relevance
3
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: TCF7L2 (Blood Sugar/Diet), Visceral Fat
relevance
4
High-Intensity Interval Training (HIIT)30 minutes

Engage in HIIT workouts for at least 30 minutes per session, 3 times a week.

Relates to: Visceral Fat
relevance
5
Regular Sleep Schedule

Aim for 7-9 hours of sleep per night.

Relates to: Visceral Fat, Low Blood Sugar
relevance
6
Whole Grains

Aim to replace refined grains with whole grains at each meal for optimal benefits.

Relates to: TCF7L2 (Blood Sugar/Diet), Visceral Fat
relevance
7
Low-Carbohydrate Diet

Limit your daily intake of carbohydrates to less than 26% of your total daily calories.

Relates to: Visceral Fat
relevance
8
Yacon

prebiotic and blood sugar-lowering properties.

Relates to: TCF7L2 (Blood Sugar/Diet)
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Zinc
Relates to: SLC30A8 (Blood Sugar)
relevance
2
Balance Iodine Intake
Relates to: Visceral Fat
relevance
3
Probiotics
Relates to: Visceral Fat, GLP-1
relevance
4
Glutamine
Relates to: GLP-1, TCF7L2 (Blood Sugar/Diet)
relevance
5
Resveratrol
Relates to: FOXO1 (Blood Sugar)
relevance
6
Caffeine
Relates to: ADRB2 (Weight)
relevance

Your headline findings

Of the 58 results in this package, these 4 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Low Blood SugarMore likely
More likely to have low blood sugar based on 126,569 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Other non-diabetic risk factors include age, drinking alcohol, certain medications, severe infections, problems with your adrenal or pituitary gland, liver, kidney, or pancreas.

Other diabetic risk factors include taking too much diabetes medication, not eating enough or skipping meals, increasing physical activity without adjusting diet or medications, and drinking alcohol.

If you have high genetic risk, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Regular Sleep Schedule
    Aim for 7-9 hours of sleep per night.
From your Metabolic Health report
Heavy SweatingMore likely
More likely to have hyperhidrosis based on 104 genetic variants we looked at
Your risk is greater than 91% of the population and lower than 9% of the population.

What this actually is

Key Takeaways: Genes that affect excessive sweating may influence nerve function and chemical messengers.

Excessive sweating can impact quality of life and cause undue stress and anxiety.

If you have symptoms, you may want to consult your doctor to rule out other conditions.

From your Metabolic Health report
ADRB2 (Weight)Worse genetics
Higher predisposition than average

What this actually is

The rs1042714 variant (also known as Q27E or Gln27Glu) has been most widely researched when it comes to weight.

Its minor ‘G’ allele (Glu, E) was associated with approximately 20% higher odds of obesity in a meta-analysis of 18 studies.

An older meta-analysis came to a similar conclusion.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Ask your clinician about

  • Caffeine

Named only. Marrow gives no dose and does not recommend these.

From your Metabolic Health report
TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average

What this actually is

The two main TCF7L2 variants are rs7903146 and rs12255372.

They are almost always inherited together, which means they act as a single genetic factor.

Their "T" alleles have one of the strongest known links with type 2 diabetes.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Whole Grains
    Aim to replace refined grains with whole grains at each meal for optimal benefits.
  • Whole Grains
    Aim to replace refined grains with whole grains at each meal for optimal benefits.
From your Metabolic Health report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.

Weight gain affects conditions like high blood sugar and heart disease.

However, it is highly modifiable by diet and exercise.

From your Metabolic Health report
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Metabolic Health report
FTO (Weight)Better
Lower predisposition than average

What this actually is

An SNP in this gene, rs9939609, has shown a robust association with obesity across different ages and ethnic groups.

Carriers of the minor 'A' allele tend to gain more weight and have higher rates of obesity [R, R, R, R].

Many human studies suggest that the 'A' allele at rs9939609 is associated with: Higher levels of ghrelin or the "hunger hormone" Higher food intake [R, R, R] Increased preference for higher-calorie foods [R, R, R] Increased enjoyment of food Not feeling full after meals [R, R, R] Eating in the absence of hunger [R, R] Food cravings Emotional and binge eating In contrast, the 'T' allele is linked to normal body weight, more satiety after meals, and possibly healthier dietary choices [R, R, R].

From your Metabolic Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (6)
  • Visceral Fat — Higher levels, 82th percentile
  • FOXO1 (Blood Sugar) — Higher activity
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
  • DIO1 (Thyroid) — Higher activity
  • DIO2 (Thyroid) — Higher activity
Running below the typical range  (9)
  • Weight Loss from Calorie Restriction — Lower
  • Metabolic Rate — Lower
  • GLP-1 — Lower levels
  • Postprandial Glucose — Lower levels
  • SLC30A8 (Blood Sugar) — Lower activity
  • UCP1 (Weight) — Lower activity
  • CDKN2B (Blood Sugar) — Lower activity
  • PPM1K (Blood Sugar/Diet) — Lower activity
  • MADD (Blood Sugar & Insulin) — Lower activity
In line with most people  (36)
  • Weight Regain — Typical likelihood, 72th percentile
  • Gout — Typical likelihood, 58th percentile
  • Type 2 Diabetes — Typical likelihood, 49th percentile
  • Hashimoto's Disease — Typical likelihood, 47th percentile
  • Overactive Thyroid — Typical likelihood, 46th percentile
  • Insulin Resistance — Typical, 43th percentile
  • Underactive Thyroid — Typical likelihood, 34th percentile
  • Uric Acid — Typical levels, 16th percentile
  • Fasting Glucose — Typical levels
  • HbA1c — Typical levels
  • Insulin — Typical levels
  • Graves' Disease — Typical likelihood
  • TSH — Typical levels
  • T3 (Triiodothyronine) — Typical levels
  • T4 (Thyroxine) — Typical levels
  • Free T4 — Typical levels
  • Reverse T3 (rT3) — Typical levels
  • Free T3 (fT3) — Typical levels
  • Ketone Bodies — Typical levels
  • Lactate — Typical levels
  • Creatine — Typical levels
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • UCP2 (Weight) — Typical activity
  • UCP3 (Weight) — Typical activity
  • ADRB3 (Weight) — Typical activity
  • CD36 (Fat Preference/Weight) — Typical activity
  • TFAP2B (Weight/Diet) — Typical activity
  • PPARG (Metabolism) — Typical activity
  • APOA2 (Weight, Blood Lipids) — Typical activity
  • MC3R (Weight) — Typical activity
  • TPO (Thyroid) — Typical
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • GCKR (Blood Sugar) — Typical activity
  • GIPR (Blood Sugar) — Typical activity
  • PPARA (Keto Diet) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-1CC153
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-1CC153 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Blood Sugar Control

Personalized Genetic Report
Diabetes & ComplicationsBlood Sugar ControlBlood Sugar MarkersBlood Sugar Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-30091D
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-30091D
Panel
Blood Sugar Control
Results scored
35 of 38
Need attention
5
Report
Summary Report

What this report covers

Diabetes & Complications · Blood Sugar Control · Blood Sugar Markers · Blood Sugar Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 35 results here, 5 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.

What this package looks at

Blood Sugar Control — Blood sugar control is essential for maintaining energy levels, supporting metabolic health, and preventing long-term complications. Genetic predispositions can significantly influence how well your body regulates blood sugar. These genetic factors may affect insulin sensitivity, glucose

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Sugary Foods & Drinks

Aim to do this daily for ongoing health benefits.

Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
2
Limit Calorie Intake

Consume fewer calories than your body needs for maintenance.

Relates to: FOXO1 (Blood Sugar)
relevance
3
Intermittent Fasting

Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.

Relates to: GLP-1, FOXO1 (Blood Sugar), MTNR1B (Diet & Blood Sugar), TCF7L2 (Blood Sugar/Diet)
relevance
4
Okra
Relates to: Diabetic Nephropathy
relevance
5
Infrared Light Therapy

After one month, the patients’ ulcers shrank in size and had fewer secretions.

Relates to: Diabetic Foot Ulcers, FOXO1 (Blood Sugar)
relevance
6
Kimchi

Incorporate about a half cup of kimchi into one of your daily meals.

Relates to: TCF7L2 (Blood Sugar/Diet)
relevance
7
Yacon

prebiotic and blood sugar-lowering properties.

Relates to: TCF7L2 (Blood Sugar/Diet)
relevance
8
Avoid Organochlorine Pesticide Exposure

Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.

Relates to: Diabetic Nephropathy
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Berberine
Relates to: FOXO1 (Blood Sugar), TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
2
Zinc
Relates to: SLC30A8 (Blood Sugar), Diabetic Foot Ulcers
relevance
3
Resveratrol
Relates to: FOXO1 (Blood Sugar), Diabetic Nephropathy
relevance
4
Alpha-Lipoic Acid
Relates to: Diabetic Neuropathy
relevance
5
Glutamine
Relates to: GLP-1, TCF7L2 (Blood Sugar/Diet)
relevance
6
Tocotrienols
Relates to: Diabetic Neuropathy
relevance

Your headline findings

Of the 35 results in this package, these 5 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Low Blood SugarMore likely
More likely to have low blood sugar based on 126,569 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.

What this actually is

Other non-diabetic risk factors include age, drinking alcohol, certain medications, severe infections, problems with your adrenal or pituitary gland, liver, kidney, or pancreas.

Other diabetic risk factors include taking too much diabetes medication, not eating enough or skipping meals, increasing physical activity without adjusting diet or medications, and drinking alcohol.

If you have high genetic risk, you may lower overall risk by taking action on those factors that you can change.

What you can do

  • Honey
    Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.
From your Blood Sugar Control report
Diabetic NeuropathyMore likely
More likely to have diabetic neuropathy based on 1,658 genetic variants we looked at

What this actually is

Prolonged exposure to high blood sugar levels is the primary cause of diabetic neuropathy.

However, other factors that might increase the risk or severity of diabetic neuropathy include: Smoking Alcohol abuse Obesity High blood pressure Kidney disease Genetics Specific genetic variations might render some individuals more vulnerable to the neurotoxic effects of high blood sugar.

Hence, while some people with diabetes may never develop neuropathy, others might face complications even with good glucose control.

Ask your clinician about

  • Alpha-Lipoic Acid
  • Tocotrienols
  • Coenzyme Q10 (CoQ10)

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
Diabetic Foot UlcersMore likely
Higher predisposition than average

What this actually is

The following factors may increase the risk of diabetic foot ulcers: Peripheral neuropathy, which reduces the ability to feel pain and detect injuries.

Poor blood circulation, which compromises skin health and healing ability.

Foot deformities, which increase the risk of pressure sores.

What you can do

  • Infrared Light Therapy
    After one month, the patients’ ulcers shrank in size and had fewer secretions.
  • Honey
    Its osmotic effect also draws out excess fluid from the ulcer, speeding up the healing process.

Ask your clinician about

  • Zinc

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
Diabetic NephropathyMore likely
More likely to have diabetic nephropathy based on 28,985 genetic variants we looked at

What this actually is

Factors linked to an increased risk of diabetic nephropathy include: Poorly controlled blood sugar levels High blood pressure Long duration of diabetes Smoking Obesity Family history of kidney disease High cholesterol levels Managing diabetic nephropathy involves controlling blood sugar and blood pressure, alongside lifestyle changes.

Common treatments include: Medications: ACE inhibitors or ARBs to control blood pressure, blood sugar-lowering drugs, and statins for cholesterol management.

Dietary changes: Low-protein and low-sodium diets to reduce kidney strain.

What you can do

  • Okra
  • Avoid Organochlorine Pesticide Exposure
    Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.

Ask your clinician about

  • Resveratrol

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report
TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average

What this actually is

The two main TCF7L2 variants are rs7903146 and rs12255372.

They are almost always inherited together, which means they act as a single genetic factor.

Their "T" alleles have one of the strongest known links with type 2 diabetes.

What you can do

  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.
  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.

Ask your clinician about

  • Berberine

Named only. Marrow gives no dose and does not recommend these.

From your Blood Sugar Control report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Blood Sugar Control report
Sugar CravingsLess likely
Less likely to crave sugar based on 673,476 genetic variants we looked at
Your risk is greater than 20% of the population and lower than 80% of the population.

What this actually is

People who have less sensitive sweet receptors may have a “sweet tooth.” They may prefer sweet foods and eat more of them [R, R, R].

From your Blood Sugar Control report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (5)
  • IRS1 (Metabolic Health) — Higher activity, 85th percentile
  • FOXO1 (Blood Sugar) — Higher activity
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
  • SUOX (PCOS/ Blood Sugar) — Higher activity
Running below the typical range  (9)
  • GLP-1 — Lower levels
  • Postprandial Glucose — Lower levels
  • CDKN2B (Blood Sugar) — Lower activity
  • PPM1K (Blood Sugar/Diet) — Lower activity
  • SLC30A8 (Blood Sugar) — Lower activity
  • MADD (Blood Sugar & Insulin) — Lower activity
  • ADCY5 (Blood Sugar) — Lower activity
  • FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
  • PLIN (Weight, Blood Sugar) — Lower activity
In line with most people  (14)
  • Type 2 Diabetes — Typical likelihood, 49th percentile
  • Insulin Resistance — Typical, 43th percentile
  • ADRA2A (Blood Sugar) — Typical activity, 42th percentile
  • Type 1 Diabetes — Typical likelihood, 15th percentile
  • Diabetic Retinopathy — Typical likelihood
  • Fasting Glucose — Typical levels
  • HbA1c — Typical levels
  • Insulin — Typical levels
  • Ketone Bodies — Typical levels
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • GCKR (Blood Sugar) — Typical activity
  • GIPR (Blood Sugar) — Typical activity
  • CRY2 (Blood Sugar) — Typical genetics
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-30091D
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-30091D · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Weight & Body Fat

Personalized Genetic Report
Weight ManagementMetabolism & Body CompositionWeight MarkersWeight Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-093562
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-093562
Panel
Weight & Body Fat
Results scored
33
Need attention
1
Report
Summary Report

What this report covers

Weight Management · Metabolism & Body Composition · Weight Markers · Weight Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 33 results here, 1 came back worth discussing with a clinician and 6 came back in your favour. Bring this document to your appointment.

What this package looks at

Weight & Body Fat — Weight management and body fat distribution are influenced by a combination of environmental factors, lifestyle choices, and genetics. Genetic predispositions can significantly affect your tendency to gain or lose weight, how your body stores fat, and how efficiently your

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: ADRB2 (Weight), Visceral Fat
relevance
2
Limit Calorie Intake

Consume fewer calories than your body needs for maintenance.

Relates to: UCP1 (Weight), Visceral Fat
relevance
3
Intermittent Fasting

Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.

Relates to: ADRB2 (Weight), Visceral Fat
relevance
4
High-Intensity Interval Training (HIIT)30 minutes

Engage in HIIT workouts for at least 30 minutes per session, 3 times a week.

Relates to: Visceral Fat
relevance
5
Keto Diet

Adopt a diet that consists of about 70-80% fat, 10-20% protein, and 5-10% carbohydrates.

Relates to: Visceral Fat
relevance
6
Low-Carbohydrate Diet

Limit your daily intake of carbohydrates to less than 26% of your total daily calories.

Relates to: Visceral Fat
relevance
7
Soccer30 minutes

Engage in a game of soccer for at least 30 minutes, three times a week.

Relates to: Visceral Fat
relevance
8
Eat More Protein and Less Carbs

Include a source of lean protein such as chicken, fish, beans, or tofu in each meal, aiming for per serving, while reducing carbohydrate-rich foods like bread, pasta, and sweets, aiming to make proteins about 30-40% of your daily caloric intake.

Relates to: Visceral Fat
relevance
9
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Visceral Fat
relevance
10
Aquatic Exercise

Participate in aquatic exercise sessions, such as swimming or water aerobics, for 60 minutes, 3 to 5 times per TA week.

Relates to: Visceral Fat
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Probiotics
Relates to: Visceral Fat
relevance
2
Caffeine
Relates to: ADRB2 (Weight)
relevance
3
Dietary Vitamin A
Relates to: Visceral Fat
relevance

Your headline findings

Of the 33 results in this package, these 1 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

ADRB2 (Weight)Worse genetics
Higher predisposition than average

What this actually is

The rs1042714 variant (also known as Q27E or Gln27Glu) has been most widely researched when it comes to weight.

Its minor ‘G’ allele (Glu, E) was associated with approximately 20% higher odds of obesity in a meta-analysis of 18 studies.

An older meta-analysis came to a similar conclusion.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Intermittent Fasting
    Limit your daily eating to a specific window of time, typically within an 8-hour period such as from 12 pm to 8 pm, and fast for the remaining 16 hours of the day.

Ask your clinician about

  • Caffeine

Named only. Marrow gives no dose and does not recommend these.

From your Weight & Body Fat report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

OverweightLess likely
Less likely to be overweight or obese based on 455,505 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Up to 42% of adults and 19% of children in the US meet the medical criteria for obesity.

Weight gain affects conditions like high blood sugar and heart disease.

However, it is highly modifiable by diet and exercise.

From your Weight & Body Fat report
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.

A history of diabetes in one's family.

A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.

From your Weight & Body Fat report
FTO (Overeating)Better
Lower predisposition than average

What this actually is

Genetics may play a related gene is gene.

From your Weight & Body Fat report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (4)
  • Visceral Fat — Higher levels, 82th percentile
  • LPL (Weight) — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
  • AMY1A (Starch Digestion) — Higher activity
Running below the typical range  (5)
  • Belly Fat — Lower levels, 16th percentile
  • Weight Loss from Calorie Restriction — Lower
  • Metabolic Rate — Lower
  • UCP1 (Weight) — Lower activity
  • PLIN (Weight, Blood Sugar) — Lower activity
Working in your favour  (3)
  • FTO (Weight) — Better
  • TMEM18 (Weight) — Better genetics
  • IL6R (Weight) — Better genetics
In line with most people  (17)
  • Underweight — Typical likelihood, 79th percentile
  • Weight Regain — Typical likelihood, 72th percentile
  • Adiponectin — Typical levels
  • Ghrelin — Typical levels
  • Leptin — Typical levels
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • UCP2 (Weight) — Typical activity
  • UCP3 (Weight) — Typical activity
  • ADRB3 (Weight) — Typical activity
  • CD36 (Fat Preference/Weight) — Typical activity
  • CLOCK (Sleep & Weight) — Typical activity
  • TFAP2B (Weight/Diet) — Typical activity
  • PPARG (Metabolism) — Typical activity
  • APOA2 (Weight, Blood Lipids) — Typical activity
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • MC3R (Weight) — Typical activity
  • PER2 (Dieting) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-093562
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-093562 · © 2026 Marrow Health.

Marrow
Genomics · Genetic Reports · Precision Wellness

Mitochondrial Support

Personalized Genetic Report
Mitochondrial HealthDetox & Oxidative StressInflammationCold Exposure
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-C70CF2
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-C70CF2
Panel
Mitochondrial Support
Results scored
28
Need attention
2
Report
Summary Report

What this report covers

Mitochondrial Health · Detox & Oxidative Stress · Inflammation · Cold Exposure

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 28 results here, 2 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Mitochondrial Support — Think of mitochondria as tiny power plants inside each of your cells, converting the food you eat into energy that keeps you alive and thriving. But these remarkable cellular structures do much more than just produce energy -they're key players in your overall health and vitality.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Exposure to Molds

Keep indoor humidity levels below 50% by using dehumidifiers or air conditioners, ensure proper ventilation in areas like bathrooms and kitchens, fix leaks promptly, and clean up any water damage within 24-48 hours to prevent mold growth.

Relates to: Excessive Mast Cells
relevance
2
Avoid Exposure to Solvents

Wear protective gloves and masks when using solvent-based products such as paint thinners, degreasers, or nail polish removers.

Relates to: Excessive Mast Cells
relevance
3
Sunlight Exposure20 minutes

Expose your skin to direct sunlight for about 10-30 minutes several times per week, preferably during midday TA when the sun is strongest.

Relates to: Excessive Mast Cells
relevance
4
Avoid Exposure to Heavy Metals

Check for lead-based paints in older homes and avoid cooking or storing food in uncoated metal containers.

Relates to: Excessive Mast Cells
relevance
5
Low-Histamine Diet

Exclude high-histamine foods such as aged cheeses, smoked meats, fermented products like sauerkraut and kombucha, alcohol, and preserved foods. for at least 4 weeks to observe any improvements in symptoms.

Relates to: Excessive Mast Cells
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Quercetin
Relates to: Excessive Mast Cells
relevance
2
Rutin
Relates to: SOD2 (Oxidative Stress), Excessive Mast Cells
relevance
3
Manganese supplements
Relates to: SOD2 (Oxidative Stress)
relevance
4
Vitamin C
Relates to: Excessive Mast Cells
relevance
5
Dietary Omega-3 Fatty Acids
Relates to: Excessive Mast Cells
relevance
6
Turmeric
Relates to: Excessive Mast Cells
relevance
7
Maintain Optimal Vitamin D Levels
Relates to: Excessive Mast Cells
relevance

Your headline findings

Of the 28 results in this package, these 2 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Excessive Mast CellsMore likely
More likely to have excessive mast cells based on 14 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Mastocytosis is often linked to mutations in the KIT gene, which plays a role in mast cell growth and development.

These mutations are usually acquired during a person's life rather than being inherited.

Other, less important risk factors include: Family history: Rare cases may run in families, but most are sporadic.

Ask your clinician about

  • Quercetin
  • Rutin
  • Vitamin C

Named only. Marrow gives no dose and does not recommend these.

From your Mitochondrial Support report
Mitochondrial Health (Functional)Worse
Higher predisposition than average
From your Mitochondrial Support report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (4)
  • Fluoride Sensitivity — Higher
  • NQO1 (Detox) — Higher activity
  • GPX1 (Glutathione/Detox) — Higher activity
  • SUOX (PCOS/ Blood Sugar) — Higher activity
Running below the typical range  (1)
  • SOD2 (Oxidative Stress) — Lower activity
In line with most people  (21)
  • Inflammation (CRP) — Typical levels, 36th percentile
  • Lead — Typical levels, 28th percentile
  • Pesticide Sensitivity — Typical, 18th percentile
  • Arsenic — Typical levels, 16th percentile
  • SIRT1 (Longevity) — Typical activity
  • Detox — Typical ability
  • Oxidative Stress — Typical
  • Benzene Sensitivity — Typical
  • NFE2L2/NRF2 (Detox) — Typical activity
  • Sensitivity to Airborne Mold — Typical
  • Sensitivity to Foodborne Mold — Typical
  • Multiple Chemical Sensitivity — Typical likelihood
  • BPA Sensitivity — Typical
  • Mercury — Typical levels
  • Phase I Detox — Typical ability
  • IgE — Typical levels
  • IL-10 — Typical levels
  • IL6 Gene (Inflammation) — Typical activity
  • Cold Intolerance — Typical likelihood
  • PPARGC1A (Fitness/Blood Sugar) — Typical activity
  • TNF Gene (Inflammation) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-C70CF2
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-C70CF2 · © 2026 Marrow Health.